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Henry Paulson
Henry Paulson
Verified email at umich.edu - Homepage
Title
Cited by
Cited by
Year
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
21752019
siRNA-mediated gene silencing in vitro and in vivo
H Xia, Q Mao, HL Paulson, BL Davidson
Nature biotechnology 20 (10), 1006-1010, 2002
13552002
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70
JM Warrick, HY Chan, GL Gray-Board, Y Chai, HL Paulson, NM Bonini
Nature genetics 23 (4), 425-428, 1999
10541999
Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3
HL Paulson, MK Perez, Y Trottier, JQ Trojanowski, SH Subramony, ...
Neuron 19 (2), 333-344, 1997
10071997
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
9012017
RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model
SQ Harper, PD Staber, X He, SL Eliason, IH Martins, Q Mao, L Yang, ...
Proceedings of the National Academy of Sciences 102 (16), 5820-5825, 2005
8492005
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
JM Warrick, HL Paulson, GL Gray-Board, QT Bui, KH Fischbeck, ...
Cell 93 (6), 939-949, 1998
8271998
RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia
H Xia, Q Mao, SL Eliason, SQ Harper, IH Martins, HT Orr, HL Paulson, ...
Nature medicine 10 (8), 816-820, 2004
8232004
CREB-binding protein sequestration by expanded polyglutamine
A McCampbell, JP Taylor, AA Taye, J Robitschek, M Li, J Walcott, D Merry, ...
Human molecular genetics 9 (14), 2197-2202, 2000
6812000
Allele-specific silencing of dominant disease genes
VM Miller, H Xia, GL Marrs, CM Gouvion, G Lee, BL Davidson, ...
Proceedings of the National Academy of Sciences 100 (12), 7195-7200, 2003
6182003
Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease
Y Chai, SL Koppenhafer, NM Bonini, HL Paulson
Journal of Neuroscience 19 (23), 10338-10347, 1999
5671999
Spinocerebellar ataxia
T Klockgether, C Mariotti, HL Paulson
Nature reviews Disease primers 5 (1), 24, 2019
5022019
Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro
Y Chai, SL Koppenhafer, SJ Shoesmith, MK Perez, HL Paulson
Human molecular genetics 8 (4), 673-682, 1999
5011999
CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome
PK Todd, SY Oh, A Krans, F He, C Sellier, M Frazer, AJ Renoux, K Chen, ...
Neuron 78 (3), 440-455, 2013
4972013
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model
MM Harraz, JJ Marden, W Zhou, Y Zhang, A Williams, VS Sharov, ...
The Journal of clinical investigation 118 (2), 659-670, 2008
4282008
Trinucleotide repeats in neurogenetic disorders
HL Paulson, KH Fischbeck
Annual review of neuroscience 19 (1), 79-107, 1996
4241996
Polyglutamine neurodegeneration: protein misfolding revisited
AJ Williams, HL Paulson
Trends in neurosciences 31 (10), 521-528, 2008
4122008
Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila
HYE Chan, JM Warrick, GL Gray-Board, HL Paulson, NM Bonini
Human molecular genetics 9 (19), 2811-2820, 2000
4102000
Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation
MK Perez, HL Paulson, SJ Pendse, SJ Saionz, NM Bonini, RN Pittman
The Journal of cell biology 143 (6), 1457-1470, 1998
3841998
Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7
U Rüb, L Schöls, H Paulson, G Auburger, P Kermer, JC Jen, K Seidel, ...
Progress in neurobiology 104, 38-66, 2013
3642013
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