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umender sharma
umender sharma
head of Research, Gangagen biotechnologies
Verified email at gangagen.com
Title
Cited by
Cited by
Year
Transcriptional switching in Escherichia coli during stress and starvation by modulation of σ70 activity
UK Sharma, D Chatterji
FEMS microbiology reviews 34 (5), 646-657, 2010
1872010
Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates
M Balganesh, N Dinesh, S Sharma, S Kuruppath, AV Nair, U Sharma
Antimicrobial agents and chemotherapy 56 (5), 2643-2651, 2012
1762012
Deletion analysis of the essentiality of penicillin-binding proteins 1A, 2B and 2X of Streptococcus pneumoniae
CM Kell, UK Sharma, CG Dowson, C Town, TS Balganesh, BG Spratt
FEMS microbiology letters 106 (2), 171-175, 1993
1061993
Antibiofilm activity and synergistic inhibition of Staphylococcus aureus biofilms by bactericidal protein P128 in combination with antibiotics
S Nair, S Desai, N Poonacha, A Vipra, U Sharma
Antimicrobial agents and chemotherapy 60 (12), 7280-7289, 2016
962016
Rv1218c, an ABC Transporter of Mycobacterium tuberculosis with Implications in Drug Discovery
M Balganesh, S Kuruppath, N Marcel, S Sharma, A Nair, U Sharma
Antimicrobial agents and chemotherapy 54 (12), 5167-5172, 2010
962010
Phage-derived lysins as potential agents for eradicating biofilms and persisters
U Sharma, A Vipra, S Channabasappa
Drug Discovery Today 23 (4), 848-856, 2018
882018
Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice
D Awasthy, S Gaonkar, RK Shandil, R Yadav, S Bharath, N Marcel, ...
Microbiology 155 (9), 2978-2987, 2009
692009
Alanine racemase mutants of Mycobacterium tuberculosis require d-alanine for growth and are defective for survival in macrophages and mice
D Awasthy, S Bharath, V Subbulakshmi, U Sharma
Microbiology 158 (2), 319-327, 2012
652012
Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis
D Awasthy, A Ambady, J Bhat, G Sheikh, S Ravishankar, V Subbulakshmi, ...
Microbiology 156 (9), 2691-2701, 2010
492010
Efficient killing of planktonic and biofilm-embedded coagulase-negative staphylococci by bactericidal protein P128
N Poonacha, S Nair, S Desai, D Tuppad, D Hiremath, T Mohan, A Vipra, ...
Antimicrobial Agents and Chemotherapy 61 (8), 10.1128/aac. 00457-17, 2017
452017
Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target
S Ravishankar, A Ambady, D Awasthy, NV Mudugal, S Menasinakai, ...
Tuberculosis 95 (5), 589-598, 2015
442015
Identification of carbohydrate structures as receptors for localised adherent enteropathogenic Escherichia coli
HM Jagannatha, UK Sharma, T Ramaseshan, A Surolia, TS Balganesh
Microbial pathogenesis 11 (4), 259-268, 1991
421991
Novel N-Linked Aminopiperidine-Based Gyrase Inhibitors with Improved hERG and in Vivo Efficacy against Mycobacterium tuberculosis
S Hameed P, V Patil, S Solapure, U Sharma, P Madhavapeddi, ...
Journal of Medicinal Chemistry 57 (11), 4889-4905, 2014
402014
Differential Mechanisms of Binding of Anti-Sigma Factors Escherichia coli Rsd and Bacteriophage T4 AsiA to E. coli RNA Polymerase Lead to Diverse …
UK Sharma, D Chatterji
Journal of bacteriology 190 (10), 3434-3443, 2008
372008
Study of the Interaction between Bacteriophage T4 asiA and Escherichia coli ς70, Using the Yeast Two-Hybrid System: Neutralization of asiA Toxicity to E. coli Cells by …
UK Sharma, S Ravishankar, RK Shandil, PVK Praveen, TS Balganesh
Journal of bacteriology 181 (18), 5855-5859, 1999
361999
Bacteriophage-derived CHAP domain protein, P128, kills Staphylococcus cells by cleaving interpeptide cross-bridge of peptidoglycan
S Sundarrajan, J Raghupatil, A Vipra, N Narasimhaswamy, S Saravanan, ...
Microbiology 160 (10), 2157-2169, 2014
312014
Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection
AG Fraga, G Trigo, RK Murthy, S Akhtar, M Hebbur, AR Pacheco, ...
PLoS neglected tropical diseases 13 (8), e0007113, 2019
302019
Roles of the two type II NADH dehydrogenases in the survival of Mycobacterium tuberculosis in vitro
D Awasthy, A Ambady, A Narayana, S Morayya, U Sharma
Gene 550 (1), 110-116, 2014
292014
Current possibilities and unresolved issues of drug target validation in Mycobacterium tuberculosis
U Sharma
Expert opinion on drug discovery 6 (11), 1171-1186, 2011
272011
Revisiting the essentiality of glutamate racemase in Mycobacterium tuberculosis
S Morayya, D Awasthy, R Yadav, A Ambady, U Sharma
Gene 555 (2), 269-276, 2015
252015
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