| Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors MN Serasinghe, SY Wieder, TT Renault, R Elkholi, JJ Asciolla, JL Yao, ... Molecular cell 57 (3), 521-536, 2015 | 349 | 2015 |
| Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis TT Renault, KV Floros, R Elkholi, KA Corrigan, Y Kushnareva, SY Wieder, ... Molecular cell 57 (1), 69-82, 2015 | 208 | 2015 |
| The role of BH3-only proteins in tumor cell development, signaling, and treatment R Elkholi, KV Floros, JE Chipuk Genes & cancer 2 (5), 523-537, 2011 | 130 | 2011 |
| Putting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy? R Elkholi, TT Renault, MN Serasinghe, JE Chipuk Cancer & metabolism 2, 1-15, 2014 | 84 | 2014 |
| MDM2 integrates cellular respiration and apoptotic signaling through NDUFS1 and the mitochondrial network R Elkholi, I Abraham-Enachescu, AP Trotta, C Rubio-Patiño, ... Molecular cell 74 (3), 452-465. e7, 2019 | 50 | 2019 |
| How do I kill thee? Let me count the ways: p53 regulates PARP‐1 dependent necrosis R Elkholi, JE Chipuk Bioessays 36 (1), 46-51, 2014 | 39 | 2014 |
| Sensitization to the mitochondrial pathway of apoptosis augments melanoma tumor cell responses to conventional chemotherapeutic regimens RA Anvekar, JJ Asciolla, E Lopez-Rivera, KV Floros, S Izadmehr, ... Cell death & disease 3 (11), e420-e420, 2012 | 34 | 2012 |
| B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro-and anti-apoptotic BCL-2 family … TT Renault, R Elkholi, A Bharti, JE Chipuk Journal of Biological Chemistry 289 (38), 26481-26491, 2014 | 31 | 2014 |
| Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination RA Chong, K Wu, DE Spratt, Y Yang, C Lee, J Nayak, M Xu, R Elkholi, ... Proceedings of the National Academy of Sciences 111 (23), 8434-8439, 2014 | 28 | 2014 |
| Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models X Zhang, H Lv, Q Zhou, R Elkholi, JE Chipuk, MVR Reddy, EP Reddy, ... Molecular cancer therapeutics 13 (5), 1105-1116, 2014 | 24 | 2014 |
| BH3 mimetics demonstrate differential activities dependent upon the functional repertoire of pro-and anti-apoptotic BCL-2 family proteins TT Renault, R Elkholi, A Bharti, JE Chipuk J Biol Chem 289, 26481-26491, 2014 | 6 | 2014 |
| Outer mitochondrial membrane shape engages BAX α9 to initiate mitochondrial outer membrane permeabilization and apoptosis TT Renault, KV Floros, R Elkholi, KA Corrigan, Y Kushnareva, SY Wieder, ... Molecular cell 57 (1), 69, 2015 | 1 | 2015 |
| 292 p53 Transcriptionally activates IRF9 to enhance antiviral immunity C Muñoz-Fontela, S Macip, L Martínez-Sobrido, R Elkholi, L Brown, ... Cytokine 3 (43), 312-313, 2008 | 1 | 2008 |
| From zero to sixty: cell death signaling in the city that never sleeps JD Gelles, R Elkholi, MN Serasinghe, MPA Luna-Vargas, JE Chipuk Oncogene 35 (11), 1457-1460, 2016 | | 2016 |
| Novel Functions of MDM2 in Cellular Stress and Commitment to Cell Death R Elkholi Icahn School of Medicine at Mount Sinai, 2016 | | 2016 |
| BH3 Mimetics Demonstrate Differential A Bharti, JE Chipuk, TT Renault, R Elkholi | | 2014 |
| Supplemental Information Mitochondrial Division Is Requisite to RAS-Induced Transformation and Targeted by Oncogenic MAPK Pathway Inhibitors MN Serasinghe, SY Wieder, TT Renault, R Elkholi, JJ Asciolla, JL Yao, ... | | |
