| Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma P Grabowski, T Kühnel, F Mühr-Wilkenshoff, B Heine, H Stein, M Höpfner, ... British journal of cancer 88 (1), 115-119, 2003 | 337 | 2003 |
| The shunt problem: control of functional shunting in normal and tumour vasculature AR Pries, M Höpfner, F Le Noble, MW Dewhirst, TW Secomb Nature Reviews Cancer 10 (8), 587-593, 2010 | 303 | 2010 |
| EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer A Huether, M Höpfner, V Baradari, D Schuppan, H Scherübl Biochemical pharmacology 70 (11), 1568-1578, 2005 | 220 | 2005 |
| Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma M Höpfner, AP Sutter, A Huether, D Schuppan, M Zeitz, H Scherübl Journal of hepatology 41 (6), 1008-1016, 2004 | 204 | 2004 |
| Structural adaptation and heterogeneity of normal and tumor microvascular networks AR Pries, AJM Cornelissen, AA Sloot, M Hinkeldey, MR Dreher, ... PLoS computational biology 5 (5), e1000394, 2009 | 201 | 2009 |
| Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics A Huether, M Höpfner, AP Sutter, D Schuppan, H Scherübl Journal of hepatology 43 (4), 661-669, 2005 | 198 | 2005 |
| Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer M Höpfner, D Schuppan, H Scherübl World journal of gastroenterology: WJG 14 (1), 1, 2008 | 168 | 2008 |
| Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human colorectal cancer cells K Maaser, M Höpfner, A Jansen, G Weisinger, M Gavish, AP Kozikowski, ... British journal of cancer 85 (11), 1771-1780, 2001 | 160 | 2001 |
| Overexpression of the peripheral benzodiazepine receptor is a relevant prognostic factor in stage III colorectal cancer K Maaser, P Grabowski, AP Sutter, M Höpfner, HD Foss, H Stein, ... Clinical cancer research 8 (10), 3205-3209, 2002 | 152 | 2002 |
| Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells M Höpfner, A Huether, AP Sutter, V Baradari, D Schuppan, H Scherübl Biochemical pharmacology 71 (10), 1435-1448, 2006 | 151 | 2006 |
| Clinically detected gastroenteropancreatic neuroendocrine tumors are on the rise: epidemiological changes in Germany H Scherübl, B Streller, R Stabenow, H Herbst, M Höpfner, C Schwertner, ... World journal of gastroenterology: WJG 19 (47), 9012, 2013 | 147 | 2013 |
| Extracellular nucleotides inhibit growth of human oesophageal cancer cells via P2Y2-receptors K Maaser, M Höpfner, H Kap, AP Sutter, B Barthel, B Von Lampe, M Zeitz, ... British journal of cancer 86 (4), 636-644, 2002 | 137 | 2002 |
| Growth inhibition and apoptosis induced by P2Y2 receptors in human colorectal carcinoma cells: involvement of intracellular calcium and cyclic adenosine … M Höpfner, K Maaser, B Barthel, B Von Lampe, C Hanski, EO Riecken, ... International journal of colorectal disease 16, 154-166, 2001 | 125 | 2001 |
| Apoptosis-modulating drugs for improved cancer therapy M Ocker, M Höpfner European surgical research 48 (3), 111-120, 2012 | 114 | 2012 |
| The insulin-like growth factor receptor 1 is a promising target for novel treatment approaches in neuroendocrine gastrointestinal tumours M Hopfner, V Baradari, A Huether, C Schofl, H Scherubl Endocrine-Related Cancer 13 (1), 135-149, 2006 | 114 | 2006 |
| Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human esophageal cancer cells AP Sutter, K Maaser, M Höpfner, B Barthel, P Grabowski, S Faiss, ... International journal of cancer 102 (4), 318-327, 2002 | 111 | 2002 |
| Cell cycle arrest and apoptosis induction in hepatocellular carcinoma cells by HMG-CoA reductase inhibitors. Synergistic antiproliferative action with ligands of the peripheral … AP Sutter, K Maaser, M Höpfner, A Huether, D Schuppan, H Scherübl Journal of hepatology 43 (5), 808-816, 2005 | 105 | 2005 |
| A novel approach in the treatment of neuroendocrine gastrointestinal tumours. Targeting the epidermal growth factor receptor by gefitinib (ZD1839) M Höpfner, AP Sutter, B Gerst, M Zeitz, H Scherübl British journal of cancer 89 (9), 1766-1775, 2003 | 100 | 2003 |
| Sorafenib alone or as combination therapy for growth control of cholangiocarcinoma A Huether, M Höpfner, V Baradari, D Schuppan, H Scherübl Biochemical pharmacology 73 (9), 1308-1317, 2007 | 94 | 2007 |
| Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells V Baradari, M Höpfner, A Huether, D Schuppan, H Scherübl World journal of gastroenterology: WJG 13 (33), 4458, 2007 | 90 | 2007 |
Detlef SchuppanProfessor of Medicine Mainz University Medical Center, Germany, and Harvard Medical School, Boston, MAVerified email at bidmc.harvard.edu
