| TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer L Caja, F Dituri, S Mancarella, D Caballero-Diaz, A Moustakas, ... International journal of molecular sciences 19 (5), 1294, 2018 | 306 | 2018 |
| Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity I Carmona-Cuenca, C Roncero, P Sancho, L Caja, N Fausto, ... Journal of hepatology 49 (6), 965-976, 2008 | 259 | 2008 |
| Transforming growth factor β as regulator of cancer stemness and metastasis C Bellomo, L Caja, A Moustakas British journal of cancer 115 (7), 761, 2016 | 237 | 2016 |
| The transforming growth factor‐beta (TGF‐β) mediates acquisition of a mesenchymal stem cell‐like phenotype in human liver cells L Caja, E Bertran, J Campbell, N Fausto, I Fabregat Journal of cellular physiology 226 (5), 1214-1223, 2011 | 152 | 2011 |
| Vascular Smooth Muscle Cell Phenotypic Changes in Patients With Marfan Syndrome E Crosas-Molist, T Meirelles, J López-Luque, C Serra-Peinado, J Selva, ... Arteriosclerosis, thrombosis, and vascular biology 35 (4), 960-972, 2015 | 150 | 2015 |
| Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-β–induced cell death through impairing up-regulation of the NADPH oxidase NOX4 L Caja, P Sancho, E Bertran, D Iglesias-Serret, J Gil, I Fabregat Cancer research 69 (19), 7595-7602, 2009 | 140 | 2009 |
| Overactivation of the TGF‐β pathway confers a mesenchymal‐like phenotype and CXCR4‐dependent migratory properties to liver tumor cells E Bertran, E Crosas‐Molist, P Sancho, L Caja, J Lopez‐Luque, E Navarro, ... Hepatology 58 (6), 2032-2044, 2013 | 137 | 2013 |
| Regulation of transcription factor Twist expression by the DNA architectural protein high mobility group A2 during epithelial-to-mesenchymal transition EJ Tan, S Thuault, L Caja, T Carletti, CH Heldin, A Moustakas Journal of Biological Chemistry 287 (10), 7134-7145, 2012 | 131 | 2012 |
| The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-β-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in … P Sancho, E Bertran, L Caja, I Carmona-Cuenca, MM Murillo, I Fabregat Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (2), 253-263, 2009 | 98 | 2009 |
| Differential intracellular signalling induced by TGF-β in rat adult hepatocytes and hepatoma cells: implications in liver carcinogenesis L Caja, C Ortiz, E Bertran, MM Murillo, MJ Miró-Obradors, E Palacios, ... Cellular signalling 19 (4), 683-694, 2007 | 98 | 2007 |
| Role of CXCR4/SDF-1α in the migratory phenotype of hepatoma cells that have undergone epithelial–mesenchymal transition in response to the transforming growth factor-β E Bertran, L Caja, E Navarro, P Sancho, J Mainez, MM Murillo, A Vinyals, ... Cellular signalling 21 (11), 1595-1606, 2009 | 92 | 2009 |
| Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli J Fernando, P Sancho, CM Fernández‐Rodriguez, JL Lledó, L Caja, ... Journal of cellular physiology 227 (4), 1319-1325, 2012 | 89 | 2012 |
| Snail depletes the tumorigenic potential of glioblastoma K Savary, D Caglayan, L Caja, K Tzavlaki, SB Nayeem, T Bergström, ... Oncogene 32 (47), 5409-5420, 2013 | 85 | 2013 |
| Dissecting the effect of targeting the epidermal growth factor receptor on TGF-β-induced-apoptosis in human hepatocellular carcinoma cells L Caja, P Sancho, E Bertran, I Fabregat Journal of hepatology 55 (2), 351-358, 2011 | 65 | 2011 |
| Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells L Caja, K Tzavlaki, MS Dadras, EJ Tan, G Hatem, NP Maturi, A Morén, ... Oncogene 37 (19), 2515, 2018 | 55 | 2018 |
| Transforming growth factor β and bone morphogenetic protein actions in brain tumors L Caja, C Bellomo, A Moustakas FEBS letters 589 (14), 1588-1597, 2015 | 51 | 2015 |
| Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17 J Moreno-Càceres, L Caja, J Mainez, R Mayoral, P Martin-Sanz, ... Cell death & disease 5 (7), e1326, 2014 | 50 | 2014 |
| A Trifluorinated Thiazoline Scaffold Leading to Pro‐apoptotic Agents Targeting Prohibitins A Pérez‐Perarnau, S Preciado, CM Palmeri, C Moncunill‐Massaguer, ... Angewandte Chemie International Edition 53 (38), 10150-10154, 2014 | 48 | 2014 |
| The Epstein–Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins G Coppotelli, N Mughal, S Callegari, R Sompallae, L Caja, ... Nucleic acids research 41 (5), 2950-2962, 2013 | 48 | 2013 |
| Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: role of reactive oxygen species production and … C Ortiz, L Caja, P Sancho, E Bertran, I Fabregat Biochemical pharmacology 75 (10), 1935-1945, 2008 | 44 | 2008 |
