Additional acetylcholine (ACh) binding site at α4/α4 interface of (α4β2) 2α4 nicotinic receptor influences agonist sensitivity S Mazzaferro, N Benallegue, A Carbone, F Gasparri, R Vijayan, ... Journal of Biological Chemistry 286 (35), 31043-31054, 2011 | 144 | 2011 |
α4β2 nicotinic acetylcholine receptors: relationships between subunit stoichiometry and function at the single channel level S Mazzaferro, I Bermudez, SM Sine Journal of Biological Chemistry 292 (7), 2729-2740, 2017 | 53 | 2017 |
Non-equivalent ligand selectivity of agonist sites in (α4β2) 2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy S Mazzaferro, F Gasparri, K New, C Alcaino, M Faundez, PI Vasquez, ... Journal of Biological Chemistry 289 (31), 21795-21806, 2014 | 46 | 2014 |
The additional ACh binding site at the α4(+)/α4(−) interface of the (α4β2)2α4 nicotinic ACh receptor contributes to desensitization N Benallegue, S Mazzaferro, C Alcaino, I Bermudez British journal of pharmacology 170 (2), 304-316, 2013 | 35 | 2013 |
Role of the cys loop and transmembrane domain in the allosteric modulation of α4β2 nicotinic acetylcholine receptors C Alcaino, M Musgaard, T Minguez, S Mazzaferro, M Faundez, ... Journal of Biological Chemistry 292 (2), 551-562, 2017 | 32 | 2017 |
Additional acetylcholine (ACh) binding site at a4/a4 interface of (a4b2) 2a4 nicotinic receptor influences agonist sensitivity S Mazzaferro, N Benallegue, A Carbone, F Gasparri, R Vijayan, ... J Biol Chem 286, 31043-31054, 2011 | 23 | 2011 |
Potentiation of a neuronal nicotinic receptor via pseudo-agonist site S Mazzaferro, I Bermudez, SM Sine Cellular and molecular life sciences 76, 1151-1167, 2019 | 20 | 2019 |
NACHO and 14-3-3 promote expression of distinct subunit stoichiometries of the α4β2 acetylcholine receptor S Mazzaferro, ST Whiteman, C Alcaino, A Beyder, SM Sine Cellular and Molecular Life Sciences 78, 1565-1575, 2021 | 15 | 2021 |
Allosteric modulators of α4β2 nicotinic acetylcholine receptors: a new direction for antidepressant drug discovery E Mantione, S Micheloni, C Alcaino, K New, S Mazzaferro, I Bermudez Future Medicinal Chemistry 4 (17), 2217-2230, 2012 | 14 | 2012 |
Structural basis for α-bungarotoxin insensitivity of neuronal nicotinic acetylcholine receptors SM Sine, JR Strikwerda, S Mazzaferro Neuropharmacology 160, 107660, 2019 | 9 | 2019 |
Stoichiometry‐selective modulation of α4β2 nicotinic ACh receptors by divalent cations S Mazzaferro, JR Strikwerda, SM Sine British Journal of Pharmacology 179 (7), 1353-1370, 2022 | 6 | 2022 |
The additional acetylcholine binding site at the α4 (+)/α4 (−) interface of the (α4β2) 2α4 nicotinic acetylcholine receptor contributes to desensitisation N Benallegue, S Mazzaferro, C Alcaino, I Bermudez Br J Pharmacol 170, 304-316, 2013 | 6 | 2013 |
The fifth subunit of the (α4β2)2β2 nicotinic ACh receptor modulates maximal ACh responses K New, SG Del Villar, S Mazzaferro, C Alcaino, I Bermudez British Journal of Pharmacology 175 (11), 1822-1837, 2018 | 5 | 2018 |
Genetic Variant in Nicotinic Receptor α4-Subunit Causes Sleep-Related Hyperkinetic Epilepsy via Increased Channel Opening SMS Simone Mazzaferro, Deborah J. Msekela, Edward C. Cooper, Atul Maheshwari Int. J. Mol. Sci. 2022, 23(20), 12124; https://doi.org/10.3390/ijms232012124 …, 2022 | 4* | 2022 |
Differentiation, Transcriptomic Profiling, and Calcium Imaging of Human Hypothalamic Neurons HJC Chen, S Mazzaferro, T Tian, I Mali, FT Merkle Current protocols 3 (6), e786, 2023 | 3 | 2023 |
An analogue of the Prolactin Releasing Peptide reduces obesity and promotes adult neurogenesis SKM Jörgensen, A Karnošová, S Mazzaferro, O Rowley, HJC Chen, ... EMBO reports 25 (1), 351-377, 2024 | 2 | 2024 |
Profiling human hypothalamic neurons reveals a candidate combination drug therapy for weight loss HJC Chen, A Yang, S Mazzaferro, I Mali, O Cahn, K Kentistou, C Rowley, ... bioRxiv, 2023.07. 18.549357, 2023 | 1 | 2023 |
Structural bases for stoichiometry‐selective calcium potentiation of a neuronal nicotinic receptor S Mazzaferro, G Kang, K Natarajan, RE Hibbs, SM Sine British Journal of Pharmacology, 2024 | | 2024 |
GLP1R agonists activate human POMC neurons S Mazzaferro, HJC Chen, O Cahn, A Yang, D Shepilov, J Chen, C Alcaino, ... bioRxiv, 2024.04. 02.587825, 2024 | | 2024 |
THE FIFTH SUBUNIT MODULATES THE FUNCTION OF CANONICAL AGONIST SITES IN alpha 4 beta 2 NICOTINIC RECEPTORS GS del Villar, K New, S Mazzaferro, S Bermudez BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 121, 47-47, 2017 | | 2017 |