The NF-κB family of transcription factors and its regulation A Oeckinghaus, S Ghosh Cold Spring Harbor perspectives in biology 1 (4), a000034, 2009 | 3099 | 2009 |
Crosstalk in NF-κB signaling pathways A Oeckinghaus, MS Hayden, S Ghosh Nature immunology 12 (8), 695-708, 2011 | 2054 | 2011 |
A20 negatively regulates T cell receptor signaling to NF-κB by cleaving Malt1 ubiquitin chains M Düwel, V Welteke, A Oeckinghaus, M Baens, B Kloo, U Ferch, ... The journal of immunology 182 (12), 7718-7728, 2009 | 266 | 2009 |
Malt1 ubiquitination triggers NF‐κB signaling upon T‐cell activation A Oeckinghaus, E Wegener, V Welteke, U Ferch, SÇ Arslan, J Ruland, ... The EMBO journal 26 (22), 4634-4645, 2007 | 245 | 2007 |
IκBβ acts to inhibit and activate gene expression during the inflammatory response P Rao, MS Hayden, M Long, ML Scott, AP West, D Zhang, A Oeckinghaus, ... Nature 466 (7310), 1115-1119, 2010 | 208 | 2010 |
Essential role for IκB kinase β in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation E Wegener, A Oeckinghaus, N Papadopoulou, L Lavitas, ... Molecular cell 23 (1), 13-23, 2006 | 167 | 2006 |
Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ... Cancer cell 38 (2), 198-211. e8, 2020 | 130 | 2020 |
Alternative splicing of MALT1 controls signalling and activation of CD4+ T cells I Meininger, RA Griesbach, D Hu, T Gehring, T Seeholzer, A Bertossi, ... Nature communications 7 (1), 11292, 2016 | 103 | 2016 |
Crystal Structure of F-93 from Sulfolobus Spindle-Shaped Virus 1, a Winged-Helix DNA Binding Protein P Kraft, A Oeckinghaus, D Kümmel, GH Gauss, J Gilmore, B Wiedenheft, ... Journal of virology 78 (21), 11544-11550, 2004 | 55 | 2004 |
Structure of D-63 from Sulfolobus spindle-shaped virus 1: surface properties of the dimeric four-helix bundle suggest an adaptor protein function P Kraft, D Kümmel, A Oeckinghaus, GH Gauss, B Wiedenheft, M Young, ... Journal of virology 78 (14), 7438-7442, 2004 | 48 | 2004 |
κB-Ras proteins regulate both NF-κB-dependent inflammation and Ral-dependent proliferation A Oeckinghaus, TS Postler, P Rao, H Schmitt, V Schmitt, ... Cell reports 8 (6), 1793-1807, 2014 | 37 | 2014 |
Distinct isocomplexes of the TRAPP trafficking factor coexist inside human cells D Kümmel, A Oeckinghaus, C Wang, D Krappmann, U Heinemann FEBS letters 582 (27), 3729-3733, 2008 | 36 | 2008 |
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation K Fitzian, A Brückner, L Brohée, R Zech, C Antoni, S Kiontke, R Gasper, ... Molecular cell 81 (13), 2705-2721. e8, 2021 | 31 | 2021 |
Structure of the tuberous sclerosis complex 2 (TSC2) N terminus provides insight into complex assembly and tuberous sclerosis pathogenesis R Zech, S Kiontke, U Mueller, A Oeckinghaus, D Kümmel Journal of Biological Chemistry 291 (38), 20008-20020, 2016 | 30 | 2016 |
κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis S Beel, L Kolloch, LH Apken, L Jürgens, A Bolle, N Sudhof, S Ghosh, ... Nature communications 11 (1), 3409, 2020 | 28 | 2020 |
Structure of the TSC2 GAP domain: mechanistic insight into catalysis and pathogenic mutations P Hansmann, A Brückner, S Kiontke, B Berkenfeld, G Seebohm, ... Structure 28 (8), 933-942. e4, 2020 | 21 | 2020 |
The RAL signaling network: Cancer and beyond LH Apken, A Oeckinghaus International Review of Cell and Molecular Biology 361, 21-105, 2021 | 15 | 2021 |
Impact of the nuclear envelope on malignant transformation, motility, and survival of lung cancer cells ST Stefanello, I Luchtefeld, I Liashkovich, Z Pethö, I Azzam, E Bulk, ... Advanced Science 8 (22), 2102757, 2021 | 12 | 2021 |
Control of expression of key cell cycle enzymes drives cell line-specific functions of CDK7 in human PDAC cells L Kolloch, T Kreinest, M Meisterernst, A Oeckinghaus International Journal of Molecular Sciences 23 (2), 812, 2022 | 9 | 2022 |
A pan-cancer analysis implicates human NKIRAS1 as a tumor-suppressor gene TS Postler, A Wang, FG Brundu, P Wang, Z Wu, KE Butler, ... Proceedings of the National Academy of Sciences 120 (46), e2312595120, 2023 | 1 | 2023 |