| Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma AG Uren, K O'Rourke, L Aravind, MT Pisabarro, S Seshagiri, EV Koonin, ... Molecular cell 6 (4), 961-967, 2000 | 1317 | 2000 |
| Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype AG Uren, L Wong, M Pakusch, KJ Fowler, FJ Burrows, DL Vaux, ... Current Biology 10 (21), 1319-1328, 2000 | 728 | 2000 |
| Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors AG Uren, M Pakusch, CJ Hawkins, KL Puls, DL Vaux Proceedings of the National Academy of Sciences 93 (10), 4974-4978, 1996 | 674 | 1996 |
| Retroviral insertional mutagenesis: past, present and future AG Uren, J Kool, A Berns, M Van Lohuizen Oncogene 24 (52), 7656-7672, 2005 | 335 | 2005 |
| The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone EK Speliotes, A Uren, D Vaux, HR Horvitz Molecular cell 6 (2), 211-223, 2000 | 320 | 2000 |
| Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts AG Uren, EJ Coulson, DL Vaux Trends in biochemical sciences 23 (5), 159-162, 1998 | 280 | 1998 |
| Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice GS Vassiliou, JL Cooper, R Rad, J Li, S Rice, A Uren, L Rad, P Ellis, ... Nature genetics 43 (5), 470-475, 2011 | 260 | 2011 |
| Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division AG Uren, T Beilharz, MJ O’Connell, SJ Bugg, R Van Driel, DL Vaux, ... Proceedings of the National Academy of Sciences 96 (18), 10170-10175, 1999 | 260 | 1999 |
| Cardiac glycosides are broad-spectrum senolytics A Guerrero, N Herranz, B Sun, V Wagner, S Gallage, R Guiho, K Wolter, ... Nature metabolism 1 (11), 1074-1088, 2019 | 248 | 2019 |
| Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis HN March, AG Rust, NA Wright, J ten Hoeve, J de Ridder, M Eldridge, ... Nature genetics 43 (12), 1202-1209, 2011 | 209 | 2011 |
| Large-scale mutagenesis in p19ARF-and p53-deficient mice identifies cancer genes and their collaborative networks AG Uren, J Kool, K Matentzoglu, J de Ridder, J Mattison, M van Uitert, ... Cell 133 (4), 727-741, 2008 | 207 | 2008 |
| A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites AG Uren, H Mikkers, J Kool, L van der Weyden, AH Lund, CH Wilson, ... Nature protocols 4 (5), 789-798, 2009 | 197 | 2009 |
| Inhibition of interleukin 1β-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP CJ Hawkins, AG Uren, G Häcker, RL Medcalf, DL Vaux Proceedings of the National Academy of Sciences 93 (24), 13786-13790, 1996 | 156 | 1996 |
| Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens J De Ridder, A Uren, J Kool, M Reinders, L Wessels PLoS computational biology 2 (12), e166, 2006 | 143 | 2006 |
| Molecular and clinical aspects of apoptosis AG Uren, DL Vaux Pharmacology & therapeutics 72 (1), 37-50, 1996 | 112 | 1996 |
| Galactose‐modified duocarmycin prodrugs as senolytics A Guerrero, R Guiho, N Herranz, A Uren, DJ Withers, ... Aging Cell 19 (4), e13133, 2020 | 106 | 2020 |
| TRAF proteins and meprins share a conserved domain. AG Uren, DL Vaux Trends in biochemical sciences 21 (7), 244, 1996 | 79 | 1996 |
| Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells E Curry, I Green, N Chapman-Rothe, E Shamsaei, S Kandil, FL Cherblanc, ... Clinical epigenetics 7 (1), 1, 2015 | 72 | 2015 |
| Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells CJ Hawkins, PG Ekert, AG Uren, SP Holmgreen, DL Vaux Cell Death & Differentiation 5 (7), 569-576, 1998 | 59 | 1998 |
| Visualizing changes in Cdkn1c expression links early-life adversity to imprint mis-regulation in adults M Van de Pette, A Abbas, A Feytout, G McNamara, L Bruno, WK To, ... Cell reports 18 (5), 1090-1099, 2017 | 48 | 2017 |
David L VauxDeputy Director, The Walter and Eliza Hall InstituteVerified email at wehi.edu.au
