Targeting p53 for novel anticancer therapy Z Wang, Y Sun Translational oncology 3 (1), 1-12, 2010 | 346 | 2010 |
p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis PS Kho, Z Wang, L Zhuang, Y Li, JL Chew, HH Ng, ET Liu, Q Yu Journal of Biological Chemistry 279 (20), 21183-21192, 2004 | 175 | 2004 |
Protective role of salidroside against aging in a mouse model induced by D-galactose MAO Gen-Xiang, D Hong-Bin, Y Long-Guo, LI Dian-Dong, YYY Li, ... Biomedical and Environmental Sciences 23 (2), 161-166, 2010 | 141 | 2010 |
Cardiac glycosides induce autophagy in human non-small cell lung cancer cells through regulation of dual signaling pathways Y Wang, Q Qiu, JJ Shen, DD Li, XJ Jiang, SY Si, RG Shao, Z Wang The international journal of biochemistry & cell biology 44 (11), 1813-1824, 2012 | 116 | 2012 |
Cardiac glycosides inhibit p53 synthesis by a mechanism relieved by Src or MAPK inhibition Z Wang, M Zheng, Z Li, R Li, L Jia, X Xiong, N Southall, S Wang, M Xia, ... Cancer research 69 (16), 6556-6564, 2009 | 112 | 2009 |
Salidroside protects human fibroblast cells from premature senescence induced by H2O2 partly through modulating oxidative status G Mao, Y Wang, Q Qiu, H Deng, L Yuan, R Li, D Song, YY Li, D Li, ... Mechanisms of ageing and development 131 (11-12), 723-731, 2010 | 103 | 2010 |
Role of insulin/insulin-like growth factor 1 signaling pathway in longevity CL Cheng, TQ Gao, Z Wang, DD Li World journal of gastroenterology: WJG 11 (13), 1891, 2005 | 65 | 2005 |
Activation of astrocytes by advanced glycation end products: cytokines induction and nitric oxide release Z Wang, DD Li, YY Liang, DS Wang, NS Cai Acta Pharmacologica Sinica 23 (11), 974-980, 2002 | 64 | 2002 |
The E3 ligase RING1 targets p53 for degradation and promotes cancer cell proliferation and survival J Shen, P Li, X Shao, Y Yang, X Liu, M Feng, Q Yu, R Hu, Z Wang Cancer research 78 (2), 359-371, 2018 | 57 | 2018 |
Src mediates extracellular signal‐regulated kinase 1/2 activation and autophagic cell death induced by cardiac glycosides in human non‐small cell lung cancer cell lines Y Wang, Y Zhan, R Xu, R Shao, J Jiang, Z Wang Molecular Carcinogenesis 54 (S1), E26-E34, 2015 | 57 | 2015 |
Design, synthesis and biological evaluation of novel benzimidazole-2-substituted phenyl or pyridine propyl ketene derivatives as antitumour agents L Wu, Z Jiang, J Shen, H Yi, Y Zhan, M Sha, Z Wang, S Xue, Z Li European Journal of Medicinal Chemistry 114, 328-336, 2016 | 54 | 2016 |
Salidroside stimulates osteoblast differentiation through BMP signaling pathway JJ Chen, NF Zhang, GX Mao, XB He, YC Zhan, HB Deng, DQ Song, DD Li, ... Food and chemical toxicology 62, 499-505, 2013 | 54 | 2013 |
BET inhibition attenuates Helicobacter pylori–induced inflammatory response by suppressing inflammatory gene transcription and enhancer activation J Chen, Z Wang, X Hu, R Chen, J Romero-Gallo, RM Peek, LF Chen The Journal of Immunology 196 (10), 4132-4142, 2016 | 51 | 2016 |
Effects of AGEs on oxidation stress and antioxidation abilities in cultured astrocytes JM Jiang, Z Wang, DD Li Biomedical and Environmental Sciences 17 (1), 79-86, 2004 | 44 | 2004 |
Non-caspase-mediated apoptosis contributes to the potent cytotoxicity of the enediyne antibiotic lidamycin toward human tumor cells Z Wang, Q He, Y Liang, D Wang, YY Li, D Li Biochemical pharmacology 65 (11), 1767-1775, 2003 | 36 | 2003 |
DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis M Sha, G Mao, G Wang, Y Chen, X Wu, Z Wang Acta Pharmaceutica Sinica B 5 (3), 188-193, 2015 | 35 | 2015 |
Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2–p53 interaction G Zheng, J Shen, Y Zhan, H Yi, S Xue, Z Wang, X Ji, Z Li European Journal of Medicinal Chemistry 81, 277-288, 2014 | 33 | 2014 |
P53 dependent and independent apoptosis induced by lidamycin in human colorectal cancer cells L Chen, J Jiang, C Cheng, A Yang, Q He, D Li, Z Wang Cancer Biology & Therapy 6 (6), 965-973, 2007 | 33 | 2007 |
Small molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways X Zhao, J Chen, G Zhang, Y Wang, S Si, LF Chen, Z Wang Scientific reports 7 (1), 10397, 2017 | 32 | 2017 |
Ouabain impairs cancer metabolism and activates AMPK-Src signaling pathway in human cancer cell lines J Shen, Y Zhan, H Li, Z Wang Acta Pharmacologica Sinica 41 (1), 110-118, 2020 | 30 | 2020 |