ARP/wARP and molecular replacement A Perrakis, M Harkiolaki, KS Wilson, VS Lamzin Acta Crystallographica Section D: Biological Crystallography 57 (10), 1445-1450, 2001 | 594 | 2001 |
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides M Harkiolaki, SL Holmes, P Svendsen, JW Gregersen, LT Jensen, ... Immunity 30 (3), 348-357, 2009 | 239 | 2009 |
Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76 M Harkiolaki, M Lewitzky, RJC Gilbert, EY Jones, RP Bourette, ... The EMBO journal 22 (11), 2571-2582, 2003 | 145 | 2003 |
Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress L Mendonça, A Howe, JB Gilchrist, Y Sheng, D Sun, ML Knight, ... Nature Communications 12 (1), 4629, 2021 | 122 | 2021 |
Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells Š Bálint, S Müller, R Fischer, BM Kessler, M Harkiolaki, S Valitutti, ... Science 368 (6493), 897-901, 2020 | 116 | 2020 |
Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress VL Hale, JM Watermeyer, F Hackett, G Vizcay-Barrena, C Van Ooij, ... Proceedings of the National Academy of Sciences 114 (13), 3439-3444, 2017 | 107 | 2017 |
The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the “basic module” for dimeric d (C/U) TPases OV Moroz, M Harkiolaki, MY Galperin, AA Vagin, ... Journal of molecular biology 342 (5), 1583-1597, 2004 | 92 | 2004 |
The crystal structure of Trypanosoma cruzi dUTPase reveals a novel dUTP/dUDP binding fold M Harkiolaki, EJ Dodson, V Bernier-Villamor, JP Turkenburg, ... Structure 12 (1), 41-53, 2004 | 89 | 2004 |
Cryo-soft X-ray tomography: using soft X-rays to explore the ultrastructure of whole cells M Harkiolaki, MC Darrow, MC Spink, E Kosior, K Dent, E Duke Emerging topics in life sciences 2 (1), 81-92, 2018 | 86 | 2018 |
Mona/Gads SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II … M Lewitzky, M Harkiolaki, MC Domart, EY Jones, SM Feller Journal of Biological Chemistry 279 (27), 28724-28732, 2004 | 84 | 2004 |
Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2 M Harkiolaki, T Tsirka, M Lewitzky, PC Simister, D Joshi, LE Bird, ... Structure 17 (6), 809-822, 2009 | 82 | 2009 |
3D correlative cryo-structured illumination fluorescence and soft X-ray microscopy elucidates reovirus intracellular release pathway I Kounatidis, ML Stanifer, MA Phillips, P Paul-Gilloteaux, X Heiligenstein, ... Cell 182 (2), 515-530. e17, 2020 | 81 | 2020 |
REMBI: Recommended Metadata for Biological Images—enabling reuse of microscopy data in biology U Sarkans, W Chiu, L Collinson, MC Darrow, J Ellenberg, D Grunwald, ... Nature methods 18 (12), 1418-1422, 2021 | 78 | 2021 |
CryoSIM: super-resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultrastructural imaging MA Phillips, M Harkiolaki, DMS Pinto, RM Parton, A Palanca, ... Optica 7 (7), 802-812, 2020 | 67 | 2020 |
MHC Class I Bound to an Immunodominant Theileria parva Epitope Demonstrates Unconventional Presentation to T Cell Receptors IK Macdonald, M Harkiolaki, L Hunt, T Connelley, AV Carroll, ... PLoS pathogens 6 (10), e1001149, 2010 | 63 | 2010 |
The C-terminal SH3 domain of CRKL as a dynamic dimerization module transiently exposing a nuclear export signal M Harkiolaki, RJC Gilbert, EY Jones, SM Feller Structure 14 (12), 1741-1753, 2006 | 59 | 2006 |
A procedure for setting up high-throughput nanolitre crystallization experiments. II. Crystallization results J Brown, TS Walter, L Carter, NGA Abrescia, AR Aricescu, ... Journal of applied crystallography 36 (2), 315-318, 2003 | 54 | 2003 |
Single-cell chemistry of photoactivatable platinum anticancer complexes EM Bolitho, C Sanchez-Cano, H Shi, PD Quinn, M Harkiolaki, C Imberti, ... Journal of the American Chemical Society 143 (48), 20224-20240, 2021 | 53 | 2021 |
Crystal structure and DNA repair activities of the AP endonuclease from Leishmania major AE Vidal, M Harkiolaki, C Gallego, VM Castillo-Acosta, LM Ruiz-Pérez, ... Journal of molecular biology 373 (4), 827-838, 2007 | 35 | 2007 |
Sample preparation strategies for efficient correlation of 3D SIM and soft X-ray tomography data at cryogenic temperatures CA Okolo, I Kounatidis, J Groen, KL Nahas, S Balint, TM Fish, ... Nature protocols 16 (6), 2851-2885, 2021 | 33 | 2021 |