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Athri D Rathnayake
Athri D Rathnayake
Verified email at northwestern.edu
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Cited by
Year
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice
AD Rathnayake, J Zheng, Y Kim, KD Perera, S Mackin, DK Meyerholz, ...
Science translational medicine 12 (557), eabc5332, 2020
2262020
Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element
ACG Kankanamalage, Y Kim, VC Damalanka, AD Rathnayake, AR Fehr, ...
European journal of medicinal chemistry 150, 334-346, 2018
1142018
Antiviral drug discovery: norovirus proteases and development of inhibitors
KO Chang, Y Kim, S Lovell, AD Rathnayake, WC Groutas
Viruses 11 (2), 197, 2019
812019
Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease
CS Dampalla, Y Kim, N Bickmeier, AD Rathnayake, HN Nguyen, J Zheng, ...
Journal of Medicinal Chemistry, 2021
482021
Protease inhibitors broadly effective against feline, ferret and mink coronaviruses
KD Perera, ACG Kankanamalage, AD Rathnayake, A Honeyfield, ...
Antiviral Research 160, 79-86, 2018
422018
Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor
KD Perera, AD Rathnayake, H Liu, NC Pedersen, WC Groutas, KO Chang, ...
Veterinary microbiology 237, 108398, 2019
352019
Structure-guided design of potent inhibitors of SARS-CoV-2 3CL protease: structural, biochemical, and cell-based studies
CS Dampalla, AD Rathnayake, KD Perera, ARM Jesri, HN Nguyen, ...
Journal of medicinal chemistry 64 (24), 17846-17865, 2021
322021
Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors
ACG Kankanamalage, Y Kim, AD Rathnayake, VC Damalanka, ...
European journal of medicinal chemistry 126, 502-516, 2017
262017
Structure-guided design of potent spirocyclic inhibitors of severe acute respiratory syndrome coronavirus-2 3C-like protease
CS Dampalla, AD Rathnayake, AC Galasiti Kankanamalage, Y Kim, ...
Journal of Medicinal Chemistry 65 (11), 7818-7832, 2022
232022
Design, synthesis, and evaluation of novel prodrugs of transition state inhibitors of norovirus 3CL protease
AC Galasiti Kankanamalage, Y Kim, AD Rathnayake, KR Alliston, ...
Journal of Medicinal Chemistry 60 (14), 6239-6248, 2017
222017
New measurements of the beam-normal single spin asymmetry in elastic electron scattering over a range of spin-0 nuclei
D Adhikari, H Albataineh, D Androic, K Aniol, DS Armstrong, T Averett, ...
Physical review letters 128 (14), 142501, 2022
212022
Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease
VC Damalanka, Y Kim, ACG Kankanamalage, AD Rathnayake, ...
European journal of medicinal chemistry 143, 881-890, 2018
162018
Organic Reaction Mechanisms, Selected Problems, and Solutions
WC Groutas, AD Rathnayake
CRC Press, 2023
152023
Structure-guided optimization of dipeptidyl inhibitors of norovirus 3CL protease
AD Rathnayake, Y Kim, CS Dampalla, HN Nguyen, ARM Jesri, ...
Journal of Medicinal Chemistry 63 (20), 11945-11963, 2020
152020
Putative structural rearrangements associated with the interaction of macrocyclic inhibitors with norovirus 3CL protease
AC Galasiti Kankanamalage, PM Weerawarna, AD Rathnayake, Y Kim, ...
Proteins: Structure, Function, and Bioinformatics 87 (7), 579-587, 2019
122019
Broad-spectrum cyclopropane-based inhibitors of coronavirus 3C-like proteases: biochemical, structural, and virological studies
CS Dampalla, HN Nguyen, AD Rathnayake, Y Kim, KD Perera, ...
ACS Pharmacology & Translational Science 6 (1), 181-194, 2022
92022
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med 12: eabc5332
AD Rathnayake, J Zheng, Y Kim, KD Perera, S Mackin, DK Meyerholz, ...
72020
Determination of in-vitro Equivalence of Paracetamol Tablets
AD Rathnayake, U Mannapperuma, D Thambawita, KPB Herath, ...
International Journal of Multidisciplinary Studies 1 (1), 75-83, 2016
62016
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med. 2020; 12 (557)
AD Rathnayake, J Zheng, Y Kim, KD Perera, S Mackin, DK Meyerholz, ...
Epub 2020/08/05. doi: 10.1126/scitranslmed. abc5332. PubMed PMID: 32747425, 0
6
A Direct Detection Search for Hidden Sector New Particles in the 3-60 MeV Mass Range
A Ahmidouch, S Davis, A Gasparian, TJ Hague, S Mtingwa, R Pedroni, ...
arXiv preprint arXiv:2108.13276, 2021
52021
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