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Yoan Machado
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Influence of protein fold stability on immunogenicity and its implications for vaccine design
S Scheiblhofer, J Laimer, Y Machado, R Weiss, J Thalhamer
Expert review of vaccines 16 (5), 479-489, 2017
1522017
Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen
Y Machado, R Freier, S Scheiblhofer, T Thalhamer, M Mayr, P Briza, ...
Journal of Allergy and Clinical Immunology 137 (5), 1525-1534, 2016
852016
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome
I Pablos, Y Machado, HCR de Jesus, Y Mohamud, R Kappelhoff, ...
Cell reports 37 (4), 2021
702021
Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction
V Russo, T Klein, DJ Lim, N Solis, Y Machado, S Hiroyasu, L Nabai, ...
Scientific reports 8 (1), 9690, 2018
622018
Isoelectric point optimization using peptide descriptors and support vector machines
Y Perez-Riverol, E Audain, A Millan, Y Ramos, A Sanchez, JA Vizcaíno, ...
Journal of proteomics 75 (7), 2269-2274, 2012
472012
Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy
Y Machado, S Duinkerken, V Hoepflinger, M Mayr, E Korotchenko, ...
Journal of Controlled Release 266, 87-99, 2017
342017
Proteomics based on peptide fractionation by SDS-free PAGE
Y Ramos, E Gutierrez, Y Machado, A Sánchez, L Castellanos-Serra, ...
Journal of proteome research 7 (6), 2427-2434, 2008
252008
Role of B-1 cells in the immune response against an antigen encapsulated into phosphatidylcholine-containing liposomes
Y Cruz-Leal, Y Machado, A López-Requena, L Canet, R Laborde, ...
International immunology 26 (8), 427-437, 2014
242014
New approaches to transcutaneous immunotherapy: targeting dendritic cells with novel allergen conjugates
R Weiss, S Scheiblhofer, Y Machado, J Thalhamer
Current opinion in allergy and clinical immunology 13 (6), 669-676, 2013
242013
TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice
GR Araujo, L Aglas, ER Vaz, Y Machado, S Huber, M Himly, A Duschl, ...
Allergy 75 (4), 882-891, 2020
232020
Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase
PG Jobin, N Solis, Y Machado, PA Bell, NH Kwon, S Kim, CM Overall, ...
Journal of Biological Chemistry 294 (35), 12866-12879, 2019
212019
Effect of structural stability on endolysosomal degradation and T‐cell reactivity of major shrimp allergen tropomyosin
SD Kamath, S Scheiblhofer, CM Johnson, Y Machado, T McLean, AC Taki, ...
Allergy 75 (11), 2909-2919, 2020
202020
Distinct epitope structures of defensin‐like proteins linked to proline‐rich regions give rise to differences in their allergenic activity
I Pablos, S Eichhorn, Y Machado, P Briza, A Neunkirchner, ...
Allergy 73 (2), 431-441, 2018
202018
Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage
PG Jobin, N Solis, Y Machado, PA Bell, SK Rai, NH Kwon, S Kim, ...
Journal of Biological Chemistry 295 (8), 2186-2202, 2020
192020
Potential of nanoparticles for allergen-specific immunotherapy–use of silica nanoparticles as vaccination platform
S Scheiblhofer, Y Machado, A Feinle, J Thalhamer, N Hüsing, R Weiss
Expert opinion on drug delivery 13 (12), 1777-1788, 2016
162016
Physicochemical and biological characterization of 1E10 anti-idiotype vaccine
YJ Machado, Y Rabasa, R Montesinos, J Cremata, V Besada, D Fuentes, ...
BMC biotechnology 11, 1-13, 2011
132011
Two variants of the major serine protease inhibitor from the sea anemone Stichodactyla helianthus, expressed in Pichia pastoris
R García-Fernández, P Ziegelmüller, L González, M Mansur, Y Machado, ...
Protein Expression and Purification 123, 42-50, 2016
122016
Enzymatically releasable polyethylene glycol–host defense peptide conjugates with improved activity and biocompatibility
M Drayton, MA Alford, D Pletzer, EF Haney, Y Machado, HD Luo, ...
Journal of Controlled Release 339, 220-231, 2021
102021
Bio-analytical method based on MALDI-MS analysis for the quantification of CIGB-300 anti-tumor peptide in human plasma
A Cabrales-Rico, BG de la Torre, HE Garay, YJ Machado, JA Gómez, ...
Journal of Pharmaceutical and Biomedical Analysis 105, 107-114, 2015
102015
Phosphocholine-specific antibodies improve T-dependent antibody responses against OVA encapsulated into phosphatidylcholine-containing liposomes
Y Cruz-Leal, A López-Requena, I Lopetegui-González, Y Machado, ...
Frontiers in immunology 7, 180199, 2016
82016
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