Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior T Sakurai, A Amemiya, M Ishii, I Matsuzaki, RM Chemelli, H Tanaka, ... Cell 92 (4), 573-585, 1998 | 6488 | 1998 |
GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition AG Gilmartin, MR Bleam, A Groy, KG Moss, EA Minthorn, SG Kulkarni, ... Clinical cancer research 17 (5), 989-1000, 2011 | 676 | 2011 |
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase R Verma, RS Annan, MJ Huddleston, SA Carr, G Reynard, RJ Deshaies Science 278 (5337), 455-460, 1997 | 636 | 1997 |
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway P Chaturvedi, WK Eng, Y Zhu, MR Mattern, R Mishra, MR Hurle, X Zhang, ... Oncogene 18 (28), 4047-4054, 1999 | 559 | 1999 |
Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL L Liu, J Greger, H Shi, Y Liu, J Greshock, R Annan, W Halsey, GM Sathe, ... Cancer research 69 (17), 6871-6878, 2009 | 555 | 2009 |
Selective detection and sequencing of phosphopeptides at the femtomole level by mass spectrometry SA Carr, MJ Huddleston, RS Annan Analytical biochemistry 239 (2), 180-192, 1996 | 453 | 1996 |
Hydrophilic interaction chromatography reduces the complexity of the phosphoproteome and improves global phosphopeptide isolation and detection DE McNulty, RS Annan Molecular & cellular proteomics 7 (5), 971-980, 2008 | 444 | 2008 |
Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase Y Chi, MJ Huddleston, X Zhang, RA Young, RS Annan, SA Carr, ... Genes & development 15 (9), 1078-1092, 2001 | 410 | 2001 |
Phosphopeptide analysis by matrix-assisted laser desorption time-of-flight mass spectrometry RS Annan, SA Carr Analytical Chemistry 68 (19), 3413-3421, 1996 | 397 | 1996 |
Selective detection of phosphopeptides in complex mixtures by electrospray liquid chromatography/mass spectrometry MJ Huddleston, RS Annan, MF Bean, SA Carr Journal of the American Society for Mass Spectrometry 4 (9), 710-717, 1993 | 312 | 1993 |
Examination of micro-tip reversed-phase liquid chromatographic extraction of peptide pools for mass spectrometric analysis H Erdjument-Bromage, M Lui, L Lacomis, A Grewal, RS Annan, ... Journal of Chromatography A 826 (2), 167-181, 1998 | 258 | 1998 |
Phosphorylation by cyclin B-Cdk underlies release of mitotic exit activator Cdc14 from the nucleolus R Azzam, SL Chen, W Shou, AS Mah, G Alexandru, K Nasmyth, ... Science 305 (5683), 516-519, 2004 | 250 | 2004 |
Anti-tumor activity of the type I PRMT inhibitor, GSK3368715, synergizes with PRMT5 inhibition through MTAP loss A Fedoriw, SR Rajapurkar, S O'Brien, SV Gerhart, LH Mitchell, ND Adams, ... Cancer cell 36 (1), 100-114. e25, 2019 | 231 | 2019 |
Antitumor activity of an allosteric inhibitor of centromere-associated protein-E KW Wood, L Lad, L Luo, X Qian, SD Knight, N Nevins, K Brejc, D Sutton, ... Proceedings of the National Academy of Sciences 107 (13), 5839-5844, 2010 | 229 | 2010 |
A multidimensional electrospray MS-based approach to phosphopeptide mapping RS Annan, MJ Huddleston, R Verma, RJ Deshaies, SA Carr Analytical chemistry 73 (3), 393-404, 2001 | 218 | 2001 |
Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells J Billiard, JB Dennison, J Briand, RS Annan, D Chai, M Colón, ... Cancer & metabolism 1, 1-17, 2013 | 211 | 2013 |
Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation GS Van Aller, N Reynoird, O Barbash, M Huddleston, S Liu, AF Zmoos, ... Epigenetics 7 (4), 340-343, 2012 | 207 | 2012 |
Cell cycle regulation of myosin-V by calcium/calmodulin-dependent protein kinase II RL Karcher, JT Roland, F Zappacosta, MJ Huddleston, RS Annan, ... Science 293 (5533), 1317-1320, 2001 | 174 | 2001 |
Calmodulin modulates the interaction between IQGAP1 and Cdc42: identification of IQGAP1 by nanoelectrospray tandem mass spectrometry JL Joyal, RS Annan, YD Ho, ME Huddleston, SA Carr, MJ Hart, DB Sacks Journal of Biological Chemistry 272 (24), 15419-15425, 1997 | 169 | 1997 |
Mammalian homologues of the Drosophila slit protein are ligands of the heparan sulfate proteoglycan glypican-1 in brain Y Liang, RS Annan, SA Carr, S Popp, M Mevissen, RK Margolis, ... Journal of Biological Chemistry 274 (25), 17885-17892, 1999 | 167 | 1999 |