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Prerna Sharma
Prerna Sharma
Geisinger Commonwealth School of Medicine
Verified email at som.geisinger.edu
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Year
Mycobacterium tuberculosis acquires iron by cell-surface sequestration and internalization of human holo-transferrin
VM Boradia, H Malhotra, JS Thakkar, VA Tillu, B Vuppala, P Patil, ...
Nature communications 5 (1), 4730, 2014
1042014
The Achilles’ Heel of “Ultrastable” hyperthermophile proteins: submillimolar concentrations of SDS stimulate rapid conformational change, aggregation, and amyloid formation in …
JM Khan, P Sharma, K Arora, N Kishor, P Kaila, P Guptasarma
Biochemistry 55 (28), 3920-3936, 2016
312016
Calcium binding to beta-2-microglobulin at physiological pH drives the occurrence of conformational changes which cause the protein to precipitate into amorphous forms that …
S Kumar, P Sharma, K Arora, M Raje, P Guptasarma
PLoS One 9 (4), e95725, 2014
242014
Development of biotransformation process for asymmetric reduction with novel anti-Prelog NADH-dependent alcohol dehydrogenases
S Shah, R Agera, P Sharma, AV Sunder, H Singh, HM James, ...
Process biochemistry 70, 71-78, 2018
232018
‘Super-perfect’enzymes: Structural stabilities and activities of recombinant triose phosphate isomerases from Pyrococcus furiosus and Thermococcus onnurineus produced in …
P Sharma, P Guptasarma
Biochemical and Biophysical Research Communications 460 (3), 753-758, 2015
182015
Creation of active TIM barrel enzymes through genetic fusion of half‐barrel domain constructs derived from two distantly related glycosyl hydrolases
P Sharma, P Kaila, P Guptasarma
The FEBS journal 283 (23), 4340-4356, 2016
122016
Design of novel cyanovirin-N variants by modulation of binding dynamics through distal mutations
IC Kazan, P Sharma, MI Rahman, A Bobkov, R Fromme, G Ghirlanda, ...
Elife 11, e67474, 2022
72022
Endoglucanase activity at a second site in Pyrococcus furiosus triosephosphate isomerase—Promiscuity or compensation for a metabolic handicap?
P Sharma, P Guptasarma
FEBS Open bio 7 (8), 1126-1143, 2017
62017
Pre-micellar concentrations of sodium dodecylbenzene sulphonate induce amyloid-like fibril formation in myoglobin at pH 4.5
JM Khan, A Malik, MA Khan, P Sharma, P Sen
Colloids and Surfaces A: Physicochemical and Engineering Aspects 586, 124240, 2020
52020
Therapeutic Antibodies in Medicine
P Sharma, RV Joshi, R Pritchard, K Xu, MA Eicher
Molecules 28 (18), 6438, 2023
42023
Hexametaphosphate, a Common Food Additive, Aggregated the Hen Egg White Lysozyme
A Malik, JM Khan, AM Al-Amri, N Altwaijry, P Sharma, A Alhomida, P Sen
ACS omega 8 (46), 44086-44092, 2023
32023
Interaction Mechanism between α-Lactalbumin and Caffeic Acid: A Multispectroscopic and Molecular Docking Study
NA Al-Shabib, JM Khan, AM Al-Amri, A Malik, FM Husain, P Sharma, ...
ACS omega 8 (22), 19853–19861, 2023
32023
Examining the effect of removing a conserved disulfide bond on the structural stability and activity of a lysozyme-specific nanobody
P Sharma, PN Enick
PROTEIN SCIENCE 32 (12), 2023
2023
Anionic surfactant causes dual conformational changes in insulin
JM Khan, A Malik, P Sharma, S Fatima
International Journal of Biological Macromolecules 247, 125790, 2023
2023
Core Concepts as a Framework to Assess the Progression of Student Learning in a Ume Curriculum
D Averill, GN Waite, P Sharma, S Mamillapalli, C Carbe
The FASEB Journal 36, 2022
2022
Design of novel CV-N variants: Modulation of binding dynamics through distal mutations
IC Kazan, P Sharma, A Bobkov, R Fromme, G Ghirlanda, SB Ozkan
bioRxiv, 2020.12. 21.423842, 2020
2020
Liquid-Liquid Phase Separation of Intrinsically Disordered Proteins for Development of Membraneless Organelles in Synthetic Cells
M Costantino, P Sharma, SM Vaiana, G Ghirlanda
Biophysical Journal 118 (3), 213a, 2020
2020
DESIGN OF NOVEL LECTINS BY COMPUTER-AIDED DIRECTED EVOLUTION
P Sharma, IC Kazan, SB Ozkan, G Ghirlanda
PROTEIN SCIENCE 28, 81-81, 2019
2019
Design of Novel Lectins by Computer‐Guided Directed Evolution
P Sharma, IC Kazan, SB Ozkan, G Ghirlanda
The FASEB Journal 32, 673.24-673.24, 2018
2018
Engineering Targeted Lectins by Computer-Guided Directed Evolution
IC Kazan, P Sharma
Biophysical Journal 114 (3), 223a, 2018
2018
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