Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation LA Gates, J Shi, AD Rohira, Q Feng, B Zhu, MT Bedford, CA Sagum, ... Journal of Biological Chemistry 292 (35), 14456-14472, 2017 | 225 | 2017 |
Histone marks in the ‘driver’s seat’: functional roles in steering the transcription cycle LA Gates, CE Foulds, BW O’malley Trends in biochemical sciences 42 (12), 977-989, 2017 | 185 | 2017 |
Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics CE Foulds, Q Feng, C Ding, S Bailey, TL Hunsaker, A Malovannaya, ... Molecular cell 51 (2), 185-199, 2013 | 125 | 2013 |
Impaired cell fate through gain-of-function mutations in a chromatin reader L Wan, S Chong, F Xuan, A Liang, X Cui, L Gates, TS Carroll, Y Li, L Feng, ... Nature 577 (7788), 121-126, 2020 | 98 | 2020 |
Coactivator-dependent oscillation of chromatin accessibility dictates circadian gene amplitude via REV-ERB loading B Zhu, LA Gates, E Stashi, S Dasgupta, N Gonzales, A Dean, CC Dacso, ... Molecular cell 60 (5), 769-783, 2015 | 72 | 2015 |
Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets LA Gates, G Gu, Y Chen, AD Rohira, JT Lei, RA Hamilton, Y Yu, ... Oncogene 37 (33), 4581-4598, 2018 | 60 | 2018 |
ZBTB1 regulates asparagine synthesis and leukemia cell response to L-asparaginase RT Williams, R Guarecuco, LA Gates, D Barrows, MC Passarelli, B Carey, ... Cell metabolism 31 (4), 852-861. e6, 2020 | 52 | 2020 |
In situ chromatin interactomics using a chemical bait and trap approach AJ Burton, M Haugbro, LA Gates, JD Bagert, CD Allis, TW Muir Nature chemistry 12 (6), 520-527, 2020 | 51 | 2020 |
Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency Z Zhang, BC Nikolai, LA Gates, SY Jung, EB Siwak, B He, AP Rice, ... Nucleic Acids Research 45 (16), 9348-9360, 2017 | 51 | 2017 |
Trapping of cis-2-butene-1, 4-dial to measure furan metabolism in human liver microsomes by cytochrome P450 enzymes LA Gates, D Lu, LA Peterson Drug Metabolism and Disposition 40 (3), 596-601, 2012 | 48 | 2012 |
Comparative metabolism of furan in rodent and human cryopreserved hepatocytes LA Gates, MB Phillips, BA Matter, LA Peterson Drug Metabolism and Disposition 42 (7), 1132-1136, 2014 | 27 | 2014 |
Abundant rodent furan-derived urinary metabolites are associated with tobacco smoke exposure in humans AE Grill, T Schmitt, LA Gates, D Lu, D Bandyopadhyay, JM Yuan, ... Chemical research in toxicology 28 (7), 1508-1516, 2015 | 26 | 2015 |
A molecular switch between mammalian MLL complexes dictates response to Menin–MLL inhibition YM Soto-Feliciano, FJ Sánchez-Rivera, F Perner, DW Barrows, ... Cancer discovery 13 (1), 146-169, 2023 | 14 | 2023 |
Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation PJ Lund, LA Gates, M Leboeuf, SA Smith, L Chau, M Lopes, ES Friedman, ... Cell reports 41 (11), 2022 | 13 | 2022 |
Microbiota-dependent histone butyrylation in the mammalian intestine LA Gates, BS Reis, PJ Lund, MR Paul, M Leboeuf, Z Nadeem, TS Carroll, ... BioRxiv, 2022.09. 29.510184, 2022 | 3 | 2022 |
Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression LA Gates, BS Reis, PJ Lund, MR Paul, M Leboeuf, AM Djomo, Z Nadeem, ... Nature Metabolism, 1-11, 2024 | | 2024 |
P165 INFLUENCE OF THE GUT MICROBIOTA ON COLONIC HISTONE MODIFICATIONS THROUGH BUTYRATE METABOLISM UNDER HEALTHY AND INFLAMMATORY CONDITIONS P Lund, S Smith, J Simithy, L Chau, E Friedman, Y Saiman, L Gates, ... Gastroenterology 158 (3), S67, 2020 | | 2020 |
Human urinary metabolites as possible biomarkers of exposure to furan AE Grill, LA Gates, D Lu, SE Murphy, SS Hecht, LA Peterson ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
LC-MS/MS assay for biomarkers of furan exposure and metabolism in human urine AE Grill, L Gates, L Peterson ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013 | | 2013 |
Comparative metabolism of furan in rodent and human cryopreserved hepatocytes LA Peterson, LA Gates, MB Phillips, BA Matter ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012 | | 2012 |