The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability C González-Aguilera, C Tous, B Gómez-González, P Huertas, R Luna, ... Molecular biology of the cell 19 (10), 4310-4318, 2008 | 177 | 2008 |
The Rad50 coiled-coil domain is indispensable for Mre11 complex functions M Hohl, Y Kwon, SM Galván, X Xue, C Tous, A Aguilera, P Sung, ... Nature structural & molecular biology 18 (10), 1124-1131, 2011 | 111 | 2011 |
Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair H Gaillard, C Tous, J Botet, C González-Aguilera, MJ Quintero, ... PLoS genetics 5 (2), e1000364, 2009 | 106 | 2009 |
Impairment of transcription elongation by R-loops in vitro C Tous, A Aguilera Biochemical and biophysical research communications 360 (2), 428-432, 2007 | 105 | 2007 |
Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor A Pena, K Gewartowski, S Mroczek, J Cuellar, A Szykowska, A Prokop, ... The EMBO journal 31 (6), 1605-1616, 2012 | 97 | 2012 |
Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange S Muñoz-Galván, C Tous, MG Blanco, EK Schwartz, KT Ehmsen, SC West, ... Molecular and cellular biology, 2012 | 76 | 2012 |
A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors C Tous, AG Rondón, M García‐Rubio, C González‐Aguilera, R Luna, ... The EMBO Journal 30 (10), 1953-1964, 2011 | 61 | 2011 |
Gemcitabine plus sirolimus for relapsed and progressing osteosarcoma patients after standard chemotherapy: a multicenter, single-arm phase II trial of Spanish Group for … J Martin-Broto, A Redondo, C Valverde, MA Vaz, J Mora, XG Del Muro, ... Annals of Oncology 28 (12), 2994-2999, 2017 | 59 | 2017 |
Interdependence of the rad50 hook and globular domain functions M Hohl, T Kochańczyk, C Tous, A Aguilera, A Krężel, JHJ Petrini Molecular cell 57 (3), 479-491, 2015 | 54 | 2015 |
Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity M García-Rubio, S Chávez, P Huertas, C Tous, S Jimeno, R Luna, ... Molecular Genetics and Genomics 279, 123-132, 2008 | 47 | 2008 |
Nab2 functions in the metabolism of RNA driven by polymerases II and III C González-Aguilera, C Tous, R Babiano, J de la Cruz, R Luna, ... Molecular biology of the cell 22 (15), 2729-2740, 2011 | 46 | 2011 |
Conditional Expression of RNase P in the CyanobacteriumSynechocystis sp. PCC6803 Allows Detection of Precursor RNAs: INSIGHT IN THE IN VIVO MATURATION PATHWAY OF TRANSFER AND … C Tous, MA Vega-Palas, A Vioque Journal Of Biological Chemistry 276 (31), 29059-29066, 2001 | 44 | 2001 |
Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication F Cortes-Ledesma, C Tous, A Aguilera Nucleic acids research 35 (19), 6560-6570, 2007 | 40 | 2007 |
Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1) M Perez, J Peinado-Serrano, JM Garcia-Heredia, I Felipe-Abrio, C Tous, ... Oncotarget 7 (41), 67033, 2016 | 24 | 2016 |
New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation S Jimeno, C Tous, ML García-Rubio, M Ranes, C González-Aguilera, ... Molecular and Cellular Biology 31 (4), 674-685, 2011 | 18 | 2011 |
Control of the function of the transcription and repair factor TFIIH by the action of the cochaperone Ydj1 M Moriel-Carretero, C Tous, A Aguilera Proceedings of the National Academy of Sciences 108 (37), 15300-15305, 2011 | 13 | 2011 |
Mutation in ROBO3 Gene in Patients with Horizontal Gaze Palsy with Progressive Scoliosis Syndrome: A Systematic Review E Pinero-Pinto, V Pérez-Cabezas, C Tous-Rivera, JM Sánchez-González, ... International journal of environmental research and public health 17 (12), 4467, 2020 | 12 | 2020 |
Comparison of two types of surgical gastrostomies, open and laparoscopic in home enteral nutrition C Tous, J Parejo Campos, R Oliva Rodríguez, P Serrano Aguayo, ... Aula Médica Ediciones, 2012 | 9 | 2012 |
Small molecule-inducible gene regulatory systems in mammalian cells: progress and design principles M Siddiqui, C Tous, WW Wong Current opinion in biotechnology 78, 102823, 2022 | 7 | 2022 |
Phase II trial of gemcitabine plus rapamycin as second line in advanced osteosarcoma: A Spanish Group for Sarcoma Research (GEIS) Study. J Martin Broto, A Redondo, CM Valverde, MÁ Vaz Salgado, J Mora, ... Journal of Clinical Oncology 33 (15_suppl), 10530-10530, 2015 | 3 | 2015 |