DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway R Singh, PK Dhanyamraju, M Lauth Oncotarget 8 (1), 833, 2017 | 75 | 2017 |
Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1 P Schneider, J Miguel Bayo-Fina, R Singh, P Kumar Dhanyamraju, P Holz, ... Nature communications 6 (1), 8023, 2015 | 61 | 2015 |
Histone deacetylase 6 represents a novel drug target in the oncogenic Hedgehog signaling pathway PK Dhanyamraju, PS Holz, F Finkernagel, V Fendrich, M Lauth Molecular cancer therapeutics 14 (3), 727-739, 2015 | 57 | 2015 |
The Yes-associated protein controls the cell density regulation of Hedgehog signaling M Tariki, PK Dhanyamraju, V Fendrich, T Borggrefe, G Feldmann, M Lauth Oncogenesis 3 (8), e112-e112, 2014 | 52 | 2014 |
Drug-tolerant persister cells in cancer therapy resistance PK Dhanyamraju, TD Schell, S Amin, GP Robertson Cancer research 82 (14), 2503-2514, 2022 | 44 | 2022 |
Ikaros tumor suppressor function includes induction of active enhancers and super-enhancers along with pioneering activity Y Ding, B Zhang, JL Payne, C Song, Z Ge, C Gowda, S Iyer, ... Leukemia 33 (11), 2720-2731, 2019 | 35 | 2019 |
IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymphoblastic leukemia C Song, Z Ge, Y Ding, BH Tan, D Desai, K Gowda, S Amin, R Gowda, ... Blood, The Journal of the American Society of Hematology 136 (13), 1520-1534, 2020 | 32 | 2020 |
Melanoma therapeutics: a literature review PK Dhanyamraju, TN Patel Journal of biomedical research 36 (2), 77, 2022 | 23 | 2022 |
Cellular signaling and epigenetic regulation of gene expression in leukemia C Gowda, C Song, Y Ding, S Iyer, PK Dhanyamraju, M McGrath, ... Advances in biological regulation 75, 100665, 2020 | 23 | 2020 |
The PI3K/AKT pathway inhibitor ISC-4 induces apoptosis and inhibits growth of leukemia in preclinical models of acute myeloid leukemia C Annageldiyev, SF Tan, S Thakur, PK Dhanyamraju, SR Ramisetti, ... Frontiers in Oncology 10, 393, 2020 | 19 | 2020 |
Cell-free fetal DNA testing and its correlation with prenatal indications J Wang, Y Lyu, B Qiao, Y Li, Y Zhang, PK Dhanyamraju, Y Bamme, ... BMC Pregnancy and Childbirth 21 (1), 585, 2021 | 16 | 2021 |
Dual targeting of MTOR as a novel therapeutic approach for high-risk B-cell acute lymphoblastic leukemia Z Ge, C Song, Y Ding, BH Tan, D Desai, A Sharma, R Gowda, F Yue, ... Leukemia 35 (5), 1267-1278, 2021 | 10 | 2021 |
mechanistic basis for in vivo therapeutic efficacy of CK2 inhibitor CX-4945 in acute myeloid leukemia M Klink, MA Rahman, C Song, PK Dhanyamraju, M Ehudin, Y Ding, ... Cancers 13 (5), 1127, 2021 | 10 | 2021 |
Transcriptional regulation of genes by ikaros tumor suppressor in acute lymphoblastic leukemia PK Dhanyamraju, S Iyer, G Smink, Y Bamme, P Bhadauria, JL Payne, ... International journal of molecular sciences 21 (4), 1377, 2020 | 10 | 2020 |
Medulloblastoma:“Onset of the molecular era” PK Dhanyamraju, TN Patel, S Dovat Molecular Biology Reports 47 (12), 9931-9937, 2020 | 8 | 2020 |
Role of aberrant Sonic hedgehog signaling pathway in cancers and developmental anomalies TN Patel, PK Dhanyamraju Journal of biomedical research 36 (1), 1, 2022 | 6 | 2022 |
Transcriptional regulation of PIK3CD and PIKFYVE in T-cell acute lymphoblastic leukemia by IKAROS and protein kinase CK2 E Dovat, C Song, T Hu, MA Rahman, PK Dhanyamraju, M Klink, ... International journal of molecular sciences 22 (2), 819, 2021 | 6 | 2021 |
Targeting protein translation in melanoma by inhibiting EEF-2 kinase regulates cholesterol metabolism though SREBP2 to inhibit tumour development SS Dinavahi, YC Chen, R Gowda, PK Dhanyamraju, K Punnath, D Desai, ... International journal of molecular sciences 23 (7), 3481, 2022 | 5 | 2022 |
Regulation of small GTPase Rab20 by ikaros in B-cell acute lymphoblastic leukemia JL Payne, C Song, Y Ding, PK Dhanyamraju, Y Bamme, JW Schramm, ... International journal of molecular sciences 21 (5), 1718, 2020 | 5 | 2020 |
Revisiting the melanomagenic pathways and current therapeutic approaches PK Dhanyamraju, S Rotimi, P Bhattacharya, TN Patel Molecular Biology Reports 49 (10), 9651-9671, 2022 | 2 | 2022 |