| Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation. HAL Bensaad K, Favaro E, Lewis CA, Peck B, Lord S, Collins JM, Pinnick KE ... Cell Reports 9 (1), 349-65, 2014 | 607 | 2014 |
| Cell-programmed nutrient partitioning in the tumour microenvironment BI Reinfeld, MZ Madden, MM Wolf, A Chytil, JE Bader, AR Patterson, ... Nature 593 (7858), 282-288, 2021 | 586 | 2021 |
| Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells CA Lewis, SJ Parker, BP Fiske, D McCloskey, DY Gui, CR Green, ... Molecular cell 55 (2), 253-263, 2014 | 579 | 2014 |
| Physiologic medium rewires cellular metabolism and reveals uric acid as an endogenous inhibitor of UMP synthase JR Cantor, M Abu-Remaileh, N Kanarek, E Freinkman, X Gao, ... Cell 169 (2), 258-272. e17, 2017 | 476 | 2017 |
| A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate ME Pacold, KR Brimacombe, SH Chan, JM Rohde, CA Lewis, ... Nature chemical biology 12 (6), 452-458, 2016 | 466 | 2016 |
| Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability MR Sullivan, LV Danai, CA Lewis, SH Chan, DY Gui, T Kunchok, ... Elife 8, e44235, 2019 | 403 | 2019 |
| Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours J Garcia-Bermudez, L Baudrier, K La, XG Zhu, J Fidelin, VO Sviderskiy, ... Nature cell biology 20 (7), 775-781, 2018 | 361 | 2018 |
| Metabolomics in cancer research and emerging applications in clinical oncology DR Schmidt, R Patel, DG Kirsch, CA Lewis, MG Vander Heiden, ... CA: a cancer journal for clinicians 71 (4), 333-358, 2021 | 354 | 2021 |
| Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons Y Li, H Wang, J Muffat, AW Cheng, DA Orlando, J Lovén, S Kwok, ... Cell stem cell 13 (4), 446-458, 2013 | 345 | 2013 |
| Fasting activates fatty acid oxidation to enhance intestinal stem cell function during homeostasis and aging MM Mihaylova, CW Cheng, AQ Cao, S Tripathi, MD Mana, ... Cell stem cell 22 (5), 769-778. e4, 2018 | 337 | 2018 |
| NUFIP1 is a ribosome receptor for starvation-induced ribophagy GA Wyant, M Abu-Remaileh, EM Frenkel, NN Laqtom, V Dharamdasani, ... Science 360 (6390), 751-758, 2018 | 315 | 2018 |
| Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death J Garcia-Bermudez, L Baudrier, EC Bayraktar, Y Shen, K La, ... Nature 567 (7746), 118-122, 2019 | 298 | 2019 |
| Aspartate is an endogenous metabolic limitation for tumour growth LB Sullivan, A Luengo, LV Danai, LN Bush, FF Diehl, AM Hosios, AN Lau, ... Nature cell biology 20 (7), 782-788, 2018 | 287 | 2018 |
| Increased demand for NAD+ relative to ATP drives aerobic glycolysis A Luengo, Z Li, DY Gui, LB Sullivan, M Zagorulya, BT Do, R Ferreira, ... Molecular cell 81 (4), 691-707. e6, 2021 | 286 | 2021 |
| Histidine catabolism is a major determinant of methotrexate sensitivity N Kanarek, HR Keys, JR Cantor, CA Lewis, SH Chan, T Kunchok, ... Nature 559 (7715), 632-636, 2018 | 274 | 2018 |
| Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition A Muir, LV Danai, DY Gui, CY Waingarten, CA Lewis, MG Vander Heiden Elife 6, e27713, 2017 | 271 | 2017 |
| Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth B Griffiths, CA Lewis, K Bensaad, S Ros, Q Zhang, EC Ferber, S Konisti, ... Cancer & metabolism 1, 1-21, 2013 | 256 | 2013 |
| SREBP maintains lipid biosynthesis and viability of cancer cells under lipid-and oxygen-deprived conditions and defines a gene signature associated with poor survival in … CA Lewis, C Brault, B Peck, K Bensaad, B Griffiths, R Mitter, ... Oncogene 34 (40), 5128-5140, 2015 | 222 | 2015 |
| Increased serine synthesis provides an advantage for tumors arising in tissues where serine levels are limiting MR Sullivan, KR Mattaini, EA Dennstedt, AA Nguyen, S Sivanand, ... Cell metabolism 29 (6), 1410-1421. e4, 2019 | 204 | 2019 |
| APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia G Sienski, P Narayan, JM Bonner, N Kory, S Boland, AA Arczewska, ... Science translational medicine 13 (583), eaaz4564, 2021 | 197 | 2021 |
