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Sebastián Jiménez
Sebastián Jiménez
Universidad de Sevilla
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Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic
S Jimenez, D Baglietto-Vargas, C Caballero, I Moreno-Gonzalez, ...
Journal of Neuroscience 28 (45), 11650-11661, 2008
4472008
The phenotype of soluble starch synthase IV defective mutants of Arabidopsis thaliana suggests a novel function of elongation enzymes in the control of starch …
I Roldán, F Wattebled, M Mercedes Lucas, D Delvallé, V Planchot, ...
The Plant Journal 49 (3), 492-504, 2007
3062007
Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1× APP transgenic model of Alzheimer's disease
B Ramos, D Baglietto-Vargas, JC del Rio, I Moreno-Gonzalez, ...
Neurobiology of aging 27 (11), 1658-1672, 2006
2532006
Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus
R Sanchez-Varo, L Trujillo-Estrada, E Sanchez-Mejias, M Torres, ...
Acta neuropathologica 123, 53-70, 2012
2432012
Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
A Boza-Serrano, R Ruiz, R Sanchez-Varo, J García-Revilla, Y Yang, ...
Acta neuropathologica 138, 251-273, 2019
2222019
Age-dependent accumulation of soluble amyloid β (Aβ) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-α (sAPPα) by modulating …
S Jimenez, M Torres, M Vizuete, R Sanchez-Varo, E Sanchez-Mejias, ...
Journal of Biological Chemistry 286 (21), 18414-18425, 2011
2202011
Microglia in Alzheimer’s disease: activated, dysfunctional or degenerative
V Navarro, E Sanchez-Mejias, S Jimenez, C Muñoz-Castro, ...
Frontiers in aging neuroscience 10, 357752, 2018
2092018
Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration
E Sanchez-Mejias, V Navarro, S Jimenez, M Sanchez-Mico, ...
Acta neuropathologica 132, 897-916, 2016
1562016
Calretinin interneurons are early targets of extracellular amyloid-β pathology in PS1/AβPP Alzheimer mice hippocampus
D Baglietto-Vargas, I Moreno-Gonzalez, R Sanchez-Varo, S Jimenez, ...
Journal of Alzheimer's disease 21 (1), 119-132, 2010
1092010
Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP …
M Torres, S Jimenez, R Sanchez-Varo, V Navarro, L Trujillo-Estrada, ...
Molecular Neurodegeneration 7, 1-15, 2012
1052012
Age‐related increase in the immunoproteasome content in rat hippocampus: molecular and functional aspects
MP Gavilán, A Castaño, M Torres, M Portavella, C Caballero, S Jiménez, ...
Journal of neurochemistry 108 (1), 260-272, 2009
862009
Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology
AM Fernandez, S Jimenez, M Mecha, D Davila, C Guaza, J Vitorica, ...
Molecular psychiatry 17 (7), 705-718, 2012
782012
Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition
M Paz Gavilan, C Pintado, E Gavilán, S Jiménez, RM Ríos, J Vitorica, ...
Aging cell 8 (6), 654-665, 2009
712009
Extracellular amyloid-β and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1 M146L/APP 751SL mice
I Moreno-Gonzalez, D Baglietto-Vargas, R Sanchez-Varo, S Jimenez, ...
Journal of Alzheimer's Disease 18 (4), 755-776, 2009
622009
Cytomegalovirus infection in HIV-infected patients in the era of combination antiretroviral therapy
R Perello, A Vergara, E Monclus, S Jimenez, M Montero, N Saubi, ...
BMC Infectious diseases 19, 1-6, 2019
512019
Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease
MV Sanchez‐Mico, S Jimenez, A Gomez‐Arboledas, C Muñoz‐Castro, ...
Glia 69 (4), 997-1011, 2021
502021
Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death
P Carriba, S Jimenez, V Navarro, I Moreno-Gonzalez, ...
Cell death & disease 6 (2), e1639-e1639, 2015
462015
In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology
L Trujillo-Estrada, S Jimenez, V De Castro, M Torres, D Baglietto-Vargas, ...
Acta Neuropathologica Communications 1, 1-16, 2013
452013
Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model
JJ Fernandez-Valenzuela, R Sanchez-Varo, C Muñoz-Castro, ...
Scientific reports 10 (1), 14776, 2020
442020
Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease
D Baglietto-Vargas, E Sánchez-Mejias, V Navarro, S Jimenez, ...
Scientific Reports 7 (1), 10085, 2017
402017
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