| Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate NC Hait, J Allegood, M Maceyka, GM Strub, KB Harikumar, SK Singh, ... Science 325 (5945), 1254-1257, 2009 | 1097 | 2009 |
| Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2 SE Alvarez, KB Harikumar, NC Hait, J Allegood, GM Strub, EY Kim, ... Nature 465 (7301), 1084-1088, 2010 | 864 | 2010 |
| SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism M Maceyka, H Sankala, NC Hait, H Le Stunff, H Liu, R Toman, C Collier, ... Journal of Biological Chemistry 280 (44), 37118-37129, 2005 | 746 | 2005 |
| Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases NC Hait, CA Oskeritzian, SW Paugh, S Milstien, S Spiegel Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (12), 2016-2026, 2006 | 622 | 2006 |
| Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer J Liang, M Nagahashi, EY Kim, KB Harikumar, A Yamada, WC Huang, ... Cancer cell 23 (1), 107-120, 2013 | 583 | 2013 |
| Extracellular and intracellular actions of sphingosine-1-phosphate GM Strub, M Maceyka, NC Hait, S Milstien, S Spiegel Sphingolipids as signaling and regulatory molecules, 141-155, 2010 | 413 | 2010 |
| Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration GM Strub, M Paillard, J Liang, L Gomez, JC Allegood, NC Hait, ... The FASEB Journal 25 (2), 600, 2011 | 399 | 2011 |
| Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2 K Takabe, RH Kim, JC Allegood, P Mitra, S Ramachandran, M Nagahashi, ... Journal of Biological Chemistry 285 (14), 10477-10486, 2010 | 307 | 2010 |
| Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells S Sarkar, M Maceyka, NC Hait, SW Paugh, H Sankala, S Milstien, ... FEBS letters 579 (24), 5313-5317, 2005 | 271 | 2005 |
| Sphingosine-1-phosphate signaling in immune cells and inflammation: roles and therapeutic potential M Aoki, H Aoki, R Ramanathan, NC Hait, K Takabe Mediators of inflammation 2016, 2016 | 236 | 2016 |
| Targeting sphingosine kinase 1 inhibits Akt signaling, induces apoptosis, and suppresses growth of human glioblastoma cells and xenografts D Kapitonov, JC Allegood, C Mitchell, NC Hait, JA Almenara, JK Adams, ... Cancer research 69 (17), 6915-6923, 2009 | 226 | 2009 |
| Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory NC Hait, LE Wise, JC Allegood, M O'brien, D Avni, TM Reeves, PE Knapp, ... Nature neuroscience 17 (7), 971-980, 2014 | 215 | 2014 |
| A novel salt-tolerant L-myo-inositol-1-phosphate synthase from Porteresia coarctata (Roxb.) Tateoka, a halophytic wild rice: molecular cloning, bacterial overexpression … M Majee, S Maitra, KG Dastidar, S Pattnaik, A Chatterjee, NC Hait, ... Journal of Biological Chemistry 279 (27), 28539-28552, 2004 | 213 | 2004 |
| Sphingosine kinase type 2 activation by ERK-mediated phosphorylation NC Hait, A Bellamy, S Milstien, T Kordula, S Spiegel Journal of Biological Chemistry 282 (16), 12058-12065, 2007 | 205 | 2007 |
| Role of sphingosine kinase 2 in cell migration toward epidermal growth factor NC Hait, S Sarkar, H Le Stunff, A Mikami, M Maceyka, S Milstien, ... Journal of Biological Chemistry 280 (33), 29462-29469, 2005 | 204 | 2005 |
| Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin HM Sankala, NC Hait, SW Paugh, D Shida, S Lépine, LW Elmore, P Dent, ... Cancer research 67 (21), 10466-10474, 2007 | 193 | 2007 |
| Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression M Nagahashi, K Takabe, R Liu, K Peng, X Wang, Y Wang, NC Hait, ... Hepatology 61 (4), 1216-1226, 2015 | 183 | 2015 |
| Targeting the SphK1/S1P/S1PR1 axis that links obesity, chronic inflammation, and breast cancer metastasis M Nagahashi, A Yamada, E Katsuta, T Aoyagi, WC Huang, KP Terracina, ... Cancer research 78 (7), 1713-1725, 2018 | 182 | 2018 |
| The role of sphingosine-1-phosphate and ceramide-1-phosphate in inflammation and cancer NC Hait, A Maiti Mediators of inflammation 2017, 2017 | 179 | 2017 |
| Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network M Nagahashi, EY Kim, A Yamada, S Ramachandran, JC Allegood, ... The FASEB Journal 27 (3), 1001, 2013 | 173 | 2013 |
