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Kristian Helin
Kristian Helin
Verified email at icr.ac.uk - Homepage
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Cited by
Year
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
K Agger, PAC Cloos, J Christensen, D Pasini, S Rose, J Rappsilber, ...
Nature 449 (7163), 731-734, 2007
15312007
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
AP Bracken, N Dietrich, D Pasini, KH Hansen, K Helin
Genes & development 20 (9), 1123-1136, 2006
15262006
EZH2 is downstream of the pRB‐E2F pathway, essential for proliferation and amplified in cancer
AP Bracken, D Pasini, M Capra, E Prosperini, E Colli, K Helin
The EMBO journal, 2003
14462003
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
K Williams, J Christensen, MT Pedersen, JV Johansen, PAC Cloos, ...
Nature 473 (7347), 343-348, 2011
10972011
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
D Pasini, AP Bracken, MR Jensen, EL Denchi, K Helin
The EMBO journal 23 (20), 4061-4071, 2004
10692004
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
AP Bracken, D Kleine-Kohlbrecher, N Dietrich, D Pasini, G Gargiulo, ...
Genes & development 21 (5), 525-530, 2007
10252007
Molecular mechanisms and potential functions of histone demethylases
SM Kooistra, K Helin
Nature reviews Molecular cell biology 13 (5), 297-311, 2012
9902012
Role of TET enzymes in DNA methylation, development, and cancer
KD Rasmussen, K Helin
Genes & development 30 (7), 733-750, 2016
9842016
Transcriptional regulation by Polycomb group proteins
L Di Croce, K Helin
Nature structural & molecular biology 20 (10), 1147-1155, 2013
9542013
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis
H Müller, AP Bracken, R Vernell, MC Moroni, F Christians, E Grassilli, ...
Genes & development 15 (3), 267-285, 2001
9372001
The putative oncogene GASC1 demethylates tri-and dimethylated lysine 9 on histone H3
PAC Cloos, J Christensen, K Agger, A Maiolica, J Rappsilber, T Antal, ...
Nature 442 (7100), 307-311, 2006
8862006
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
K Helin, JA Lees, M Vidal, N Dyson, E Harlow, A Fattaey
Cell 70 (2), 337-350, 1992
8231992
A model for transmission of the H3K27me3 epigenetic mark
KH Hansen, AP Bracken, D Pasini, N Dietrich, SS Gehani, A Monrad, ...
Nature cell biology 10 (11), 1291-1300, 2008
8182008
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
PAC Cloos, J Christensen, K Agger, K Helin
Genes & development 22 (9), 1115-1140, 2008
8042008
The polycomb group protein Suz12 is required for embryonic stem cell differentiation
D Pasini, AP Bracken, JB Hansen, M Capillo, K Helin
Molecular and cellular biology, 2007
8042007
Apaf-1 is a transcriptional target for E2F and p53
MC Moroni, ES Hickman, EL Denchi, G Caprara, E Colli, F Cecconi, ...
Nature cell biology 3 (6), 552-558, 2001
7982001
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ...
Cancer cell 24 (5), 660-672, 2013
7402013
Polycomb group proteins: navigators of lineage pathways led astray in cancer
AP Bracken, K Helin
Nature Reviews Cancer 9 (11), 773-784, 2009
6992009
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein
K Helin, ED Harlow, A Fattaey
Molecular and cellular biology 13 (10), 6501-6508, 1993
6961993
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.
L Zhu, S van den Heuvel, K Helin, A Fattaey, M Ewen, D Livingston, ...
Genes & development 7 (7a), 1111-1125, 1993
6791993
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