| In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates K Musunuru, AC Chadwick, T Mizoguchi, SP Garcia, JE DeNizio, ... Nature 593 (7859), 429-434, 2021 | 482 | 2021 |
| Amino acid addition to Vibrio cholerae LPS establishes a link between surface remodeling in gram-positive and gram-negative bacteria JV Hankins, JA Madsen, DK Giles, JS Brodbelt, MS Trent Proceedings of the National Academy of Sciences 109 (22), 8722-8727, 2012 | 174 | 2012 |
| Ultrafast ultraviolet photodissociation at 193 nm and its applicability to proteomic workflows JA Madsen, DR Boutz, JS Brodbelt Journal of proteome research 9 (8), 4205-4214, 2010 | 137 | 2010 |
| Infrared photo-activation reduces peptide folding and hydrogen atom migration following ETD tandem mass spectrometry AR Ledvina, GC McAlister, MW Gardener, SI Smith, JA Madsen, ... Angewandte Chemie (International ed. in English) 48 (45), 8526, 2009 | 113 | 2009 |
| Elucidation of a novel Vibrio cholerae lipid A secondary hydroxy‐acyltransferase and its role in innate immune recognition JV Hankins, JA Madsen, DK Giles, BM Childers, KE Klose, JS Brodbelt, ... Molecular microbiology 81 (5), 1313-1329, 2011 | 95 | 2011 |
| 193‐nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization JA Madsen, TS Kaoud, KN Dalby, JS Brodbelt Proteomics 11 (7), 1329-1334, 2011 | 90 | 2011 |
| Concurrent Automated Sequencing of the Glycan and Peptide Portions of O-Linked Glycopeptide Anions by Ultraviolet Photodissociation Mass Spectrometry JA Madsen, BJ Ko, H Xu, JA Iwashkiw, SA Robotham, JB Shaw, ... Analytical chemistry 85 (19), 9253-9261, 2013 | 81 | 2013 |
| Tyrosine sulfation in a Gram-negative bacterium SW Han, SW Lee, O Bahar, B Schwessinger, MR Robinson, JB Shaw, ... Nature communications 3 (1), 1153, 2012 | 77 | 2012 |
| IR and UV photodissociation as analytical tools for characterizing lipid A structures JA Madsen, TW Cullen, MS Trent, JS Brodbelt Analytical chemistry 83 (13), 5107-5113, 2011 | 60 | 2011 |
| Comparison of infrared multiphoton dissociation and collision-induced dissociation of supercharged peptides in ion traps JA Madsen, JS Brodbelt Journal of the American Society for Mass Spectrometry 20 (3), 349-358, 2009 | 60 | 2009 |
| Toward the complete characterization of host cell proteins in biotherapeutics via affinity depletions, LC-MS/MS, and multivariate analysis JA Madsen, V Farutin, T Carbeau, S Wudyka, Y Yin, S Smith, J Anderson, ... MAbs 7 (6), 1128-1137, 2015 | 54 | 2015 |
| Simplifying fragmentation patterns of multiply charged peptides by N-terminal derivatization and electron transfer collision activated dissociation JA Madsen, JS Brodbelt Analytical chemistry 81 (9), 3645-3653, 2009 | 53 | 2009 |
| Characterization of unique modification of flagellar rod protein FlgG by Campylobacter jejuni lipid A phosphoethanolamine transferase, linking bacterial locomotion and … TW Cullen, JA Madsen, PL Ivanov, JS Brodbelt, MS Trent Journal of Biological Chemistry 287 (5), 3326-3336, 2012 | 50 | 2012 |
| Infrared multiphoton dissociation of peptide cations in a dual pressure linear ion trap mass spectrometer MW Gardner, SI Smith, AR Ledvina, JA Madsen, JJ Coon, JC Schwartz, ... Analytical chemistry 81 (19), 8109-8118, 2009 | 50 | 2009 |
| The outer membrane of Gram-negative bacteria: lipid A isolation and characterization JV Hankins, JA Madsen, BD Needham, JS Brodbelt, MS Trent Bacterial Cell Surfaces: Methods and Protocols, 239-258, 2013 | 45 | 2013 |
| Systematic comparison of ultraviolet photodissociation and electron transfer dissociation for peptide anion characterization JB Shaw, JA Madsen, H Xu, JS Brodbelt Journal of the American Society for Mass Spectrometry 23 (10), 1707-1715, 2012 | 43 | 2012 |
| High-throughput database search and large-scale negative polarity liquid chromatography–tandem mass spectrometry with ultraviolet photodissociation for complex proteomic samples JA Madsen, H Xu, MR Robinson, AP Horton, JB Shaw, DK Giles, ... Molecular & Cellular Proteomics 12 (9), 2604-2614, 2013 | 42* | 2013 |
| Top-down protein fragmentation by infrared multiphoton dissociation in a dual pressure linear ion trap JA Madsen, MW Gardner, SI Smith, AR Ledvina, JJ Coon, JC Schwartz, ... Analytical chemistry 81 (21), 8677-8686, 2009 | 41 | 2009 |
| Charge‐Site‐Dependent Dissociation of Hydrogen‐Rich Radical Peptide Cations upon Vacuum UV Photoexcitation JA Madsen, RR Cheng, TS Kaoud, KN Dalby, DE Makarov, JS Brodbelt Chemistry–A European Journal 18 (17), 5374-5383, 2012 | 27 | 2012 |
| Asymmetric charge partitioning upon dissociation of DNA duplexes JA Madsen, JS Brodbelt Journal of the American Society for Mass Spectrometry 21 (7), 1144-1150, 2011 | 24 | 2011 |
