Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic S Jimenez, D Baglietto-Vargas, C Caballero, I Moreno-Gonzalez, ... Journal of Neuroscience 28 (45), 11650-11661, 2008 | 447 | 2008 |
The phenotype of soluble starch synthase IV defective mutants of Arabidopsis thaliana suggests a novel function of elongation enzymes in the control of starch … I Roldán, F Wattebled, M Mercedes Lucas, D Delvallé, V Planchot, ... The Plant Journal 49 (3), 492-504, 2007 | 306 | 2007 |
Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1× APP transgenic model of Alzheimer's disease B Ramos, D Baglietto-Vargas, JC del Rio, I Moreno-Gonzalez, ... Neurobiology of aging 27 (11), 1658-1672, 2006 | 253 | 2006 |
Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus R Sanchez-Varo, L Trujillo-Estrada, E Sanchez-Mejias, M Torres, ... Acta neuropathologica 123, 53-70, 2012 | 243 | 2012 |
Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease A Boza-Serrano, R Ruiz, R Sanchez-Varo, J García-Revilla, Y Yang, ... Acta neuropathologica 138, 251-273, 2019 | 222 | 2019 |
Age-dependent accumulation of soluble amyloid β (Aβ) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-α (sAPPα) by modulating … S Jimenez, M Torres, M Vizuete, R Sanchez-Varo, E Sanchez-Mejias, ... Journal of Biological Chemistry 286 (21), 18414-18425, 2011 | 220 | 2011 |
Microglia in Alzheimer’s disease: activated, dysfunctional or degenerative V Navarro, E Sanchez-Mejias, S Jimenez, C Muñoz-Castro, ... Frontiers in aging neuroscience 10, 357752, 2018 | 209 | 2018 |
Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration E Sanchez-Mejias, V Navarro, S Jimenez, M Sanchez-Mico, ... Acta neuropathologica 132, 897-916, 2016 | 156 | 2016 |
Calretinin interneurons are early targets of extracellular amyloid-β pathology in PS1/AβPP Alzheimer mice hippocampus D Baglietto-Vargas, I Moreno-Gonzalez, R Sanchez-Varo, S Jimenez, ... Journal of Alzheimer's disease 21 (1), 119-132, 2010 | 109 | 2010 |
Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP … M Torres, S Jimenez, R Sanchez-Varo, V Navarro, L Trujillo-Estrada, ... Molecular Neurodegeneration 7, 1-15, 2012 | 105 | 2012 |
Age‐related increase in the immunoproteasome content in rat hippocampus: molecular and functional aspects MP Gavilán, A Castaño, M Torres, M Portavella, C Caballero, S Jiménez, ... Journal of neurochemistry 108 (1), 260-272, 2009 | 86 | 2009 |
Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology AM Fernandez, S Jimenez, M Mecha, D Davila, C Guaza, J Vitorica, ... Molecular psychiatry 17 (7), 705-718, 2012 | 78 | 2012 |
Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition M Paz Gavilan, C Pintado, E Gavilán, S Jiménez, RM Ríos, J Vitorica, ... Aging cell 8 (6), 654-665, 2009 | 71 | 2009 |
Extracellular amyloid-β and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1 M146L/APP 751SL mice I Moreno-Gonzalez, D Baglietto-Vargas, R Sanchez-Varo, S Jimenez, ... Journal of Alzheimer's Disease 18 (4), 755-776, 2009 | 62 | 2009 |
Cytomegalovirus infection in HIV-infected patients in the era of combination antiretroviral therapy R Perello, A Vergara, E Monclus, S Jimenez, M Montero, N Saubi, ... BMC Infectious diseases 19, 1-6, 2019 | 51 | 2019 |
Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease MV Sanchez‐Mico, S Jimenez, A Gomez‐Arboledas, C Muñoz‐Castro, ... Glia 69 (4), 997-1011, 2021 | 50 | 2021 |
Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death P Carriba, S Jimenez, V Navarro, I Moreno-Gonzalez, ... Cell death & disease 6 (2), e1639-e1639, 2015 | 46 | 2015 |
In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology L Trujillo-Estrada, S Jimenez, V De Castro, M Torres, D Baglietto-Vargas, ... Acta Neuropathologica Communications 1, 1-16, 2013 | 45 | 2013 |
Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model JJ Fernandez-Valenzuela, R Sanchez-Varo, C Muñoz-Castro, ... Scientific reports 10 (1), 14776, 2020 | 44 | 2020 |
Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease D Baglietto-Vargas, E Sánchez-Mejias, V Navarro, S Jimenez, ... Scientific Reports 7 (1), 10085, 2017 | 40 | 2017 |