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Jacob Lewis
Jacob Lewis
University of Wollongong
Verified email at crick.ac.uk
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Cited by
Cited by
Year
Single-molecule visualization of fast polymerase turnover in the bacterial replisome
JS Lewis, LM Spenkelink, S Jergic, EA Wood, E Monachino, NP Horan, ...
Elife 6, e23932, 2017
1212017
The E. coli DNA replication fork
JS Lewis, S Jergic, NE Dixon
The Enzymes 39, 31-88, 2016
84*2016
Tunability of DNA polymerase stability during eukaryotic DNA replication
JS Lewis, LM Spenkelink, GD Schauer, O Yurieva, SH Mueller, ...
Molecular cell 77 (1), 17-25. e5, 2020
792020
Single-molecule visualization of Saccharomyces cerevisiae leading-strand synthesis reveals dynamic interaction between MTC and the replisome
JS Lewis, LM Spenkelink, GD Schauer, FR Hill, RE Georgescu, ...
Proceedings of the National Academy of Sciences 114 (40), 10630-10635, 2017
652017
Nuclease dead Cas9 is a programmable roadblock for DNA replication
KS Whinn, G Kaur, JS Lewis, GD Schauer, SH Mueller, S Jergic, ...
Scientific reports 9 (1), 13292, 2019
582019
Recycling of single-stranded DNA-binding protein by the bacterial replisome.
LM Spenkelink, JS Lewis, S Jergic, ZQ Xu, A Robinson, NE Dixon, ...
Nucleic Acid Research, gkz090, 2019
522019
Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response
H Ghodke, BP Paudel, JS Lewis, S Jergic, K Gopal, ZJ Romero, EA Wood, ...
Elife 8, e42761, 2019
502019
Mechanism of replication origin melting nucleated by CMG helicase assembly
JS Lewis, MH Gross, J Sousa, SS Henrikus, JF Greiwe, A Nans, ...
Nature 606 (7916), 1007-1014, 2022
412022
Replisome bypass of a protein-based R-loop block by Pif1
GD Schauer, LM Spenkelink, JS Lewis, O Yurieva, SH Mueller, ...
Proceedings of the National Academy of Sciences 117 (48), 30354-30361, 2020
372020
Shining a spotlight on DNA: single-molecule methods to visualise DNA
G Kaur, JS Lewis, AM van Oijen
Molecules 24 (3), 491, 2019
352019
A primase-induced conformational switch controls the stability of the bacterial replisome
E Monachino, S Jergic, JS Lewis, ZQ Xu, ATY Lo, VL O’Shea, JM Berger, ...
Molecular cell 79 (1), 140-154. e7, 2020
202020
Design of customizable long linear DNA substrates with controlled end modifications for single-molecule studies
SH Mueller, LM Spenkelink, AM van Oijen, JS Lewis
Analytical biochemistry 592, 113541, 2020
192020
Caught in the act: structural dynamics of replication origin activation and fork progression
JS Lewis, A Costa
Biochemical Society Transactions 48 (3), 1057, 2020
162020
The E. coli helicase does not use ATP during replication
LM Spenkelink, RR Spinks, S Jergic, JS Lewis, NE Dixon, AM van Oijen
bioRxiv, 2021.07. 07.451541, 2021
72021
Production of long linear DNA substrates with site-specific chemical lesions for single-molecule replisome studies
G Kaur, LM Spenkelink, JS Lewis, S Jergic, NE Dixon, AM van Oijen
Methods in enzymology 672, 299-315, 2022
42022
Embracing Heterogeneity: Challenging the Paradigm of Replisomes as Deterministic Machines
JS Lewis, AM van Oijen, LM Spenkelink
Chemical Reviews 123 (23), 13419-13440, 2023
2023
Direct observation of Shelterin dynamics and T-loop formation at telomeres
MD Newton, JS Lewis, R Anand, EP Holmes, ALB Pyne, SJ Boulton
Biophysical Journal 122 (3), 9a-10a, 2023
2023
Resolving the Gordian Knot: Srs2 Strips Intermediates Formed during Homologous Recombination
H Ghodke, JS Lewis, AM van Oijen
Trends in biochemical sciences 43 (3), 149-151, 2018
2018
Structural dynamics and protein interactions within the E. coli DNA polymerase III holoenzyme
JS Lewis
2017
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Articles 1–19