| Evolution of a split RNA polymerase as a versatile biosensor platform J Pu, J Zinkus-Boltz, BC Dickinson Nature chemical biology 13 (4), 432-438, 2017 | 125 | 2017 |
| Hijacking a hydroxyethyl unit from a central metabolic ketose into a nonribosomal peptide assembly line C Peng, JY Pu, LQ Song, XH Jian, MC Tang, GL Tang Proceedings of the National Academy of Sciences 109 (22), 8540-8545, 2012 | 41 | 2012 |
| Synthesis of potential anticancer 1-(1H-Indol-3-yl) isoquinolines by silver nitrate mediated tandem reactions of 2-alkynylbenzaldehyde azines and indoles YH Zhao, Y Luo, Y Zhu, H Wang, H Zhou, H Tan, Z Zhou, YC Ma, W Xie, ... Synlett 29 (06), 773-778, 2018 | 40 | 2018 |
| Naphthyridinomycin biosynthesis revealing the use of leader peptide to guide nonribosomal peptide assembly JY Pu, C Peng, MC Tang, Y Zhang, JP Guo, LQ Song, Q Hua, GL Tang Organic letters 15 (14), 3674-3677, 2013 | 39 | 2013 |
| Contingency and chance erase necessity in the experimental evolution of ancestral proteins VC Xie, J Pu, BPH Metzger, JW Thornton, BC Dickinson Elife 10, e67336, 2021 | 38 | 2021 |
| Extracellularly oxidative activation and inactivation of matured prodrug for cryptic self-resistance in naphthyridinomycin biosynthesis Y Zhang, WH Wen, JY Pu, MC Tang, L Zhang, C Peng, Y Xu, GL Tang Proceedings of the National Academy of Sciences 115 (44), 11232-11237, 2018 | 30 | 2018 |
| Evolution of C‐terminal modification tolerance in full‐length and split T7 RNA Polymerase biosensors J Pu, M Disare, BC Dickinson ChemBioChem 20 (12), 1547-1553, 2019 | 25 | 2019 |
| Characterization of AvaR1, an autoregulator receptor that negatively controls avermectins production in a high avermectin-producing strain JB Wang, F Zhang, JY Pu, J Zhao, QF Zhao, GL Tang Biotechnology letters 36, 813-819, 2014 | 25 | 2014 |
| Multidimensional control of Cas9 by evolved RNA polymerase-based biosensors J Pu, K Kentala, BC Dickinson ACS chemical biology 13 (2), 431-437, 2018 | 24 | 2018 |
| A panel of protease-responsive RNA polymerases respond to biochemical signals by production of defined RNA outputs in live cells J Pu, I Chronis, D Ahn, BC Dickinson Journal of the American Chemical Society 137 (51), 15996-15999, 2015 | 24 | 2015 |
| Catalysis of extracellular deamination by a FAD‐linked oxidoreductase after prodrug maturation in the biosynthesis of saframycin A LQ Song, YY Zhang, JY Pu, MC Tang, C Peng, GL Tang Angewandte Chemie 129 (31), 9244-9248, 2017 | 20 | 2017 |
| RNA polymerase tags to monitor multidimensional protein–protein interactions reveal pharmacological engagement of Bcl-2 proteins J Pu, JA Dewey, A Hadji, JL LaBelle, BC Dickinson Journal of the American Chemical Society 139 (34), 11964-11972, 2017 | 19 | 2017 |
| Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics WH Wen, Y Zhang, YY Zhang, Q Yu, CC Jiang, MC Tang, JY Pu, L Wu, ... Nature Communications 12 (1), 7085, 2021 | 12 | 2021 |
| In vivo investigation of the role of SfmO2 in saframycin A biosynthesis by structural characterization of the analogue saframycin O C Peng, YM Tang, L Li, W Ding, W Deng, JY Pu, W Liu, GL Tang Science China Chemistry 55, 90-97, 2012 | 11 | 2012 |
| Innate Conformational Dynamics Drive Binding Specificity in Anti-Apoptotic Proteins Mcl-1 and Bcl-2 E Wolf, C Lento, J Pu, BC Dickinson, DJ Wilson Biochemistry 62 (11), 1619-1630, 2023 | 1 | 2023 |
| Proximity-dependent split RNA polymerases as a versatile biosensor platform BC Dickinson, PU Jinyue, J Zinkus US Patent 11,913,081, 2024 | | 2024 |
| A Secreted BBE-Like Enzyme Acting as a Drug-Binding Efflux Carrier Confers Microbial Self-Resistance to Mitomycin C X Chen, R He, A Sun, J Pu, HX Pan, GL Tang Organic Letters, 2024 | | 2024 |
| Chance, contingency, and necessity in the experimental evolution of ancestral proteins VC Xie, J Pu, BPH Metzger, JW Thornton, BC Dickinson bioRxiv, 2020.08. 29.273581, 2020 | | 2020 |
| Front Cover: Evolution of C‐Terminal Modification Tolerance in Full‐Length and Split T7 RNA Polymerase Biosensors (ChemBioChem 12/2019) J Pu, M Disare, BC Dickinson ChemBioChem 20 (12), 1476-1476, 2019 | | 2019 |
Bryan C. DickinsonProfessor, The University of ChicagoVerified email at uchicago.edu
