Intercalators as anticancer drugs MF Brana, M Cacho, A Gradillas, B Pascual-Teresa, A Ramos Current pharmaceutical design 7 (17), 1745-1780, 2001 | 621 | 2001 |
Control of the exo and endo Pathways of the Diels-Alder Reaction by Antibody Catalysis VE Gouverneur, KN Houk, B de Pascual-Teresa, B Beno, KD Janda, ... Science 262 (5131), 204-208, 1993 | 306 | 1993 |
Potential anti-inflammatory, anti-adhesive, anti/estrogenic, and angiotensin-converting enzyme inhibitory activities of anthocyanins and their gut metabolites M Hidalgo, S Martin-Santamaria, I Recio, C Sanchez-Moreno, ... Genes & nutrition 7, 295-306, 2012 | 191 | 2012 |
New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties MF Braña, M Cacho, MA García, B de Pascual-Teresa, A Ramos, ... Journal of medicinal chemistry 47 (6), 1391-1399, 2004 | 143 | 2004 |
Synthesis and DNA binding properties of γ-carbolinium derivatives and benzologues A Molina, JJ Vaquero, JL Garcia-Navio, J Alvarez-Builla, ... The Journal of Organic Chemistry 61 (16), 5587-5599, 1996 | 110 | 1996 |
Pyrazolo[3,4-c]pyridazines as Novel and Selective Inhibitors of Cyclin-Dependent Kinases MF Braña, M Cacho, ML García, EP Mayoral, B López, ... Journal of medicinal chemistry 48 (22), 6843-6854, 2005 | 96 | 2005 |
Targeting matrix metalloproteinases: exploring the dynamics of the S1′ pocket in the design of selective, small molecule inhibitors: miniperspective B Fabre, A Ramos, B de Pascual-Teresa Journal of medicinal chemistry 57 (24), 10205-10219, 2014 | 95 | 2014 |
Azino-fused benzimidazolium salts as DNA intercalating agents. 2. J Pastor, JG Siro, JL García-Navío, JJ Vaquero, J Alvarez-Builla, F Gago, ... The Journal of Organic Chemistry 62 (16), 5476-5483, 1997 | 71 | 1997 |
Synthesis, antitumor activity, molecular modeling, and DNA binding properties of a new series of imidazonaphthalimides MF Braña, M Cacho, MA García, B de Pascual-Teresa, A Ramos, N Acero, ... Journal of medicinal chemistry 45 (26), 5813-5816, 2002 | 67 | 2002 |
Structure–affinity relationships for the binding of actinomycin D to DNA J Gallego, AR Ortiz, B de Pascual-Teresa, F Gago Journal of computer-aided molecular design 11, 114-128, 1997 | 54 | 1997 |
Structure of micelle‐bound adrenomedullin: A first step toward the analysis of its interactions with receptors and small molecules J Pérez‐Castells, S Martín‐Santamaría, L Nieto, A Ramos, A Martínez, ... Biopolymers 97 (1), 45-53, 2012 | 50 | 2012 |
Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities M Julián, M Cacho, MA García, S Martín-Santamaría, ... European journal of medicinal chemistry 40 (8), 737-750, 2005 | 50 | 2005 |
Assessment of solvation effects on calculated binding affinity differences: trypsin inhibition by flavonoids as a model system for congeneric series. A Checa, AR Ortiz, B de Pascual-Teresa, F Gago Journal of medicinal chemistry 40 (25), 4136-4145, 1997 | 50 | 1997 |
Novel DNA Intercalators Based on the Pyridazino[1‘,6‘:1,2]pyrido[4,3-b]indol-5-inium System A Molina, JJ Vaquero, JL Garcia-Navio, J Alvarez-Builla, ... The Journal of Organic Chemistry 64 (11), 3907-3915, 1999 | 48 | 1999 |
Synthesis and biological evaluation of analogues of butyrolactone I and molecular model of its interaction with CDK2 MF Braña, ML García, B López, B de Pascual-Teresa, A Ramos, ... Organic & biomolecular chemistry 2 (13), 1864-1871, 2004 | 47 | 2004 |
Potent “clicked” MMP2 inhibitors: synthesis, molecular modeling and biological exploration JM Zapico, P Serra, J García-Sanmartín, K Filipiak, RJ Carbajo, AK Schott, ... Organic & Biomolecular Chemistry 9 (12), 4587-4599, 2011 | 46 | 2011 |
Molecular imaging probes based on matrix metalloproteinase inhibitors (MMPIs) L Rangasamy, B Di Geronimo, I Ortín, C Coderch, JM Zapico, A Ramos, ... Molecules 24 (16), 2982, 2019 | 42 | 2019 |
Progress towards water-soluble triazole-based selective MMP-2 inhibitors B Fabre, K Filipiak, JM Zapico, N Díaz, RJ Carbajo, AK Schott, ... Organic & Biomolecular Chemistry 11 (38), 6623-6641, 2013 | 39 | 2013 |
FJ Cañada, M. Menéndez, O. Ramström, J. Jiménez-Barbero, D. Solís and H.-J. Gabius S Martín-Santamaría, S André, E Buzamet, R Caraballo, ... Org. Biomol. Chem 9, 5445-5455, 2011 | 39 | 2011 |
Adrenomedullin: a new and promising target for drug discovery MA Garcia, S Martín-Santamaría, B de Pascual-Teresa, A Ramos, ... Expert opinion on therapeutic targets 10 (2), 303-317, 2006 | 39 | 2006 |