Stem cell fate in cancer growth, progression and therapy resistance NK Lytle, AG Barber, T Reya Nature Reviews Cancer 18 (11), 669-680, 2018 | 536 | 2018 |
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring YU Shi, W Gao, NK Lytle, P Huang, X Yuan, AM Dann, M Ridinger-Saison, ... Nature 569 (7754), 131-135, 2019 | 333 | 2019 |
Wnt signaling in normal and malignant hematopoiesis W Lento, K Congdon, C Voermans, M Kritzik, T Reya Cold Spring Harbor perspectives in biology 5 (2), a008011, 2013 | 173 | 2013 |
Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche HA Himburg, JR Harris, T Ito, P Daher, JL Russell, M Quarmyne, PL Doan, ... Cell reports 2 (4), 964-975, 2012 | 155 | 2012 |
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma RG Fox, NK Lytle, DV Jaquish, FD Park, T Ito, J Bajaj, CS Koechlein, ... Nature 534 (7607), 407-411, 2016 | 140 | 2016 |
A multiscale map of the stem cell state in pancreatic adenocarcinoma NK Lytle, LP Ferguson, N Rajbhandari, K Gilroy, RG Fox, A Deshpande, ... Cell 177 (3), 572-586. e22, 2019 | 132 | 2019 |
Epigenetic and transcriptomic profiling of mammary gland development and tumor models disclose regulators of cell state plasticity C Dravis, CY Chung, NK Lytle, J Herrera-Valdez, G Luna, CL Trejo, ... Cancer cell 34 (3), 466-482. e6, 2018 | 130 | 2018 |
Stress-activated NRF2-MDM2 cascade controls neoplastic progression in pancreas J Todoric, L Antonucci, G Di Caro, N Li, X Wu, NK Lytle, D Dhar, ... Cancer cell 32 (6), 824-839. e8, 2017 | 119 | 2017 |
Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade X Wu, W Zhang, J Font-Burgada, T Palmer, AS Hamil, SK Biswas, ... Proceedings of the National Academy of Sciences 111 (38), 13870-13875, 2014 | 119 | 2014 |
Musashi signaling in stem cells and cancer RG Fox, FD Park, CS Koechlein, M Kritzik, T Reya Annual review of cell and developmental biology 31, 249-267, 2015 | 117 | 2015 |
Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia B Zimdahl, T Ito, A Blevins, J Bajaj, T Konuma, J Weeks, CS Koechlein, ... Nature genetics 46 (3), 245-252, 2014 | 117 | 2014 |
Transcriptional regulation of B-cell differentiation T Reya, G Rudolf Current opinion in immunology 10 (2), 158-165, 1998 | 112 | 1998 |
Inhibition of apoptosome formation by suppression of Hsp90β phosphorylation in tyrosine kinase-induced leukemias M Kurokawa, C Zhao, T Reya, S Kornbluth Molecular and cellular biology 28 (17), 5494-5506, 2008 | 107 | 2008 |
CD98-mediated adhesive signaling enables the establishment and propagation of acute myelogenous leukemia J Bajaj, T Konuma, NK Lytle, HY Kwon, JN Ablack, JM Cantor, D Rizzieri, ... Cancer cell 30 (5), 792-805, 2016 | 106 | 2016 |
Stem cells in cancer initiation and progression J Bajaj, E Diaz, T Reya Journal of Cell Biology 219 (1), e201911053, 2019 | 103 | 2019 |
GLI2 inhibition abrogates human leukemia stem cell dormancy A Sadarangani, G Pineda, KM Lennon, HJ Chun, A Shih, AE Schairer, ... Journal of translational medicine 13, 1-14, 2015 | 101 | 2015 |
Calmodulin-dependent protein kinase IV regulates hematopoietic stem cell maintenance*♦ CM Kitsos, U Sankar, M Illario, JM Colomer-Font, AW Duncan, TJ Ribar, ... Journal of Biological Chemistry 280 (39), 33101-33108, 2005 | 85 | 2005 |
Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration W Lento, T Ito, C Zhao, JR Harris, W Huang, C Jiang, K Owzar, S Piryani, ... Genes & development 28 (9), 995-1004, 2014 | 82 | 2014 |
Tetraspanin 3 is required for the development and propagation of acute myelogenous leukemia HY Kwon, J Bajaj, T Ito, A Blevins, T Konuma, J Weeks, NK Lytle, ... Cell stem cell 17 (2), 152-164, 2015 | 78 | 2015 |
Activation of Wnt signaling in hematopoietic regeneration KL Congdon, C Voermans, EC Ferguson, LN DiMascio, M Uqoezwa, ... Stem cells 26 (5), 1202-1210, 2008 | 76 | 2008 |