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Dr. Tyler Lalonde
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Learning from the past: possible urgent prevention and treatment options for severe acute respiratory infections caused by 2019‐nCoV
JS Morse, T Lalonde, S Xu, WR Liu
Chembiochem 21 (5), 730-738, 2020
9282020
Evidence supporting a role for the blood-cerebrospinal fluid barrier transporting circulating ghrelin into the brain
M Uriarte, PN De Francesco, G Fernandez, A Cabral, D Castrogiovanni, ...
Molecular neurobiology 56, 4120-4134, 2019
592019
Drug repurposing for the SARS‐CoV‐2 papain‐like protease
CC Cho, SG Li, TJ Lalonde, KS Yang, G Yu, Y Qiao, S Xu, W Ray Liu
ChemMedChem 17 (1), e202100455, 2022
332022
Changes in the cardiac GHSR1a-ghrelin system correlate with myocardial dysfunction in diabetic cardiomyopathy in mice
R Sullivan, R McGirr, S Hu, A Tan, D Wu, C Charron, T Lalonde, E Arany, ...
Journal of the Endocrine Society 2 (2), 178-189, 2018
212018
Dynamics of the ghrelin/growth hormone secretagogue receptor system in the human heart before and after cardiac transplantation
R Sullivan, VK Randhawa, A Stokes, D Wu, T Lalonde, B Kiaii, L Luyt, ...
Journal of the Endocrine Society 3 (4), 748-762, 2019
162019
Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor
MM Fowkes, T Lalonde, L Yu, S Dhanvantari, MS Kovacs, LG Luyt
European Journal of Medicinal Chemistry 157, 1500-1511, 2018
112018
Novel regioselective approach to cyclize phage-displayed peptides in combination with epitope-directed selection to identify a potent neutralizing macrocyclic peptide for SARS …
JT Hampton, TJ Lalonde, JM Tharp, Y Kurra, YR Alugubelli, CM Roundy, ...
ACS chemical biology 17 (10), 2911-2922, 2022
82022
Regional differences in the ghrelin-growth hormone secretagogue receptor signalling system in human heart disease
R Sullivan, VK Randhawa, T Lalonde, T Yu, B Kiaii, L Luyt, G Wisenberg, ...
CJC open 3 (2), 182-194, 2021
82021
The development of peptide–boron difluoride formazanate conjugates as fluorescence imaging agents
N Sharma, SM Barbon, T Lalonde, RR Maar, M Milne, JB Gilroy, LG Luyt
RSC advances 10 (32), 18970-18977, 2020
82020
Development and Characterization of an 18F-labeled Ghrelin Peptidomimetic for Imaging the Cardiac Growth Hormone Secretagogue Receptor
A Abbas, L Yu, T Lalonde, D Wu, JD Thiessen, LG Luyt, S Dhanvantari
Molecular Imaging 17, 1536012118809587, 2018
72018
Stapled ghrelin peptides as fluorescent imaging probes
T Lalonde, TG Shepherd, S Dhanvantari, LG Luyt
Peptide Science 111 (1), e24055, 2019
52019
Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019-nCoV. LID-10.26434/chemrxiv. 11728983. v1
JS Morse, T Lalonde, S Xu, WR Liu
32020
Single Amino Acid Replacement in G‐7039 Leads to a 70‐fold Increase in Binding toward GHS‐R1a
T Lalonde, MM Fowkes, J Hou, PE Thibeault, M Milne, S Dhanvantari, ...
ChemMedChem 14 (20), 1762-1766, 2019
32019
Expression of the growth hormone secretagogue receptor and ghrelin in human heart failure
R Sullivan, V Randhawa, A Stokes, S Liu, D Wu, C Charron, T Lalonde, ...
Canadian Journal of Cardiology 33 (10), S205-S206, 2017
22017
Ghrelin proteolysis increases in plasma of men, but not women, with obesity
AS Fittipaldi, D Castrogiovanni, D Lufrano, C Saenz, PN De Francesco, ...
Life Sciences 313, 121305, 2023
12023
Ghrelin and des-acyl ghrelin binding in cardiac tissue are altered with cardiovascular inflammation in Duchenne muscular dystrophy
M Naghibosadat, T Lalonde, L Luyt, L Hoffman, S Dhanvantari
Canadian Journal of Cardiology 34 (10), S33, 2018
12018
Drug Repurposing for the SARS-CoV-2 Papain-Like Protease (preprint)
CCD Cho, SG Li, KS Yang, TJ Lalonde, G Yu, Y Qiao, S Xu, WR Liu
2021
Learning from the
T Lalonde, S Xu, W Liu
2020
Front Cover: Single Amino Acid Replacement in G‐7039 Leads to a 70‐fold Increase in Binding toward GHS‐R1a (ChemMedChem 20/2019)
T Lalonde, MM Fowkes, J Hou, PE Thibeault, M Milne, S Dhanvantari, ...
ChemMedChem 14 (20), 1743-1743, 2019
2019
THE GROWTH HORMONE SECRETAGOGUE RECEPTOR, GHRELIN, AND BNP IN HUMAN HEART DISEASE WITH PRESERVED EJECTION FRACTION
R Sullivan, V Randhawa, T Lalonde, L Luyt, G Wisenberg, S Dhanvantari
Canadian Journal of Cardiology 35 (10), S112-S113, 2019
2019
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Articles 1–20