Directed differentiation of cholangiocytes from human pluripotent stem cells M Ogawa, S Ogawa, CE Bear, S Ahmadi, S Chin, B Li, M Grompe, ... Nature biotechnology 33 (8), 853-861, 2015 | 305 | 2015 |
VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface PDW Eckford, M Ramjeesingh, S Molinski, S Pasyk, JF Dekkers, C Li, ... Chemistry & biology 21 (5), 666-678, 2014 | 113 | 2014 |
Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue SV Molinski, S Ahmadi, W Ip, H Ouyang, A Villella, JP Miller, PS Lee, ... EMBO molecular medicine 9 (9), 1224-1243, 2017 | 107 | 2017 |
Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia S Ahmadi, Z Bozoky, M Di Paola, S Xia, C Li, AP Wong, L Wellhauser, ... NPJ genomic medicine 2 (1), 12, 2017 | 69 | 2017 |
Synergy of cAMP and calcium signaling pathways in CFTR regulation Z Bozoky, S Ahmadi, T Milman, TH Kim, K Du, M Di Paola, S Pasyk, ... Proceedings of the national academy of sciences 114 (11), E2086-E2095, 2017 | 64 | 2017 |
Functional rescue of F508del-CFTR using small molecule correctors S Molinski, PDW Eckford, S Pasyk, S Ahmadi, S Chin, CE Bear Frontiers in pharmacology 3, 160, 2012 | 54 | 2012 |
SLC6A14 Is a Genetic Modifier of Cystic Fibrosis That Regulates Pseudomonas aeruginosa Attachment to Human Bronchial Epithelial Cells M Di Paola, AJ Park, S Ahmadi, EJ Roach, YS Wu, M Struder-Kypke, ... MBio 8 (6), 10.1128/mbio. 02073-17, 2017 | 48 | 2017 |
Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms T Beaudoin, TA Stone, M Glibowicka, C Adams, Y Yau, S Ahmadi, ... Scientific reports 8 (1), 14728, 2018 | 47 | 2018 |
ORKAMBI-mediated rescue of mucociliary clearance in cystic fibrosis primary respiratory cultures is enhanced by arginine uptake, arginase inhibition, and promotion of nitric … YS Wu, J Jiang, S Ahmadi, A Lew, O Laselva, S Xia, C Bartlett, W Ip, ... Molecular Pharmacology 96 (4), 515-525, 2019 | 46 | 2019 |
Facilitating structure-function studies of CFTR modulator sites with efficiencies in mutagenesis and functional screening SV Molinski, S Ahmadi, M Hung, CE Bear Journal of biomolecular screening 20 (10), 1204-1217, 2015 | 45 | 2015 |
Sphingosine-1-phosphate is a novel regulator of cystic fibrosis transmembrane conductance regulator (CFTR) activity FA Malik, A Meissner, I Semenkov, S Molinski, S Pasyk, S Ahmadi, HH Bui, ... PLoS One 10 (6), e0130313, 2015 | 44 | 2015 |
Lipophilicity of the cystic fibrosis drug, ivacaftor (VX-770), and its destabilizing effect on the major CF-causing mutation: F508del S Chin, M Hung, A Won, YS Wu, S Ahmadi, D Yang, S Elmallah, K Toutah, ... Molecular pharmacology 94 (2), 917-925, 2018 | 39 | 2018 |
SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion S Ahmadi, S Xia, YS Wu, M Di Paola, R Kissoon, C Luk, F Lin, K Du, ... Elife 7, e37963, 2018 | 36 | 2018 |
The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation S Pasyk, S Molinski, S Ahmadi, M Ramjeesingh, LJ Huan, S Chin, K Du, ... Proteomics 15 (2-3), 447-461, 2015 | 31 | 2015 |
Conformational defects underlie proteasomal degradation of Dent's disease-causing mutants of ClC-5 C D’Antonio, S Molinski, S Ahmadi, LJ Huan, L Wellhauser, CE Bear Biochemical Journal 452 (3), 391-400, 2013 | 25 | 2013 |
Inhalational anesthetics induce neuronal protein aggregation and affect ER trafficking M Coghlan, E Richards, S Shaik, P Rossi, RB Vanama, S Ahmadi, ... Scientific Reports 8 (1), 5275, 2018 | 15 | 2018 |
An organoid model to assay the role of CFTR in the human epididymis epithelium SH Leir, S Yin, JL Kerschner, S Xia, S Ahmadi, C Bear, A Harris Cell and tissue research 381, 327-336, 2020 | 14 | 2020 |
Augmentation of cystic fibrosis transmembrane conductance regulator function in human bronchial epithelial cells via SLC6A14-dependent amino acid uptake. Implications for … S Ahmadi, YS Wu, M Li, W Ip, A Lloyd-Kuzik, M Di Paola, K Du, S Xia, ... American journal of respiratory cell and molecular biology 61 (6), 755-764, 2019 | 14 | 2019 |
Differential diagnosis of pediatric multiple sclerosis MM Galardi, C Gaudioso, S Ahmadi, E Evans, L Gilbert, S Mar Children 6 (6), 75, 2019 | 14 | 2019 |
Conversion of human and mouse fibroblasts into lung-like epithelial cells AP Wong, S Shojaie, Q Liang, S Xia, M Di Paola, S Ahmadi, C Bilodeau, ... Scientific reports 9 (1), 9027, 2019 | 12 | 2019 |