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Ming-Ru Wu
Ming-Ru Wu
Dana-Farber Cancer Institute and Harvard Medical School
Verified email at dfci.harvard.edu - Homepage
Title
Cited by
Cited by
Year
NKG2D ligands as therapeutic targets
P Spear, MR Wu, ML Sentman, CL Sentman
Cancer immunity 13 (2), 8, 2013
3132013
An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo
T Zhang, MR Wu, CL Sentman
The Journal of Immunology 189 (5), 2290-2299, 2012
1412012
Synthetic RNA-based immunomodulatory gene circuits for cancer immunotherapy
L Nissim, MR Wu, E Pery, A Binder-Nissim, HI Suzuki, D Stupp, ...
Cell 171 (5), 1138-1150. e15, 2017
1402017
Engineering advanced cancer therapies with synthetic biology
MR Wu, B Jusiak, TK Lu
Nature Reviews Cancer 19 (4), 187-195, 2019
912019
Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade
H Lee, C Yuan, A Hammet, A Mahajan, ESW Chen, MR Wu, MI Su, ...
Molecular cell 30 (6), 767-778, 2008
892008
Experimentally-derived fibroblast gene signatures identify molecular pathways associated with distinct subsets of systemic sclerosis patients in three independent cohorts
ME Johnson, JM Mahoney, J Taroni, JL Sargent, E Marmarelis, MR Wu, ...
PloS one 10 (1), e0114017, 2015
842015
B7H6-specific bispecific T cell engagers lead to tumor elimination and host antitumor immunity
MR Wu, T Zhang, AT Gacerez, TA Coupet, LR DeMars, CL Sentman
The Journal of Immunology 194 (11), 5305-5311, 2015
712015
B7H6-specific chimeric antigen receptors lead to tumor elimination and host antitumor immunity
MR Wu, T Zhang, LR DeMars, CL Sentman
Gene therapy 22 (8), 675-684, 2015
692015
Mechanisms of acute toxicity in NKG2D chimeric antigen receptor T cell–treated mice
ML Sentman, JM Murad, WJ Cook, MR Wu, J Reder, SH Baumeister, ...
The Journal of Immunology 197 (12), 4674-4685, 2016
682016
A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS)
MR Wu, L Nissim, D Stupp, E Pery, A Binder-Nissim, K Weisinger, ...
Nature communications 10 (1), 2880, 2019
552019
DNAM-1-based chimeric antigen receptors enhance T cell effector function and exhibit in vivo efficacy against melanoma
MR Wu, T Zhang, A Alcon, CL Sentman
Cancer Immunology, Immunotherapy 64, 409-418, 2015
492015
Versatile and on-demand biologics co-production in yeast
J Cao, P Perez-Pinera, K Lowenhaupt, MR Wu, O Purcell, ...
Nature communications 9 (1), 77, 2018
332018
A synthetic transcription platform for programmable gene expression in mammalian cells
WCW Chen, L Gaidukov, Y Lai, MR Wu, J Cao, MJ Gutbrod, GCG Choi, ...
Nature Communications 13 (1), 6167, 2022
122022
Contact guidance and collective migration in the advancing epithelial monolayer
G Lee, L Atia, B Lan, Y Sharma, L Nissim, MR Wu, E Pery, TK Lu, CY Park, ...
Connective tissue research 59 (4), 309-315, 2018
102018
Targeting multiple types of tumors using NKG2D-coated iron oxide nanoparticles
MR Wu, WJ Cook, T Zhang, CL Sentman
Nanotechnology 25 (47), 475101, 2014
52014
Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
J Suh, H Kim, J Min, HJ Yeon, M Hemberg, L Scimeca, MR Wu, HG Kang, ...
Cell Reports Medicine 5 (1), 2024
22024
Tumor immunotherapy
TKT Lu, L Nissim, MR Wu
US Patent App. 15/737,829, 2019
22019
Harnessing natural killer cell receptors for tumor immunotherapy
MR Wu
Dartmouth College, 2015
12015
Synthetic biology approaches for improving the specificity and efficacy of cancer immunotherapy
B Zhu, H Yin, D Zhang, M Zhang, X Chao, L Scimeca, MR Wu
Cellular & Molecular Immunology, 1-12, 2024
2024
Synthetic promoters
TKT Lu, L Nissim, MR Wu
US Patent 11,718,860, 2023
2023
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Articles 1–20