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Sergio Roa
Sergio Roa
Cima Universidad de Navarra
Verified email at unav.es
Title
Cited by
Cited by
Year
The biochemistry of somatic hypermutation
JU Peled, FL Kuang, MD Iglesias-Ussel, S Roa, SL Kalis, MF Goodman, ...
Annu. Rev. Immunol. 26, 481-511, 2008
6312008
Intraclonal complexity in chronic lymphocytic leukemia: fractions enriched in recently born/divided and older/quiescent cells
C Calissano, RN Damle, S Marsilio, XJ Yan, S Yancopoulos, G Hayes, ...
Molecular medicine 17, 1374-1382, 2011
2052011
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies
E San José-Enériz, X Agirre, O Rabal, A Vilas-Zornoza, JA Sanchez-Arias, ...
Nature communications 8 (1), 15424, 2017
1402017
Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression
S Roa, E Avdievich, JU Peled, T MacCarthy, U Werling, FL Kuang, R Kan, ...
Proceedings of the National Academy of Sciences 105 (42), 16248-16253, 2008
1252008
The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination
S Ramachandran, R Chahwan, RM Nepal, D Frieder, S Panier, S Roa, ...
Proceedings of the National Academy of Sciences 107 (2), 809-814, 2010
872010
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
JMM Van Oers, S Roa, U Werling, Y Liu, J Genschel, H Hou Jr, RS Sellers, ...
Proceedings of the National Academy of Sciences 107 (30), 13384-13389, 2010
852010
Quantitative analysis of bcl-2 expression in normal and leukemic human B-cell differentiation
P Menendez, A Vargas, C Bueno, S Barrena, J Almeida, M De Santiago, ...
Leukemia 18 (3), 491-498, 2004
852004
Downregulation of FOXP1 is required during germinal center B-cell function
A Sagardoy, JI Martinez-Ferrandis, S Roa, KL Bunting, MA Aznar, ...
Blood, The Journal of the American Society of Hematology 121 (21), 4311-4320, 2013
832013
Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes
S Schaetzlein, R Chahwan, E Avdievich, S Roa, K Wei, RL Eoff, ...
Proceedings of the National Academy of Sciences 110 (27), E2470-E2479, 2013
802013
IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions
PEM Patten, CC Chu, E Albesiano, RN Damle, XJ Yan, D Kim, L Zhang, ...
Blood, The Journal of the American Society of Hematology 120 (24), 4802-4811, 2012
752012
AIDing antibody diversity by error-prone mismatch repair
R Chahwan, W Edelmann, MD Scharff, S Roa
Seminars in immunology 24 (4), 293-300, 2012
722012
PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas
M Pascual, M Mena-Varas, EF Robles, MJ Garcia-Barchino, C Panizo, ...
Blood, The Journal of the American Society of Hematology 133 (22), 2401-2412, 2019
662019
LITAF, a BCL6 target gene, regulates autophagy in mature B‐cell lymphomas
C Bertolo, S Roa, A Sagardoy, M Mena‐Varas, EF Robles, ...
British journal of haematology 162 (5), 621-630, 2013
582013
miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma
N Bartolome-Izquierdo, VG de Yebenes, AF Alvarez-Prado, SM Mur, ...
Blood, The Journal of the American Society of Hematology 129 (17), 2408-2419, 2017
572017
Germline deletion of Igh 3′ regulatory region elements hs 5, 6, 7 (hs5–7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus
SA Volpi, J Verma-Gaur, R Hassan, Z Ju, S Roa, S Chatterjee, U Werling, ...
The Journal of Immunology 188 (6), 2556-2566, 2012
552012
Crosstalk between genetic and epigenetic information through cytosine deamination
R Chahwan, SN Wontakal, S Roa
Trends in genetics 26 (10), 443-448, 2010
522010
MSH2/MSH6 complex promotes error-free repair of AID-induced dU: G mispairs as well as error-prone hypermutation of A: T sites
S Roa, Z Li, JU Peled, C Zhao, W Edelmann, MD Scharff
PloS one 5 (6), e11182, 2010
522010
Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics
EF Robles, M Mena-Varas, L Barrio, SV Merino-Cortes, P Balogh, MQ Du, ...
Nature communications 7 (1), 11889, 2016
502016
The multidimensional nature of epigenetic information and its role in disease
R Chahwan, SN Wontakal, S Roa
Discovery medicine 11 (58), 233-243, 2011
502011
SHMTool: a webserver for comparative analysis of somatic hypermutation datasets
T MacCarthy, S Roa, MD Scharff, A Bergman
DNA repair 8 (1), 137-141, 2009
482009
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