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William A. Chutkow
William A. Chutkow
Novartis Institure of Biomedical Research
Verified email at novartis.com
Title
Cited by
Cited by
Year
TXNIP regulates peripheral glucose metabolism in humans
H Parikh, E Carlsson, WA Chutkow, LE Johansson, H Storgaard, ...
PLoS medicine 4 (5), e158, 2007
5582007
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
S Shah, A Henry, C Roselli, H Lin, G Sveinbjörnsson, G Fatemifar, ...
Nature communications 11 (1), 163, 2020
5232020
The interaction of thioredoxin with Txnip: evidence for formation of a mixed disulfide by disulfide exchange
P Patwari, LJ Higgins, WA Chutkow, J Yoshioka, RT Lee
Journal of Biological Chemistry 281 (31), 21884-21891, 2006
3762006
Cloning, tissue expression, and chromosomal localization of SUR2, the putative drug-binding subunit of cardiac, skeletal muscle, and vascular KATP channels
WA Chutkow, MC Simon, MM Le Beau, CF Burant
Diabetes 45 (10), 1439-1445, 1996
3281996
Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 KATP channels
WA Chutkow, J Pu, MT Wheeler, T Wada, JC Makielski, CF Burant, ...
The Journal of clinical investigation 110 (2), 203-208, 2002
3082002
Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production
WA Chutkow, P Patwari, J Yoshioka, RT Lee
Journal of Biological Chemistry 283 (4), 2397-2406, 2008
2372008
Thioredoxin-independent regulation of metabolism by the α-arrestin proteins
P Patwari, WA Chutkow, K Cummings, VLRM Verstraeten, J Lammerding, ...
Journal of Biological Chemistry 284 (37), 24996-25003, 2009
2232009
Deletion of the α-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity
WA Chutkow, AL Birkenfeld, JD Brown, HY Lee, DW Frederick, ...
Diabetes 59 (6), 1424-1434, 2010
1832010
Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury
J Yoshioka, WA Chutkow, S Lee, JB Kim, J Yan, R Tian, ML Lindsey, ...
The Journal of clinical investigation 122 (1), 267-279, 2012
1822012
Disruption of Sur2-containing KATP channels enhances insulin-stimulated glucose uptake in skeletal muscle
WA Chutkow, V Samuel, PA Hansen, J Pu, CR Valdivia, JC Makielski, ...
Proceedings of the National Academy of Sciences 98 (20), 11760-11764, 2001
1502001
The arrestin domain-containing 3 protein regulates body mass and energy expenditure
P Patwari, V Emilsson, EE Schadt, WA Chutkow, S Lee, A Marsili, ...
Cell metabolism 14 (5), 671-683, 2011
1332011
Alternative splicing of sur2 Exon 17 regulates nucleotide sensitivity of the ATP-sensitive potassium channel
WA Chutkow, JC Makielski, DJ Nelson, CF Burant, Z Fan
Journal of Biological Chemistry 274 (19), 13656-13665, 1999
1241999
Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload
J Yoshioka, K Imahashi, SA Gabel, WA Chutkow, AA Burds, J Gannon, ...
Circulation research 101 (12), 1328-1338, 2007
1192007
Myocardial infarction triggers chronic cardiac autoimmunity in type 1 diabetes
RV Gottumukkala, HJ Lv, L Cornivelli, AJ Wagers, RY Kwong, R Bronson, ...
Science translational medicine 4 (138), 138ra80-138ra80, 2012
762012
The effects of licogliflozin, a dual SGLT1/2 inhibitor, on body weight in obese patients with or without diabetes
YL He, W Haynes, CD Meyers, A Amer, Y Zhang, P Mahling, ...
Diabetes, obesity and metabolism 21 (6), 1311-1321, 2019
722019
Thioredoxin Regulates Adipogenesis through Thioredoxin-interacting Protein (Txnip) Protein Stability*♦
WA Chutkow, RT Lee
Journal of Biological Chemistry 286 (33), 29139-29145, 2011
672011
Thioredoxin‐interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress
S Lee, S Min Kim, J Dotimas, L Li, EP Feener, S Baldus, RB Myers, ...
EMBO molecular medicine 6 (6), 732-743, 2014
542014
A crisis in late pregnancy
AS Desai, WA Chutkow, E Edelman, KE Economy, GW Dec Jr
New England Journal of Medicine 361 (23), 2271-2277, 2009
422009
Evidence of K-ATP channels in native cardiac cells without SUR.
JL Pu, T Wada, C Valdivia, WA Chutkow, CF Burant, JC Makielski
Biophysical Journal 80 (1), 625A-626A, 2001
172001
Aptamer proteomics for biomarker discovery in heart failure with reduced ejection fraction
L Zhang, JW Cunningham, BL Claggett, J Jacob, MM Mendelson, ...
Circulation 146 (18), 1411-1414, 2022
122022
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