| One-Pot Synthesis of Benzo[b]furan and Indole Inhibitors of Tubulin Polymerization BL Flynn, E Hamel, MK Jung Journal of medicinal chemistry 45 (12), 2670-2673, 2002 | 346 | 2002 |
| A Novel Palladium-Mediated Coupling Approach to 2,3-Disubstituted Benzo[b]thiophenes and Its Application to the Synthesis of Tubulin Binding Agents BL Flynn, P Verdier-Pinard, E Hamel Organic Letters 3 (5), 651-654, 2001 | 280 | 2001 |
| Iodine-induced reaction cascades for the rapid construction of variously substituted benzothiophenes KO Hessian, BL Flynn Organic Letters 5 (23), 4377-4380, 2003 | 204 | 2003 |
| The synthesis and tubulin binding activity of thiophene-based analogues of combretastatin A-4 BL Flynn, GP Flynn, E Hamel, MK Jung Bioorganic & Medicinal Chemistry Letters 11 (17), 2341-2343, 2001 | 178 | 2001 |
| Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative … BL Flynn, GS Gill, DW Grobelny, JH Chaplin, D Paul, AF Leske, ... Journal of medicinal chemistry 54 (17), 6014-6027, 2011 | 164 | 2011 |
| Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome NN Jimenez-Vargas, LA Pattison, P Zhao, TM Lieu, R Latorre, DD Jensen, ... Proceedings of the National Academy of Sciences 115 (31), E7438-E7447, 2018 | 150 | 2018 |
| Selective endo and exo iodocyclizations in the synthesis of quinolines and indoles KO Hessian, BL Flynn Organic Letters 8 (2), 243-246, 2006 | 136 | 2006 |
| Allosteric Modulators of the Adenosine A1 Receptor: Synthesis and Pharmacological Evaluation of 4-Substituted 2-Amino-3-benzoylthiophenes L Aurelio, C Valant, BL Flynn, PM Sexton, A Christopoulos, PJ Scammells Journal of medicinal chemistry 52 (14), 4543-4547, 2009 | 133 | 2009 |
| Palladium-catalyzed coupling of terminal alkynes with 5-(trifluoromethanesulfonyloxy) pyrimidine nucleosides GT Crisp, BL Flynn The Journal of Organic Chemistry 58 (24), 6614-6619, 1993 | 128 | 1993 |
| The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4 DJ Kerr, E Hamel, MK Jung, BL Flynn Bioorganic & medicinal chemistry 15 (9), 3290-3298, 2007 | 120 | 2007 |
| BNC105: a novel tubulin polymerization inhibitor that selectively disrupts tumor vasculature and displays single-agent antitumor efficacy G Kremmidiotis, AF Leske, TC Lavranos, D Beaumont, J Gasic, A Hall, ... Molecular cancer therapeutics 9 (6), 1562-1573, 2010 | 104 | 2010 |
| Selective Cleavage of Isopropyl Aryl Ethers by Aluminum Trichloride† MG Banwell, BL Flynn, SG Stewart The Journal of Organic Chemistry 63 (24), 9139-9144, 1998 | 98 | 1998 |
| Multicomponent coupling approach to (±)-frondosin B and a ring-expanded analogue DJ Kerr, AC Willis, BL Flynn Organic Letters 6 (4), 457-460, 2004 | 96 | 2004 |
| Convergent syntheses of the pyrrolic marine natural products lamellarin-O, lamellarin-Q, lukianol-A and some more highly oxygenated congeners MG Banwell, BL Flynn, DCR Hockless Chemical Communications, 207-208, 1997 | 77 | 1997 |
| From sphingosine kinase to dihydroceramide desaturase: a structure–activity relationship (SAR) study of the enzyme inhibitory and anticancer activity of 4-((4-(4-chlorophenyl … L Aurelio, CV Scullino, MR Pitman, A Sexton, V Oliver, L Davies, ... Journal of medicinal chemistry 59 (3), 965-984, 2016 | 69 | 2016 |
| Alternating iodonium-mediated reaction cascades giving indole-and quinoline-containing polycycles R Halim, PJ Scammells, BL Flynn Organic Letters 10 (10), 1967-1970, 2008 | 69 | 2008 |
| Solid-Phase Synthesis of 2,3-Disubstituted Benzo[b]thiophenes and Benzo[b]selenophenes CT Bui, BL Flynn Journal of Combinatorial Chemistry 8 (2), 163-167, 2006 | 65 | 2006 |
| 2-Aminothienopyridazines as Novel Adenosine A1 Receptor Allosteric Modulators and Antagonists GN Ferguson, C Valant, J Horne, H Figler, BL Flynn, J Linden, ... Journal of medicinal chemistry 51 (19), 6165-6172, 2008 | 63 | 2008 |
| Oxazolidinone-promoted, torquoselective nazarov cyclizations DJ Kerr, M Miletic, JH Chaplin, JM White, BL Flynn Organic letters 14 (7), 1732-1735, 2012 | 62 | 2012 |
| 5-Substituted 2-aminothiophenes as A1 adenosine receptor allosteric enhancers L Aurelio, H Figler, BL Flynn, J Linden, PJ Scammells Bioorganic & medicinal chemistry 16 (3), 1319-1327, 2008 | 60 | 2008 |
