| Circular ecDNA promotes accessible chromatin and high oncogene expression S Wu, KM Turner, N Nguyen, R Raviram, M Erb, J Santini, J Luebeck, ... Nature 575 (7784), 699-703, 2019 | 392 | 2019 |
| Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers H Kim, NP Nguyen, K Turner, S Wu, AD Gujar, J Luebeck, J Liu, ... Nature genetics 52 (9), 891-897, 2020 | 298 | 2020 |
| Altered cellular metabolism in gliomas—An emerging landscape of actionable co-dependency targets J Bi, S Chowdhry, S Wu, W Zhang, K Masui, PS Mischel Nature Reviews Cancer 20 (1), 57-70, 2020 | 224 | 2020 |
| Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells M Shu, X Zheng, S Wu, H Lu, T Leng, W Zhu, Y Zhou, Y Ou, X Lin, Y Lin, ... Molecular cancer 10, 1-17, 2011 | 149 | 2011 |
| Oncogene amplification in growth factor signaling pathways renders cancers dependent on membrane lipid remodeling J Bi, TA Ichu, C Zanca, H Yang, W Zhang, Y Gu, S Chowdhry, A Reed, ... Cell metabolism 30 (3), 525-538. e8, 2019 | 148 | 2019 |
| ecDNA hubs drive cooperative intermolecular oncogene expression KL Hung, KE Yost, L Xie, Q Shi, K Helmsauer, J Luebeck, R Schöpflin, ... Nature 600 (7890), 731-736, 2021 | 147 | 2021 |
| Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers Y Lin, H Zhang, J Liang, K Li, W Zhu, L Fu, F Wang, X Zheng, H Shi, S Wu, ... Proceedings of the National Academy of Sciences of the United States of America, 2014 | 146 | 2014 |
| The anti-Warburg effect elicited by the cAMP-PGC1α pathway drives differentiation of glioblastoma cells into astrocytes F Xing, Y Luan, J Cai, S Wu, J Mai, J Gu, H Zhang, K Li, Y Lin, X Xiao, ... Cell reports 18 (2), 468-481, 2017 | 102 | 2017 |
| MiR-135a functions as a selective killer of malignant glioma S Wu, Y Lin, D Xu, J Chen, M Shu, Y Zhou, W Zhu, X Su, Y Zhou, P Qiu, ... Oncogene 31 (34), 3866-3874, 2012 | 102 | 2012 |
| Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity C Zanca, GR Villa, JA Benitez, AH Thorne, T Koga, M D'Antonio, ... Genes & development 31 (12), 1212-1227, 2017 | 65 | 2017 |
| MicroRNA 335 is required for differentiation of malignant glioma cells induced by activation of cAMP/protein kinase A pathway M Shu, Y Zhou, W Zhu, H Zhang, S Wu, J Chen, G Yan Molecular pharmacology 81 (3), 292-298, 2012 | 64 | 2012 |
| The evolutionary dynamics of extrachromosomal DNA in human cancers JT Lange, JC Rose, CY Chen, Y Pichugin, L Xie, J Tang, KL Hung, ... Nature genetics 54 (10), 1527-1533, 2022 | 57 | 2022 |
| Extrachromosomal DNA: an emerging hallmark in human cancer S Wu, V Bafna, HY Chang, PS Mischel Annual Review of Pathology: Mechanisms of Disease 17, 367-386, 2022 | 56 | 2022 |
| Triptolide cooperates with Cisplatin to induce apoptosis in gemcitabine-resistant pancreatic cancer W Zhu, J Li, S Wu, S Li, L Le, X Su, P Qiu, H Hu, G Yan Pancreas 41 (7), 1029-1038, 2012 | 56 | 2012 |
| Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance SH Wu, JF Bi, T Cloughesy, WK Cavenee, PS Mischel Cancer Biology & Medicine 11 (4), 255-263, 2014 | 55 | 2014 |
| Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug J Bi, A Khan, J Tang, AM Armando, S Wu, W Zhang, RC Gimple, A Reed, ... Cell reports 37 (5), 2021 | 47 | 2021 |
| Single bout short duration fluid shear stress induces osteogenic differentiation of MC3T3-E1 cells via integrin β1 and BMP2 signaling cross-talk Z Mai, Z Peng, S Wu, J Zhang, L Chen, H Liang, D Bai, G Yan, H Ai PLoS One 8 (4), e61600, 2013 | 46 | 2013 |
| Inhibition of cancer cell proliferation by midazolam by targeting transient receptor potential melastatin 7 Y Dou, Y Li, J Chen, S Wu, X Xiao, S Xie, L Tang, M Yan, Y Wang, J Lin, ... Oncology letters 5 (3), 1010-1016, 2013 | 41 | 2013 |
| Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant … M Shu, Y Zhou, W Zhu, S Wu, X Zheng, G Yan Molecular oncology 5 (3), 265-272, 2011 | 36 | 2011 |
| Targeting cancer's metabolic co-dependencies: A landscape shaped by genotype and tissue context J Bi, S Wu, W Zhang, PS Mischel Biochimica Et Biophysica Acta (BBA)-Reviews on Cancer 1870 (1), 76-87, 2018 | 33 | 2018 |
Paul MischelStanford UniversityVerified email at stanford.edu
