| TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates F Laferrière, Z Maniecka, M Pérez-Berlanga, M Hruska-Plochan, ... Nature neuroscience 22 (1), 65-77, 2019 | 149 | 2019 |
| A transgenic minipig model of Huntington's Disease M Baxa, M Hruska-Plochan, S Juhas, P Vodicka, A Pavlok, J Juhasova, ... Journal of Huntington's disease 2 (1), 47-68, 2013 | 149 | 2013 |
| Human neural stem cell replacement therapy for amyotrophic lateral sclerosis by spinal transplantation MP Hefferan, J Galik, O Kakinohana, G Sekerkova, C Santucci, S Marsala, ... Public Library of Science 7 (8), e42614, 2012 | 127 | 2012 |
| Macrophage migration inhibitory factor as a chaperone inhibiting accumulation of misfolded SOD1 A Israelson, D Ditsworth, S Sun, SW Song, J Liang, M Hruska-Plochan, ... Neuron 86 (1), 218-232, 2015 | 124 | 2015 |
| Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation S van Gorp, M Leerink, O Kakinohana, O Platoshyn, C Santucci, J Galik, ... Stem cell research & therapy 4, 1-22, 2013 | 118 | 2013 |
| Nuclear import receptors directly bind to arginine-rich dipeptide repeat proteins and suppress their pathological interactions S Hutten, S Usluer, B Bourgeois, F Simonetti, HM Odeh, CM Fare, ... Cell reports 33 (12), 2020 | 74 | 2020 |
| Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs A Miyanohara, K Kamizato, S Juhas, J Juhasova, M Navarro, S Marsala, ... Molecular Therapy Methods & Clinical Development 3, 2016 | 64 | 2016 |
| Pig models of neurodegenerative disorders: Utilization in cell replacement‐based preclinical safety and efficacy studies D Dolezalova, M Hruska‐Plochan, CR Bjarkam, JCH Sørensen, ... Journal of Comparative Neurology 522 (12), 2784-2801, 2014 | 57 | 2014 |
| Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS S Sahadevan, KM Hembach, E Tantardini, M Pérez-Berlanga, ... Nature Communications 12 (1), 3027, 2021 | 54 | 2021 |
| Hypertonic stress causes cytoplasmic translocation of neuronal, but not astrocytic, FUS due to impaired transportin function EM Hock, Z Maniecka, M Hruska-Plochan, S Reber, F Laferrière, SS MK, ... Cell reports 24 (4), 987-1000. e7, 2018 | 54 | 2018 |
| LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies M Emmenegger, E De Cecco, M Hruska‐Plochan, T Eninger, ... EMBO molecular medicine 13 (9), e14745, 2021 | 49 | 2021 |
| Survival of syngeneic and allogeneic iPSC–derived neural precursors after spinal grafting in minipigs J Strnadel, C Carromeu, C Bardy, M Navarro, O Platoshyn, AN Glud, ... Science translational medicine 10 (440), eaam6651, 2018 | 49 | 2018 |
| A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors D Bohaciakova, M Hruska-Plochan, R Tsunemoto, WD Gifford, SP Driscoll, ... Stem cell research & therapy 10, 1-19, 2019 | 38 | 2019 |
| Effective long-term immunosuppression in rats by subcutaneously implanted sustained-release tacrolimus pellet: effect on spinally grafted human neural precursor survival J Sevc, D Goldberg, S Van Gorp, M Leerink, S Juhas, J Juhasova, ... Experimental neurology 248, 85-99, 2013 | 29 | 2013 |
| Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells A Almenar-Queralt, D Merkurjev, HS Kim, M Navarro, Q Ma, RS Chaves, ... Nature genetics 51 (12), 1691-1701, 2019 | 26 | 2019 |
| New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseases. M Hruska-Plochan, B Li, D Kyburz, J Krützfeldt, U Landmesser, A Aguzzi, ... Swiss medical weekly 145, w14192, 2015 | 15 | 2015 |
| Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD M Hruska-Plochan, KM Betz, S Ronchi, VI Wiersma, Z Maniecka, EM Hock, ... bioRxiv, 2021.12. 08.471089, 2021 | 12 | 2021 |
| Loss of TDP‐43 oligomerization or RNA binding elicits distinct aggregation patterns M Pérez‐Berlanga, VI Wiersma, A Zbinden, L De Vos, U Wagner, ... The EMBO journal 42 (17), e111719, 2023 | 9 | 2023 |
| Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease M Jambeau, KD Meyer, M Hruska-Plochan, R Tabet, CZ Lee, A Ray-Soni, ... Proceedings of the National Academy of Sciences 119 (49), e2123487119, 2022 | 6 | 2022 |
| Time course of spinal doublecortin expression in developing rat and porcine spinal cord: implication in in vivo neural precursor grafting studies J Juhasova, S Juhas, M Hruska-Plochan, D Dolezalova, M Holubova, ... Cellular and molecular neurobiology 35, 57-70, 2015 | 6 | 2015 |
Martin Marsalauniversity of california, san diegoVerified email at health.ucsd.edu
