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Xuming Tang
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A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids
L Yang, Y Han, BE Nilsson-Payant, V Gupta, P Wang, X Duan, X Tang, ...
Cell stem cell 27 (1), 125-136. e7, 2020
6562020
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Y Han, X Duan, L Yang, BE Nilsson-Payant, P Wang, F Duan, X Tang, ...
Nature 589 (7841), 270-275, 2021
4692021
SARS-CoV-2 infection induces beta cell transdifferentiation
X Tang, S Uhl, T Zhang, D Xue, B Li, JJ Vandana, JA Acklin, ...
Cell metabolism 33 (8), 1577-1591. e7, 2021
1622021
Identification of candidate COVID-19 therapeutics using hPSC-derived lung organoids
Y Han, L Yang, X Duan, F Duan, BE Nilsson-Payant, TM Yaron, P Wang, ...
BioRxiv, 2020
1042020
TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy
C Wang, X Tang, X Sun, Z Miao, Y Lv, Y Yang, H Zhang, P Zhang, Y Liu, ...
Cell research 22 (1), 194-207, 2012
1012012
Injured adult retinal axons with Pten and Socs3 co-deletion reform active synapses with suprachiasmatic neurons
S Li, Q He, H Wang, X Tang, KW Ho, X Gao, Q Zhang, Y Shen, A Cheung, ...
Neurobiology of disease 73, 366-376, 2015
602015
RHCG suppresses tumorigenicity and metastasis in esophageal squamous cell carcinoma via inhibiting NF-κB signaling and MMP1 expression
XY Ming, X Zhang, TT Cao, LY Zhang, JL Qi, NW Kam, XM Tang, YZ Cui, ...
Theranostics 8 (1), 185, 2018
412018
An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection
X Duan, X Tang, MS Nair, T Zhang, Y Qiu, W Zhang, P Wang, Y Huang, ...
Cell reports 37 (6), 2021
392021
Eukaryotic translation initiation factor 5A2 promotes metabolic reprogramming in hepatocellular carcinoma cells
TT Cao, SH Lin, L Fu, Z Tang, CM Che, LY Zhang, XY Ming, TF Liu, ...
Carcinogenesis 38 (1), 94-104, 2017
302017
PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway
Tang, X., Cao, T., Zhu, Y. Zhang, L., Chen, J., Liu, T., Ming, X., Fang, S ...
Cell Death Dis 11 (510), 2020
222020
A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection
X Tang, D Xue, T Zhang, BE Nilsson-Payant, L Carrau, X Duan, ...
Nature Cell Biology 25 (3), 381-389, 2023
82023
A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating
YX Ni, N Zhou, WQ Xue, L Rong, WH Yung, RZ Lin, RYT Kao, ZG Duan, ...
Cell Discovery 4 (1), 65, 2018
62018
Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells
D Xue, N Narisu, DL Taylor, M Zhang, C Grenko, HJ Taylor, T Yan, X Tang, ...
Cell Metabolism 35 (11), 1897-1914. e11, 2023
32023
Single-cell gene expression and chromatin accessibility profiling of human pancreatic islets at basal and stimulatory conditions nominates mechanisms of type 1 diabetes genetic …
RDO Albanus, X Tang, HJ Taylor, N Manickam, M Erdos, N Narisu, Y Han, ...
bioRxiv, 2022.11. 12.516291, 2022
32022
An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals
Z Zhao, RDO Albanus, H Taylor, X Tang, Y Han, P Orchard, A Varshney, ...
Research Square, 2023
12023
Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits
S Hudaiberdiev, DL Taylor, W Song, N Narisu, RM Bhuiyan, HJ Taylor, ...
Proceedings of the National Academy of Sciences 120 (35), e2206612120, 2023
12023
Functional interrogation of twenty type 2 diabetes associated genes using isogenic hESC-derived β-like cells
D Xue, N Narisu, DL Taylor, M Zhang, C Grenko, HJ Taylor, T Yan, X Tang, ...
bioRxiv, 2023.05. 07.539774, 2023
12023
The role of tumor microenvironment in the development, treatment and prognosis of hepatocellular carcinoma
H Wang, H Liu, X Tang, J Chen, Z Ren
Frontiers in Pharmacology 14, 1343175, 2024
2024
283-OR: ADA Presidents' Select Abstract: An Isogenic hPSC-Based Platform for Functional Interrogation of the Role of Multiple T2D-Associated Genes in Pancreatic Beta-Cell Failure
D XUE, N NARISU, T YAN, M ZHANG, C GRENKO, X TANG, J ZHU, ...
Diabetes 72 (Supplement_1), 2023
2023
Role of anterograde motor Kif5b in clathrin-coated vesicle uncoating and clathrin-mediated endocytosis
YX Ni, WQ Xue, N Zhou, WH Yung, RZ Lin, RYT Kao, ZG Duan, XM Tang, ...
bioRxiv, 284166, 2018
2018
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