An update on the genetics of hyperuricaemia and gout TJ Major, N Dalbeth, EA Stahl, TR Merriman Nature Reviews Rheumatology 14 (6), 341-353, 2018 | 245 | 2018 |
Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts TJ Major, RK Topless, N Dalbeth, TR Merriman bmj 363, 2018 | 206 | 2018 |
Mendelian randomization analysis associates increased serum urate, due to genetic variation in uric acid transporters, with improved renal function K Hughes, T Flynn, J De Zoysa, N Dalbeth, TR Merriman Kidney international 85 (2), 344-351, 2014 | 97 | 2014 |
Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people … M Krishnan, TJ Major, RK Topless, O Dewes, L Yu, JMD Thompson, ... Diabetologia 61, 1603-1613, 2018 | 84 | 2018 |
Mendelian randomization analysis to examine for a causal effect of urate on bone mineral density N Dalbeth, R Topless, T Flynn, M Cadzow, MJ Bolland, TR Merriman Journal of Bone and Mineral Research 30 (6), 985-991, 2015 | 55 | 2015 |
Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case … TJ Flynn, A Phipps-Green, JE Hollis-Moffatt, ME Merriman, R Topless, ... Arthritis research & therapy 15, 1-11, 2013 | 55 | 2013 |
Mendelian randomization provides no evidence for a causal role of serum urate in increasing serum triglyceride levels H Rasheed, K Hughes, TJ Flynn, TR Merriman Circulation: Cardiovascular Genetics 7 (6), 830-837, 2014 | 45 | 2014 |
Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control J Boocock, M Leask, Y Okada, ... Human molecular genetics 29 (6), 923-943, 2020 | 42 | 2020 |
Positive association of tomato consumption with serum urate: support for tomato consumption as an anecdotal trigger of gout flares TJ Flynn, M Cadzow, N Dalbeth, PB Jones, LK Stamp, JH Hindmarsh, ... BMC musculoskeletal disorders 16, 1-8, 2015 | 42 | 2015 |
Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout R Wrigley, AJ Phipps-Green, RK Topless, TJ Major, M Cadzow, P Riches, ... Arthritis research & therapy 22, 1-10, 2020 | 37 | 2020 |
The relationship between ferritin and urate levels and risk of gout T Fatima, C McKinney, TJ Major, LK Stamp, N Dalbeth, C Iverson, ... Arthritis research & therapy 20, 1-9, 2018 | 36 | 2018 |
Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout … A Nakayama, M Nakatochi, Y Kawamura, K Yamamoto, H Nakaoka, ... Annals of the rheumatic diseases 79 (5), 657-665, 2020 | 33 | 2020 |
The comparative effect of exposure to various risk factors on the risk of hyperuricaemia: diet has a weak causal effect RKG Topless, TJ Major, JC Florez, JN Hirschhorn, M Cadzow, N Dalbeth, ... Arthritis research & therapy 23, 1-12, 2021 | 26 | 2021 |
Mediation analysis to understand genetic relationships between habitual coffee intake and gout J Hutton, T Fatima, TJ Major, R Topless, LK Stamp, TR Merriman, ... Arthritis Research & Therapy 20, 1-9, 2018 | 20 | 2018 |
Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women RK Topless, TJ Flynn, M Cadzow, LK Stamp, N Dalbeth, MA Black, ... Frontiers in genetics 6, 162450, 2015 | 20 | 2015 |
Aotearoa New Zealand Māori and Pacific Population-amplified Gout Risk Variants: CLNK Is a Separate Risk Gene at the SLC2A9 Locus A Ji, A Shaukat, R Takei, M Bixley, M Cadzow, RK Topless, TJ Major, ... The Journal of Rheumatology 48 (11), 1736-1744, 2021 | 13 | 2021 |
Association analysis of the beta-3 adrenergic receptor Trp64Arg (rs4994) polymorphism with urate and gout T Fatima, S Altaf, A Phipps-Green, R Topless, TJ Flynn, LK Stamp, ... Rheumatology international 36, 255-261, 2016 | 13 | 2016 |
Association of gout polygenic risk score with age at disease onset and Tophaceous disease in European and Polynesian men with gout NA Sumpter, R Takei, M Cadzow, RKG Topless, AJ Phipps‐Green, ... Arthritis & Rheumatology 75 (5), 816-825, 2023 | 11 | 2023 |
Dietary sodium modifies serum uric acid concentrations in humans AS Todd, RJ Walker, RJ MacGinley, J Kelly, TR Merriman, TJ Major, ... American journal of hypertension 30 (12), 1196-1202, 2017 | 11 | 2017 |
Trans-ancestral dissection of urate- and gout-associated major loci SLC2A9 and ABCG2 reveals primate-specific regulatory effects R Takei, M Cadzow, D Markie, M Bixley, A Phipps-Green, TJ Major, C Li, ... Journal of human genetics 66 (2), 161-169, 2021 | 7* | 2021 |