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Nicole Krentz
Nicole Krentz
Assistant Professor, Faculty of Pharmaceutical Sciences, University of British Columbia
Verified email at ubc.ca
Title
Cited by
Cited by
Year
Insights into pancreatic islet cell dysfunction from type 2 diabetes mellitus genetics
NAJ Krentz, AL Gloyn
Nature Reviews Endocrinology 16 (4), 202-212, 2020
1152020
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
OP Dwivedi, M Lehtovirta, B Hastoy, V Chandra, NAJ Krentz, S Kleiner, ...
Nature genetics 51 (11), 1596-1606, 2019
1122019
Single-cell transcriptome profiling of mouse and hESC-derived pancreatic progenitors
NAJ Krentz, MYY Lee, EE Xu, SLJ Sproul, A Maslova, S Sasaki, FC Lynn
Stem cell reports 11 (6), 1551-1564, 2018
1112018
Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors
NAJ Krentz, D van Hoof, Z Li, A Watanabe, M Tang, C Nian, MS German, ...
Developmental cell 41 (2), 129-142. e6, 2017
932017
TALEN/CRISPR-Mediated eGFP Knock-In Add-On at the OCT4 Locus Does Not Impact Differentiation of Human Embryonic Stem Cells towards Endoderm
NAJ Krentz, C Nian, FC Lynn
PloS one 9 (12), e114275, 2014
432014
Npas4 Is a Novel Activity–Regulated Cytoprotective Factor in Pancreatic β-Cells
PV Sabatini, NAJ Krentz, B Zarrouki, CY Westwell-Roper, C Nian, RA Uy, ...
Diabetes 62 (8), 2808-2820, 2013
402013
SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models
EE Xu, NAJ Krentz, S Tan, SZ Chow, M Tang, C Nian, FC Lynn
Diabetologia 58, 1013-1023, 2015
362015
Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering
NAJ Krentz, LD Shea, MO Huising, JAM Shaw
The Lancet Diabetes & Endocrinology 9 (10), 708-724, 2021
252021
TrxG complex catalytic and non-catalytic activity play distinct roles in pancreas progenitor specification and differentiation
SA Campbell, CL McDonald, NAJ Krentz, FC Lynn, BG Hoffman
Cell reports 28 (7), 1830-1844. e6, 2019
132019
77-Ins2 Gene Bursting Activity Defines a Mature β-Cell State
H Modi, J Chu, S Skovsø, C Ellis, NAJ Krentz, Y Zhao, HH Cen, ...
Canadian Journal of Diabetes 44 (7), S31, 2020
102020
A regulatory network controls nephrocan expression and midgut patterning
J Hou, W Wei, RS Saund, P Xiang, TJ Cunningham, Y Yi, O Alder, ...
Development 141 (19), 3772-3781, 2014
82014
Dynamic Ins2 Gene Activity Defines β-Cell Maturity States
CMJ Chu, H Modi, C Ellis, NAJ Krentz, S Skovsø, YB Zhao, H Cen, ...
Diabetes 71 (12), 2612-2631, 2022
62022
Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression
KK Mattis, NAJ Krentz, C Metzendorf, F Abaitua, AF Spigelman, H Sun, ...
Diabetologia 66 (4), 674-694, 2023
52023
PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development
HH Lau, NAJ Krentz, F Abaitua, M Perez-Alcantara, JW Chan, J Ajeian, ...
Nature Communications 14 (1), 6119, 2023
32023
Improvements in stem cell to beta-cell differentiation for the treatment of diabetes
NAJ Krentz
Journal of Immunology and Regenerative Medicine 12, 100043, 2021
32021
Dynamic Ins2 gene activity defines β cell maturity states
H Modi, CM Jamie Chu, S Skovsø, C Ellis, NAJ Krentz, YB Zhao, H Cen, ...
bioRxiv, 702589, 2019
22019
Electrophysiological characterisation of iPSC-derived human β-like cells and an SLC30A8 disease model
M Jaffredo, NAJ Krentz, B Champon, CE Duff, S Nawaz, N Beer, ...
bioRxiv, 2023
12023
Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding
TA Alghamdi, NAJ Krentz, N Smith, AF Spigelman, V Rajesh, A Jha, ...
Molecular Metabolism 66, 101621, 2022
12022
PAX4 loss of function alters human endocrine cell development and influences diabetes risk
HH Lau, NAJ Krentz, F Abaitua, M Perez-Alcantara, JW Chan, J Ajeian, ...
bioRxiv, 2022.05. 15.491987, 2022
12022
Imaging Ins2 gene activity and single-cell RNA sequencing reveal heterogeneous beta cell states
H Modi, H Cen, S Skovso, X Hu, N Krentz, D Dionne, S Xuan, M Huising, ...
DIABETOLOGIA 61, S17-S17, 2018
12018
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