| Inhibition of diverse DsbA enzymes in multi-DsbA encoding pathogens M Totsika, D Vagenas, JJ Paxman, G Wang, R Dhouib, P Sharma, ... Antioxidants & redox signaling 29 (7), 653-666, 2018 | 40 | 2018 |
| Ligand-Induced Conformational Change of Plasmodium falciparum AMA1 Detected Using 19F NMR X Ge, CA MacRaild, SM Devine, CO Debono, G Wang, PJ Scammells, ... Journal of Medicinal Chemistry 57 (15), 6419-6427, 2014 | 36 | 2014 |
| Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules JJ Paxman, AW Lo, MJ Sullivan, S Panjikar, M Kuiper, AE Whitten, ... Nature communications 10 (1), 1967, 2019 | 28 | 2019 |
| The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors LF Duncan, G Wang, OV Ilyichova, MJ Scanlon, B Heras, BM Abbott Molecules 24 (20), 3756, 2019 | 27 | 2019 |
| The Scs disulfide reductase system cooperates with the metallochaperone CueP in Salmonella copper resistance P Subedi, JJ Paxman, G Wang, AA Ukuwela, Z Xiao, B Heras Journal of Biological Chemistry 294 (44), 15876-15888, 2019 | 26 | 2019 |
| Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX) MR Bentley, OV Ilyichova, G Wang, ML Williams, G Sharma, WS Alwan, ... Journal of Medicinal Chemistry 63 (13), 6863-6875, 2020 | 24 | 2020 |
| Improved synthesis of biotinol-5′-AMP: Implications for antibacterial discovery W Tieu, SW Polyak, AS Paparella, MY Yap, TP Soares da Costa, B Ng, ... ACS Medicinal Chemistry Letters 6 (2), 216-220, 2015 | 22 | 2015 |
| Structure–activity studies of β-hairpin peptide inhibitors of the Plasmodium falciparum AMA1–RON2 interaction G Wang, N Drinkwater, DR Drew, CA MacRaild, DK Chalmers, B Mohanty, ... Journal of Molecular Biology 428 (20), 3986-3998, 2016 | 21 | 2016 |
| Determination of ligand binding modes in weak protein–ligand complexes using sparse NMR data B Mohanty, ML Williams, BC Doak, M Vazirani, O Ilyichova, G Wang, ... Journal of biomolecular NMR 66, 195-208, 2016 | 20 | 2016 |
| Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide G Wang, CA MacRaild, B Mohanty, M Mobli, NP Cowieson, RF Anders, ... PLoS One 9 (10), e109674, 2014 | 18 | 2014 |
| Detection and prevention of aggregation-based false positives in STD-NMR-based fragment screening A Vom, S Headey, G Wang, B Capuano, E Yuriev, MJ Scanlon, ... Australian Journal of Chemistry 66 (12), 1518-1524, 2013 | 17 | 2013 |
| Identification of the binding site of apical membrane antigen 1 (AMA1) inhibitors using a paramagnetic probe M Akter, N Drinkwater, SM Devine, SC Drew, B Krishnarjuna, CO Debono, ... ChemMedChem 14 (5), 603-612, 2019 | 13 | 2019 |
| Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens RP Smith, B Mohanty, S Mowlaboccus, JJ Paxman, ML Williams, ... Journal of Biological Chemistry 293 (43), 16559-16571, 2018 | 12 | 2018 |
| Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence … LF Duncan, G Wang, OV Ilyichova, R Dhouib, M Totsika, MJ Scanlon, ... Bioorganic & Medicinal Chemistry 45, 116315, 2021 | 8 | 2021 |
| Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities P Subedi, JJ Paxman, G Wang, L Hor, Y Hong, AD Verderosa, AE Whitten, ... Antioxidants & Redox Signaling 35 (1), 21-39, 2021 | 8 | 2021 |
| Structural bioinformatic analysis of DsbA proteins and their pathogenicity associated substrates C Santos-Martin, G Wang, P Subedi, L Hor, M Totsika, JJ Paxman, ... Computational and Structural Biotechnology Journal 19, 4725-4737, 2021 | 7 | 2021 |
| Methyl probes in proteins for determining ligand binding mode in weak protein–ligand complexes B Mohanty, J Orts, G Wang, S Nebl, WS Alwan, BC Doak, ML Williams, ... Scientific Reports 12 (1), 11231, 2022 | 4 | 2022 |
| Selective Binding of Small Molecules to Vibrio cholerae DsbA Offers a Starting Point for the Design of Novel Antibacterials G Wang, B Mohanty, ML Williams, BC Doak, R Dhouib, M Totsika, ... ChemMedChem 17 (6), e202100673, 2022 | 3 | 2022 |
| A Buried Water Network Modulates the Activity of the Escherichia coli Disulphide Catalyst DsbA G Wang, J Qin, AD Verderosa, L Hor, C Santos-Martin, JJ Paxman, ... Antioxidants 12 (2), 380, 2023 | | 2023 |
| Fragment-based development of bacterial DsbA inhibitors as novel anti-virulence agents G Wang, W Alwan, M Bentley, B Mohanty, B Doak, R Dhouib, M Totsika, ... Acta Crystallographica Section A: Foundations and Advances 77, C567-C567, 2021 | | 2021 |
Martin ScanlonProfessor of Medicinal Chemistry, Monash UniversityVerified email at monash.edu
