Design, computational studies, synthesis and biological evaluation of thiazole-based molecules as anticancer agents S Patel, R Patle, P Parameswaran, A Jain, A Shard European Journal of Pharmaceutical Sciences 134, 20-30, 2019 | 51 | 2019 |
Scope of successive C–H functionalizations of the methyl group in 3-picolines: intramolecular carbonylation of arenes to the metal-free synthesis of 4-azafluorenones JK Laha, KP Jethava, S Patel Organic letters 17 (23), 5890-5893, 2015 | 49 | 2015 |
Intramolecular acylation of unactivated pyridines or arenes via multiple C–H functionalizations: Synthesis of all four azafluorenones and fluorenones JK Laha, KP Jethava, S Patel, KV Patel The Journal of Organic Chemistry 82 (1), 76-85, 2017 | 35 | 2017 |
A perspective on synthesis and applications of fluorenones S Patel, B Rathod, S Regu, S Chak, A Shard ChemistrySelect 5 (34), 10673-10691, 2020 | 28 | 2020 |
Novel imidazopyrimidines-based molecules induce tetramerization of tumor pyruvate kinase M2 and exhibit potent antiproliferative profile S Patel, C Globisch, P Pulugu, P Kumar, A Jain, A Shard European Journal of Pharmaceutical Sciences 170, 106112, 2022 | 22 | 2022 |
Potassium tert-butoxide mediated C–C, C–N, C–O and C–S bond forming reactions J Madasu, S Shinde, R Das, S Patel, A Shard Organic & Biomolecular Chemistry 18 (41), 8346-8365, 2020 | 22 | 2020 |
Pyruvate kinase M2 in chronic inflammations: a potpourri of crucial protein–protein interactions S Patel, A Das, P Meshram, A Sharma, A Chowdhury, H Jariyal, A Datta, ... Cell biology and toxicology 37, 653-678, 2021 | 18 | 2021 |
Drug development and bioanalytical method validation for a novel anticancer molecule, 4‐(dimethylamino)‐2‐(p‐tolylamino) thiazole‐5‐carbonitrile NM Biswas, A Shard, S Patel, P Sengupta Drug development research 79 (8), 391-399, 2018 | 18 | 2018 |
Tumor pyruvate kinase M2 modulators: a comprehensive account of activators and inhibitors as anticancer agents B Rathod, S Chak, S Patel, A Shard RSC Medicinal Chemistry 12 (7), 1121-1141, 2021 | 17 | 2021 |
A perspective on environmentally benign protocols of thiazole synthesis A Chowdhury, S Patel, A Sharma, A Das, P Meshram, A Shard Chemistry of Heterocyclic Compounds 56, 455-463, 2020 | 17 | 2020 |
Boronic acid derivative activates pyruvate kinase M2 indispensable for redox metabolism in oral cancer cells M Rihan, LV Nalla, A Dharavath, S Patel, A Shard, A Khairnar Bioorganic & Medicinal Chemistry Letters 59, 128539, 2022 | 12 | 2022 |
Metabolite profiling of IMID‐2, a novel anticancer molecule of piperazine derivative: In silico prediction, in vitro and in vivo metabolite characterization using UPLC … NK Panday, D Thakkar, S Patel, A Shard, P Sengupta Biomedical Chromatography 35 (6), e5082, 2021 | 12 | 2021 |
Discovery of boronic acid-based potent activators of tumor pyruvate kinase M2 and development of gastroretentive nanoformulation for oral dosing R Patle, S Shinde, S Patel, R Maheshwari, H Jariyal, A Srivastava, ... Bioorganic & Medicinal Chemistry Letters 42, 128062, 2021 | 9 | 2021 |
A Series of Ferrocene-Containing Pyrazolo[1,5-a]pyrimidines Induce a Strong Antiproliferative Effect against Oral Cancer Cells A Gupta, R Das, A Chamoli, A Choithramani, H Kumar, S Patel, D Khude, ... Organometallics 41 (16), 2365-2378, 2022 | 6 | 2022 |
Direct Deoxygenative Intramolecular Acylation of Biarylcarboxylic Acids Y Li, W Xu, C Zhu, J Xie Synlett 32 (04), 387-390, 2021 | 5 | 2021 |
Objective assessment of adrenocortical carcinoma driver genes and their correlation with tumor pyruvate kinase M2 R Das, MG Chowdhury, S Raundal, J Jadhav, N Kumar, S Patel, A Shard Gene 822, 146354, 2022 | 3 | 2022 |
Palladium-Catalysed Coupling and Acid-Mediated Cyclisation: Synthesis of Fluorenones and Fluorenes DR Kumar, DR Kishore, G Satyanarayana SynOpen 2 (04), 0268-0275, 2018 | 3 | 2018 |
Dendronized polymeric biomaterial for loading, stabilization, and targeted cytosolic delivery of microRNA in cancer cells V Tambe, S Patel, A Shard, SK Behera, S Polaka, N Anup, A Gadeval, ... ACS Applied Bio Materials 5 (9), 4128-4153, 2022 | 2 | 2022 |
Assessment of metabolic stability and pharmacokinetics by LC–MS/MS and establishment of the safe dose of IMID‐2, a novel anticancer molecule under drug discovery SP Kumar, T Jadav, AK Sahu, M Ghosh Chowdhary, A Siwach, H Patel, ... Biomedical Chromatography 37 (6), e5618, 2023 | 1 | 2023 |
Design and synthesis of novel quinazolinone-based pyruvate kinase M2 activators as selective inhibitors of oral cancer cells B Rathod, S Joshi, S Regu, K Manikanta, H Kumar, S Dubey, ... Journal of Molecular Structure 1304, 137595, 2024 | | 2024 |