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Sarah J Piper
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Structure and dynamics of the CGRP receptor in apo and peptide-bound forms
TM Josephs, MJ Belousoff, YL Liang, SJ Piper, J Cao, DJ Garama, ...
Science 372 (6538), eabf7258, 2021
622021
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity
JI Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ...
PLoS biology 19 (6), e3001295, 2021
492021
Structure and dynamics of the active Gs-coupled human secretin receptor
M Dong, G Deganutti, SJ Piper, YL Liang, M Khoshouei, MJ Belousoff, ...
Nature communications 11 (1), 4137, 2020
492020
Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
SJ Piper, L Brillault, R Rothnagel, TI Croll, JK Box, I Chassagnon, ...
Nature communications 10 (1), 1952, 2019
362019
Structural and functional diversity among agonist-bound states of the GLP-1 receptor
BP Cary, G Deganutti, P Zhao, TT Truong, SJ Piper, X Liu, MJ Belousoff, ...
Nature chemical biology 18 (3), 256-263, 2022
282022
Membranes under the Magnetic Lens: A Dive into the Diverse World of Membrane Protein Structures Using Cryo-EM
SJ Piper, RM Johnson, D Wootten, PM Sexton
Chemical Reviews 122 (17), 13989-14017, 2022
222022
Targeting VIP and PACAP Receptor Signaling: New Insights into Designing Drugs for the PACAP Subfamily of Receptors
J Lu, SJ Piper, P Zhao, LJ Miller, D Wootten, PM Sexton
International Journal of Molecular Sciences 23 (15), 8069, 2022
172022
Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor
RM Johnson, X Zhang, SJ Piper, TJ Nettleton, TH Vandekolk, ...
Biochemical and Biophysical Research Communications 578, 84-90, 2021
152021
New insights into the structure and function of class B1 GPCRs
BP Cary, X Zhang, J Cao, RM Johnson, SJ Piper, EJ Gerrard, D Wootten, ...
Endocrine Reviews 44 (3), 492-517, 2023
142023
Molecular insights into peptide agonist engagement with the PTH receptor
BP Cary, EJ Gerrard, MJ Belousoff, MM Fletcher, Y Jiang, IC Russell, ...
Structure 31 (6), 668-676. e5, 2023
62023
A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid
L Perlaza-Jiménez, KS Tan, SJ Piper, RM Johnson, RS Bamert, ...
Microbiology spectrum 10 (4), e00583-22, 2022
42022
Understanding VPAC receptor family peptide binding and selectivity
SJ Piper, G Deganutti, J Lu, P Zhao, YL Liang, Y Lu, MM Fletcher, ...
Nature Communications 13 (1), 7013, 2022
32022
ABC toxins: Self-assembling nanomachines for the targeted cellular delivery of bioactive proteins
IR Chassagnon, SJ Piper, MJ Landsberg
Comprehensive Nanoscience and Nanotechnology, 279-298, 2019
12019
Secretin amino-terminal structure-activity relationships and complementary mutagenesis at the site of docking to the secretin receptor
JE Milburn, KG Harikumar, SJ Piper, S Raval, A Christopoulos, D Wootten, ...
Molecular Pharmacology 101 (6), 400-407, 2022
2022
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins: insight into mechanisms of G protein selectivity
J Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ...
bioRxiv, 2021
2021
Structural studies of the Yersinia entomophaga ABC toxin complex YenTc using cryo-EM
SJ Piper
2019
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Articles 1–16