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Leah Gates
Leah Gates
Assistant Professor, Case Western Reserve University
Verified email at case.edu - Homepage
Title
Cited by
Cited by
Year
Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation
LA Gates, J Shi, AD Rohira, Q Feng, B Zhu, MT Bedford, CA Sagum, ...
Journal of Biological Chemistry 292 (35), 14456-14472, 2017
2252017
Histone marks in the ‘driver’s seat’: functional roles in steering the transcription cycle
LA Gates, CE Foulds, BW O’malley
Trends in biochemical sciences 42 (12), 977-989, 2017
1852017
Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics
CE Foulds, Q Feng, C Ding, S Bailey, TL Hunsaker, A Malovannaya, ...
Molecular cell 51 (2), 185-199, 2013
1252013
Impaired cell fate through gain-of-function mutations in a chromatin reader
L Wan, S Chong, F Xuan, A Liang, X Cui, L Gates, TS Carroll, Y Li, L Feng, ...
Nature 577 (7788), 121-126, 2020
982020
Coactivator-dependent oscillation of chromatin accessibility dictates circadian gene amplitude via REV-ERB loading
B Zhu, LA Gates, E Stashi, S Dasgupta, N Gonzales, A Dean, CC Dacso, ...
Molecular cell 60 (5), 769-783, 2015
722015
Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets
LA Gates, G Gu, Y Chen, AD Rohira, JT Lei, RA Hamilton, Y Yu, ...
Oncogene 37 (33), 4581-4598, 2018
602018
ZBTB1 regulates asparagine synthesis and leukemia cell response to L-asparaginase
RT Williams, R Guarecuco, LA Gates, D Barrows, MC Passarelli, B Carey, ...
Cell metabolism 31 (4), 852-861. e6, 2020
522020
In situ chromatin interactomics using a chemical bait and trap approach
AJ Burton, M Haugbro, LA Gates, JD Bagert, CD Allis, TW Muir
Nature chemistry 12 (6), 520-527, 2020
512020
Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency
Z Zhang, BC Nikolai, LA Gates, SY Jung, EB Siwak, B He, AP Rice, ...
Nucleic Acids Research 45 (16), 9348-9360, 2017
512017
Trapping of cis-2-butene-1, 4-dial to measure furan metabolism in human liver microsomes by cytochrome P450 enzymes
LA Gates, D Lu, LA Peterson
Drug Metabolism and Disposition 40 (3), 596-601, 2012
482012
Comparative metabolism of furan in rodent and human cryopreserved hepatocytes
LA Gates, MB Phillips, BA Matter, LA Peterson
Drug Metabolism and Disposition 42 (7), 1132-1136, 2014
272014
Abundant rodent furan-derived urinary metabolites are associated with tobacco smoke exposure in humans
AE Grill, T Schmitt, LA Gates, D Lu, D Bandyopadhyay, JM Yuan, ...
Chemical research in toxicology 28 (7), 1508-1516, 2015
262015
A molecular switch between mammalian MLL complexes dictates response to Menin–MLL inhibition
YM Soto-Feliciano, FJ Sánchez-Rivera, F Perner, DW Barrows, ...
Cancer discovery 13 (1), 146-169, 2023
142023
Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation
PJ Lund, LA Gates, M Leboeuf, SA Smith, L Chau, M Lopes, ES Friedman, ...
Cell reports 41 (11), 2022
132022
Microbiota-dependent histone butyrylation in the mammalian intestine
LA Gates, BS Reis, PJ Lund, MR Paul, M Leboeuf, Z Nadeem, TS Carroll, ...
BioRxiv, 2022.09. 29.510184, 2022
32022
Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression
LA Gates, BS Reis, PJ Lund, MR Paul, M Leboeuf, AM Djomo, Z Nadeem, ...
Nature Metabolism, 1-11, 2024
2024
P165 INFLUENCE OF THE GUT MICROBIOTA ON COLONIC HISTONE MODIFICATIONS THROUGH BUTYRATE METABOLISM UNDER HEALTHY AND INFLAMMATORY CONDITIONS
P Lund, S Smith, J Simithy, L Chau, E Friedman, Y Saiman, L Gates, ...
Gastroenterology 158 (3), S67, 2020
2020
Human urinary metabolites as possible biomarkers of exposure to furan
AE Grill, LA Gates, D Lu, SE Murphy, SS Hecht, LA Peterson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014
2014
LC-MS/MS assay for biomarkers of furan exposure and metabolism in human urine
AE Grill, L Gates, L Peterson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013
2013
Comparative metabolism of furan in rodent and human cryopreserved hepatocytes
LA Peterson, LA Gates, MB Phillips, BA Matter
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012
2012
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