Transcriptional switching in Escherichia coli during stress and starvation by modulation of σ70 activity UK Sharma, D Chatterji FEMS microbiology reviews 34 (5), 646-657, 2010 | 187 | 2010 |
Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates M Balganesh, N Dinesh, S Sharma, S Kuruppath, AV Nair, U Sharma Antimicrobial agents and chemotherapy 56 (5), 2643-2651, 2012 | 176 | 2012 |
Deletion analysis of the essentiality of penicillin-binding proteins 1A, 2B and 2X of Streptococcus pneumoniae CM Kell, UK Sharma, CG Dowson, C Town, TS Balganesh, BG Spratt FEMS microbiology letters 106 (2), 171-175, 1993 | 106 | 1993 |
Antibiofilm activity and synergistic inhibition of Staphylococcus aureus biofilms by bactericidal protein P128 in combination with antibiotics S Nair, S Desai, N Poonacha, A Vipra, U Sharma Antimicrobial agents and chemotherapy 60 (12), 7280-7289, 2016 | 96 | 2016 |
Rv1218c, an ABC Transporter of Mycobacterium tuberculosis with Implications in Drug Discovery M Balganesh, S Kuruppath, N Marcel, S Sharma, A Nair, U Sharma Antimicrobial agents and chemotherapy 54 (12), 5167-5172, 2010 | 96 | 2010 |
Phage-derived lysins as potential agents for eradicating biofilms and persisters U Sharma, A Vipra, S Channabasappa Drug Discovery Today 23 (4), 848-856, 2018 | 88 | 2018 |
Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice D Awasthy, S Gaonkar, RK Shandil, R Yadav, S Bharath, N Marcel, ... Microbiology 155 (9), 2978-2987, 2009 | 69 | 2009 |
Alanine racemase mutants of Mycobacterium tuberculosis require d-alanine for growth and are defective for survival in macrophages and mice D Awasthy, S Bharath, V Subbulakshmi, U Sharma Microbiology 158 (2), 319-327, 2012 | 65 | 2012 |
Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis D Awasthy, A Ambady, J Bhat, G Sheikh, S Ravishankar, V Subbulakshmi, ... Microbiology 156 (9), 2691-2701, 2010 | 49 | 2010 |
Efficient killing of planktonic and biofilm-embedded coagulase-negative staphylococci by bactericidal protein P128 N Poonacha, S Nair, S Desai, D Tuppad, D Hiremath, T Mohan, A Vipra, ... Antimicrobial Agents and Chemotherapy 61 (8), 10.1128/aac. 00457-17, 2017 | 45 | 2017 |
Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target S Ravishankar, A Ambady, D Awasthy, NV Mudugal, S Menasinakai, ... Tuberculosis 95 (5), 589-598, 2015 | 44 | 2015 |
Identification of carbohydrate structures as receptors for localised adherent enteropathogenic Escherichia coli HM Jagannatha, UK Sharma, T Ramaseshan, A Surolia, TS Balganesh Microbial pathogenesis 11 (4), 259-268, 1991 | 42 | 1991 |
Novel N-Linked Aminopiperidine-Based Gyrase Inhibitors with Improved hERG and in Vivo Efficacy against Mycobacterium tuberculosis S Hameed P, V Patil, S Solapure, U Sharma, P Madhavapeddi, ... Journal of Medicinal Chemistry 57 (11), 4889-4905, 2014 | 40 | 2014 |
Differential Mechanisms of Binding of Anti-Sigma Factors Escherichia coli Rsd and Bacteriophage T4 AsiA to E. coli RNA Polymerase Lead to Diverse … UK Sharma, D Chatterji Journal of bacteriology 190 (10), 3434-3443, 2008 | 37 | 2008 |
Study of the Interaction between Bacteriophage T4 asiA and Escherichia coli ς70, Using the Yeast Two-Hybrid System: Neutralization of asiA Toxicity to E. coli Cells by … UK Sharma, S Ravishankar, RK Shandil, PVK Praveen, TS Balganesh Journal of bacteriology 181 (18), 5855-5859, 1999 | 36 | 1999 |
Bacteriophage-derived CHAP domain protein, P128, kills Staphylococcus cells by cleaving interpeptide cross-bridge of peptidoglycan S Sundarrajan, J Raghupatil, A Vipra, N Narasimhaswamy, S Saravanan, ... Microbiology 160 (10), 2157-2169, 2014 | 31 | 2014 |
Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection AG Fraga, G Trigo, RK Murthy, S Akhtar, M Hebbur, AR Pacheco, ... PLoS neglected tropical diseases 13 (8), e0007113, 2019 | 30 | 2019 |
Roles of the two type II NADH dehydrogenases in the survival of Mycobacterium tuberculosis in vitro D Awasthy, A Ambady, A Narayana, S Morayya, U Sharma Gene 550 (1), 110-116, 2014 | 29 | 2014 |
Current possibilities and unresolved issues of drug target validation in Mycobacterium tuberculosis U Sharma Expert opinion on drug discovery 6 (11), 1171-1186, 2011 | 27 | 2011 |
Revisiting the essentiality of glutamate racemase in Mycobacterium tuberculosis S Morayya, D Awasthy, R Yadav, A Ambady, U Sharma Gene 555 (2), 269-276, 2015 | 25 | 2015 |