| Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ... Science Translational Medicine 9 (392), eaal3447, 2017 | 192 | 2017 |
| Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4 P Zhao, TM Lieu, N Barlow, M Metcalf, NA Veldhuis, DD Jensen, M Kocan, ... Journal of Biological Chemistry 289 (39), 27215-27234, 2014 | 182 | 2014 |
| Neutrophil elastase activates protease-activated receptor-2 (PAR2) and transient receptor potential vanilloid 4 (TRPV4) to cause inflammation and pain P Zhao, TM Lieu, N Barlow, S Sostegni, S Haerteis, C Korbmacher, ... Journal of Biological Chemistry 290 (22), 13875-13887, 2015 | 166 | 2015 |
| Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution KD Brewer, T Bacaj, A Cavalli, C Camilloni, JD Swarbrick, J Liu, A Zhou, ... Nature structural & molecular biology 22 (7), 555-564, 2015 | 149 | 2015 |
| DOTA-amide lanthanide tag for reliable generation of pseudocontact shifts in protein NMR spectra B Graham, CT Loh, JD Swarbrick, P Ung, J Shin, H Yagi, X Jia, S Chhabra, ... Bioconjugate chemistry 22 (10), 2118-2125, 2011 | 135 | 2011 |
| Lanthanide tags for site-specific ligation to an unnatural amino acid and generation of pseudocontact shifts in proteins CT Loh, K Ozawa, KL Tuck, N Barlow, T Huber, G Otting, B Graham Bioconjugate chemistry 24 (2), 260-268, 2013 | 104 | 2013 |
| Enhanced cytotoxicity through conjugation of a “clickable” luminescent Re (I) complex to a cell-penetrating lipopeptide A Leonidova, V Pierroz, LA Adams, N Barlow, S Ferrari, B Graham, ... ACS medicinal chemistry letters 5 (7), 809-814, 2014 | 80 | 2014 |
| 8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase ML Dennis, MD Lee, JR Harjani, M Ahmed, AJ DeBono, NP Pitcher, ... Chemistry–A European Journal 24 (8), 1922-1930, 2018 | 42 | 2018 |
| Fluorescent diphenylphosphonate-based probes for detection of serine protease activity during inflammation LE Edgington-Mitchell, N Barlow, L Aurelio, A Samha, M Szabo, ... Bioorganic & medicinal chemistry letters 27 (2), 254-260, 2017 | 35 | 2017 |
| Improving membrane permeation in the beyond rule-of-five space by using prodrugs to mask hydrogen bond donors N Barlow, DK Chalmers, BJ Williams-Noonan, PE Thompson, RS Norton ACS Chemical Biology 15 (8), 2070-2078, 2020 | 34 | 2020 |
| Facile, divergent route to bis-Zn (II) dipicolylamine type chemosensors for pyrophosphate LG Pathberiya, N Barlow, T Nguyen, B Graham, KL Tuck Tetrahedron 68 (46), 9435-9439, 2012 | 26 | 2012 |
| Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease‐activated receptor‐2 T Lieu, E Savage, P Zhao, L Edgington‐Mitchell, N Barlow, R Bron, ... British journal of pharmacology 173 (18), 2752-2765, 2016 | 23 | 2016 |
| Exploring the chemical space around 8-mercaptoguanine as a route to new inhibitors of the folate biosynthesis enzyme HPPK S Chhabra, N Barlow, O Dolezal, MK Hattarki, J Newman, TS Peat, ... PloS one 8 (4), e59535, 2013 | 23 | 2013 |
| Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7, 8-dihydropterin … ML Dennis, S Chhabra, ZC Wang, A Debono, O Dolezal, J Newman, ... Journal of Medicinal Chemistry 57 (22), 9612-9626, 2014 | 19 | 2014 |
| A cyclic peptide inhibitor of the iNOS–SPSB protein–protein interaction as a potential anti-infective agent MM Sadek, N Barlow, EWW Leung, BJ Williams-Noonan, BK Yap, ... ACS chemical biology 13 (10), 2930-2938, 2018 | 18 | 2018 |
| Characterisation of a novel coumarin-based fluorescent probe for monitoring nitric oxide production in macrophages RSN Maiada M Sadek, Mina Barzegar Amiri Olia, Cameron J Nowell, Νicholas ... Bioorganic & Medicinal Chemistry 25 (20), 5743-5748, 2017 | 14 | 2017 |
| Granzyme K initiates IL-6 and IL-8 release from epithelial cells by activating protease-activated receptor 2 D Kaiserman, P Zhao, CL Rowe, A Leong, N Barlow, LT Joeckel, ... PloS one 17 (7), e0270584, 2022 | 13 | 2022 |
| Neutrophil elastase activates PAR2 and TRPV4 to cause inflammation and pain P Zhao, T Lieu, N Barlow, S Sostegni, S Haerteis, C Korbmacher, ... J Biol Chem 290, 13875-13887, 2015 | 13 | 2015 |
| IRAP inhibitors: M1-aminopeptidase family inspiration N Barlow, PE Thompson Frontiers in Pharmacology 11, 585930, 2020 | 11 | 2020 |
| Macrocyclic peptidomimetics as inhibitors of insulin-regulated aminopeptidase (IRAP) N Barlow, SR Vanga, J Sävmarker, A Sandström, P Burns, A Hallberg, ... RSC Medicinal Chemistry 11 (2), 234-244, 2020 | 10 | 2020 |
zhao peishenresearch fellow, Monash UniversityVerified email at monash.edu
