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Christopher R Shaler
Christopher R Shaler
Sonata Therapeutics
Verified email at sonatatx.com
Title
Cited by
Cited by
Year
Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung
CL Small, CR Shaler, S McCormick, M Jeyanathan, D Damjanovic, ...
The Journal of Immunology 184 (4), 2048-2056, 2010
2562010
MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate …
CR Shaler, J Choi, PT Rudak, A Memarnejadian, PA Szabo, ...
PLoS biology 15 (6), e2001930, 2017
1462017
Within the Enemy’s Camp: contribution of the granuloma to the dissemination, persistence and transmission of Mycobacterium tuberculosis
CR Shaler, CN Horvath, M Jeyanathan, Z Xing
Frontiers in immunology 4, 30, 2013
902013
Mechanisms of delayed anti-tuberculosis protection in the lung of parenteral BCG-vaccinated hosts: a critical role of airway luminal T cells
CN Horvath, CR Shaler, M Jeyanathan, A Zganiacz, Z Xing
Mucosal immunology 5 (4), 420-431, 2012
802012
Understanding delayed T-cell priming, lung recruitment, and airway luminal T-cell responses in host defense against pulmonary tuberculosis
CR Shaler, C Horvath, R Lai, Z Xing
Journal of Immunology Research 2012, 2012
792012
Murine Airway Luminal Antituberculosis Memory CD8 T Cells by Mucosal Immunization Are Maintained Via Antigen-Driven In Situ Proliferation, Independent of …
M Jeyanathan, J Mu, S McCormick, D Damjanovic, CL Small, CR Shaler, ...
American journal of respiratory and critical care medicine 181 (8), 862-872, 2010
772010
Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway
VC Anipindi, P Bagri, K Roth, SE Dizzell, PV Nguyen, CR Shaler, DK Chu, ...
PLoS pathogens 12 (5), e1005589, 2016
692016
PD-1 blockade promotes epitope spreading in anticancer CD8+ T cell responses by preventing fratricidal death of subdominant clones to relieve immunodomination
A Memarnejadian, CE Meilleur, CR Shaler, K Khazaie, JR Bennink, ...
The Journal of Immunology 199 (9), 3348-3359, 2017
682017
Mucosa-associated invariant T cells infiltrate hepatic metastases in patients with colorectal carcinoma but are rendered dysfunctional within and adjacent to tumor microenvironment
CR Shaler, ME Tun-Abraham, AI Skaro, K Khazaie, AJ Corbett, T Mele, ...
Cancer Immunology, Immunotherapy 66, 1563-1575, 2017
672017
Continuous and discontinuous cigarette smoke exposure differentially affects protective Th1 immunity against pulmonary tuberculosis
CR Shaler, CN Horvath, S McCormick, M Jeyanathan, A Khera, ...
PLoS One 8 (3), e59185, 2013
672013
Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe?
SMM Haeryfar, CR Shaler, PT Rudak
Cancer Immunology, Immunotherapy 67 (12), 1885-1896, 2018
582018
Respiratory mucosal immunization with adenovirus gene transfer vector induces helper CD4 T cell‐independent protective immunity
J Mu, M Jeyanathan, CR Shaler, C Horvath, D Damjanovic, A Zganiacz, ...
The journal of gene medicine 12 (8), 693-704, 2010
552010
Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity
M Jeyanathan, D Damjanovic, CR Shaler, R Lai, M Wortzman, C Yin, ...
Mucosal immunology 6 (3), 612-625, 2013
512013
Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells
M Jeyanathan, S McCormick, R Lai, S Afkhami, CR Shaler, CN Horvath, ...
Mucosal immunology 7 (3), 670-683, 2014
422014
Mucosal-associated invariant T cells in chronic inflammatory liver disease
FJ Bolte, B Rehermann
Seminars in liver disease 38 (01), 060-065, 2018
372018
CD1d-and MR1-restricted T cells in sepsis
PA Szabo, RV Anantha, CR Shaler, JK McCormick, SMM Haeryfar
Frontiers in Immunology 6, 401, 2015
372015
The unique lifestyle of Crohn's disease-associated adherent-invasive Escherichia coli
CR Shaler, W Elhenawy, BK Coombes
Journal of molecular biology 431 (16), 2970-2981, 2019
342019
Pulmonary mycobacterial granuloma: increased IL-10 production contributes to establishing a symbiotic host–microbe microenvironment
CR Shaler, K Kugathasan, S McCormick, D Damjanovic, C Horvath, ...
The American journal of pathology 178 (4), 1622-1634, 2011
312011
Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts
CR Shaler, AA Parco, W Elhenawy, J Dourka, J Jury, EF Verdu, ...
Nature Communications 12 (1), 6664, 2021
282021
Therapeutic control of leishmaniasis by inhibitors of the mammalian target of rapamycin
F Khadir, CR Shaler, A Oryan, PT Rudak, DM Mazzuca, T Taheri, ...
PLoS Neglected Tropical Diseases 12 (8), e0006701, 2018
282018
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