Defects in DNA repair genes predict response to neoadjuvant cisplatin-based chemotherapy in muscle-invasive bladder cancer ER Plimack, RL Dunbrack, TA Brennan, MD Andrake, Y Zhou, ... European urology 68 (6), 959-967, 2015 | 454 | 2015 |
Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases RJ Thapa, S Nogusa, P Chen, JL Maki, A Lerro, M Andrake, GF Rall, ... Proceedings of the National Academy of Sciences 110 (33), E3109-E3118, 2013 | 368 | 2013 |
DAI senses influenza A virus genomic RNA and activates RIPK3-dependent cell death RJ Thapa, JP Ingram, KB Ragan, S Nogusa, DF Boyd, AA Benitez, ... Cell host & microbe 20 (5), 674-681, 2016 | 343 | 2016 |
Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site X Wang, Y Wang, Y Zhou, E Hendron, S Mancarella, MD Andrake, ... Biophysical Journal 106 (2), 314a, 2014 | 185 | 2014 |
Retroviral integrase, putting the pieces together MD Andrake, AM Skalka Journal of Biological Chemistry 271 (33), 19633-19636, 1996 | 185 | 1996 |
Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity G Bujacz, J Alexandratos, A Wlodawer, G Merkel, M Andrake, RA Katz, ... Journal of Biological Chemistry 272 (29), 18161-18168, 1997 | 180 | 1997 |
HMG protein family members stimulate human immunodeficiency virus type 1 and avian sarcoma virus concerted DNA integration in vitro P Hindmarsh, T Ridky, R Reeves, M Andrake, AM Skalka, J Leis Journal of virology 73 (4), 2994-3003, 1999 | 152 | 1999 |
Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells G Banumathy, N Somaiah, R Zhang, Y Tang, J Hoffmann, M Andrake, ... Molecular and cellular biology 29 (3), 758-770, 2009 | 135 | 2009 |
A modified HSP70 inhibitor shows broad activity as an anticancer agent GM Balaburski, JIJ Leu, N Beeharry, S Hayik, MD Andrake, G Zhang, ... Molecular Cancer Research 11 (3), 219-229, 2013 | 116 | 2013 |
The human protein PRR14 tethers heterochromatin to the nuclear lamina during interphase and mitotic exit A Poleshko, KM Mansfield, CC Burlingame, MD Andrake, NR Shah, ... Cell reports 5 (2), 292-301, 2013 | 111 | 2013 |
Small-molecule disruption of RAD52 rings as a mechanism for precision medicine in BRCA-deficient cancers G Chandramouly, S McDevitt, K Sullivan, T Kent, A Luz, JF Glickman, ... Chemistry & biology 22 (11), 1491-1504, 2015 | 108 | 2015 |
A new model for allosteric regulation of phenylalanine hydroxylase: implications for disease and therapeutics EK Jaffe, L Stith, SH Lawrence, M Andrake, RL Dunbrack Jr Archives of biochemistry and biophysics 530 (2), 73-82, 2013 | 99 | 2013 |
Multimerization determinants reside in both the catalytic core and C terminus of avian sarcoma virus integrase MD Andrake, AM Skalka Journal of Biological Chemistry 270 (49), 29299-29306, 1995 | 95 | 1995 |
DNA polymerase of bacteriophage T4 is an autogenous translational repressor. M Andrake, N Guild, T Hsu, L Gold, C Tuerk, J Karam Proceedings of the National Academy of Sciences 85 (21), 7942-7946, 1988 | 87 | 1988 |
Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses M Brusilovsky, M Cordoba, B Rosental, O Hershkovitz, MD Andrake, ... The Journal of Immunology 191 (10), 5256-5267, 2013 | 52 | 2013 |
Mapping the epitope of an inhibitory monoclonal antibody to the C-terminal DNA-binding domain of HIV-1 integrase J Yi, H Cheng, MD Andrake, RL Dunbrack, H Roder, AM Skalka Journal of Biological Chemistry 277 (14), 12164-12174, 2002 | 50 | 2002 |
Kinase-mediated changes in nucleosome conformation trigger chromatin decondensation via poly (ADP-ribosyl) ation CJ Thomas, E Kotova, M Andrake, J Adolf-Bryfogle, R Glaser, C Regnard, ... Molecular cell 53 (5), 831-842, 2014 | 48 | 2014 |
A bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export C Li, M Andrake, R Dunbrack, GH Enders Molecular and cellular biology 30 (1), 116-130, 2010 | 46 | 2010 |
Numb independently antagonizes Sanpodo membrane targeting and Notch signaling in Drosophila sensory organ precursor cells X Tong, D Zitserman, I Serebriiskii, M Andrake, R Dunbrack, F Roegiers Molecular Biology of the Cell 21 (5), 802-810, 2010 | 45 | 2010 |
Genetic variants that predispose to DNA double-strand breaks in lymphocytes from a subset of patients with familial colorectal carcinomas S Arora, H Yan, I Cho, HY Fan, B Luo, X Gai, DL Bodian, JG Vockley, ... Gastroenterology 149 (7), 1872-1883. e9, 2015 | 39 | 2015 |