Non-classical transpeptidases yield insight into new antibacterials P Kumar, A Kaushik, EP Lloyd, SG Li, R Mattoo, NC Ammerman, DT Bell, ... Nature chemical biology 13 (1), 54-61, 2017 | 127 | 2017 |
A Novel Small-Molecule Inhibitor of the Mycobacterium tuberculosis Demethylmenaquinone Methyltransferase MenG Is Bactericidal to Both Growing and Nutritionally Deprived … P Sukheja, P Kumar, N Mittal, SG Li, E Singleton, R Russo, AL Perryman, ... mBio 8 (1), e02022-16, 2017 | 78 | 2017 |
Mycobacterium abscessus L, D-transpeptidases are susceptible to inactivation by carbapenems and cephalosporins but not penicillins P Kumar, V Chauhan, JRA Silva, J Lameira, FB d'Andrea, SG Li, SL Ginell, ... Antimicrobial agents and chemotherapy 61 (10), e00866-17, 2017 | 63 | 2017 |
A Virtual Screen Discovers Novel, Fragment-Sized Inhibitors of Mycobacterium tuberculosis InhA AL Perryman, W Yu, X Wang, S Ekins, S Forli, SG Li, JS Freundlich, ... Journal of chemical information and modeling 55 (3), 645-659, 2015 | 44 | 2015 |
Synergistic lethality of a binary inhibitor of Mycobacterium tuberculosis KasA P Kumar, GC Capodagli, D Awasthi, R Shrestha, K Maharaja, P Sukheja, ... MBio 9 (6), e02101-17, 2018 | 38 | 2018 |
A High Throughput Screening Assay for Anti-Mycobacterial small molecules based on adenylate kinase release as a reporter of cell lysis L Forbes, K Ebsworth-Mojica, L DiDone, SG Li, JS Freundlich, N Connell, ... PloS one 10 (6), e0129234, 2015 | 30 | 2015 |
Evolution of a thienopyrimidine antitubercular relying on medicinal chemistry and metabolomics insights SG Li, C Vilchèze, S Chakraborty, X Wang, H Kim, M Anisetti, S Ekins, ... Tetrahedron letters 56 (23), 3246-3250, 2015 | 30 | 2015 |
Antitubercular triazines: Optimization and intrabacterial metabolism X Wang, D Inoyama, R Russo, SG Li, R Jadhav, TP Stratton, N Mittal, ... Cell chemical biology 27 (2), 172-185. e11, 2020 | 26 | 2020 |
A preclinical candidate targeting Mycobacterium tuberculosis KasA D Inoyama, D Awasthi, GC Capodagli, K Tsotetsi, P Sukheja, ... Cell chemical biology 27 (5), 560-570. e10, 2020 | 23 | 2020 |
Combining metabolite-based pharmacophores with bayesian machine learning models for Mycobacterium tuberculosis drug discovery S Ekins, PB Madrid, M Sarker, SG Li, N Mittal, P Kumar, X Wang, ... PloS one 10 (10), e0141076, 2015 | 21 | 2015 |
Intrabacterial Metabolism Obscures the Successful Prediction of an InhA Inhibitor of Mycobacterium tuberculosis X Wang, AL Perryman, SG Li, SD Paget, TP Stratton, A Lemenze, ... ACS infectious diseases 5 (12), 2148-2163, 2019 | 19 | 2019 |
Mixed-valent manganese phosphonate clusters prepared under microwave-assisted and ambient conditions JT Li, YS Ma, SG Li, DK Cao, YZ Li, Y Song, LM Zheng Dalton Transactions, 5029-5034, 2009 | 17 | 2009 |
Addressing the Metabolic Stability of Antituberculars through Machine Learning TP Stratton, AL Perryman, C Vilchèze, R Russo, SG Li, JS Patel, ... ACS Medicinal Chemistry Letters 8 (10), 1099-1104, 2017 | 16 | 2017 |
Synthesis and Absolute Configuration of Demethyl (C‐11) Cezomycin SG Li, Y Wu Chemistry–An Asian Journal 8 (11), 2792-2800, 2013 | 14 | 2013 |
Facile Conversion of Cyclopropanols into Linear Conjugate Enones WB Han, SG Li, XW Lu, Y Wu European Journal of Organic Chemistry 2014 (18), 3841-3846, 2014 | 12 | 2014 |
Metagenome‐Guided Analogue Synthesis Yields Improved Gram‐Negative‐Active Albicidin‐and Cystobactamid‐Type Antibiotics Z Wang, A Kasper, R Mehmood, M Ternei, S Li, JS Freundlich, SF Brady Angewandte Chemie 133 (41), 22346-22351, 2021 | 11 | 2021 |
A Novel Allyl Transfer Coupled with a Grob Fragmentation SG Li, HJ Chen, YY Yang, WJ Wu, Y Wu Chemistry–An Asian Journal 10 (11), 2333-2336, 2015 | 8 | 2015 |
Regio-selective reduction of the C–C double bonds in α, β-unsaturated acyl 4-substituted oxazolidin-2-ones and oxazolidine-2-thiones SG Li, JW Jin, Y Wu Tetrahedron 68 (3), 846-850, 2012 | 6 | 2012 |
A Novel Oral GyrB/ParE Dual Binding Inhibitor Effective against Multidrug-Resistant Neisseria gonorrhoeae and Other High-Threat Pathogens S Park, R Russo, L Westfall, R Shrestha, M Zimmerman, V Dartois, ... Antimicrobial Agents and Chemotherapy 66 (9), e00414-22, 2022 | 3 | 2022 |
Chaperone therapy for mucopolysaccharidosis type IIIC AV Pshezhetsky, X Pan, R Héon-Roberts, SG Li, HY Wu, M Taherzadeh, ... Molecular Genetics and Metabolism 123 (2), S121-S122, 2018 | 2 | 2018 |