The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors M Mahameed, T Wilhelm, O Darawshi, A Obiedat, WS Tommy, C Chintha, ... Cell death & disease 10 (4), 300, 2019 | 75 | 2019 |
Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1 A Obiedat, E Seidel, M Mahameed, O Bernani, P Tsukerman, K Voutetakis, ... The FASEB Journal 33 (3), 3481-3495, 2019 | 34 | 2019 |
Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy M Mahameed, S Boukeileh, A Obiedat, O Darawshi, P Dipta, A Rimon, ... Nature communications 11 (1), 1304, 2020 | 25 | 2020 |
The integrated stress response promotes B7H6 expression A Obiedat, Y Charpak-Amikam, J Tai-Schmiedel, E Seidel, M Mahameed, ... Journal of Molecular Medicine 98, 135-148, 2020 | 25 | 2020 |
Aripiprazole cytotoxicity coincides with activation of the unfolded protein response in human hepatic cells F Forno, Y Maatuf, S Boukeileh, P Dipta, M Mahameed, O Darawshi, ... Journal of Pharmacology and Experimental Therapeutics 374 (3), 452-461, 2020 | 14 | 2020 |
Engineering a rapid insulin release system controlled by oral drug administration M Mahameed, S Xue, BA Stefanov, GCE Hamri, M Fussenegger Advanced Science 9 (9), 2105619, 2022 | 10 | 2022 |
Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation [S] T Weiss-Sadan, G Itzhak, F Kaschani, Z Yu, M Mahameed, A Anaki, ... Molecular & Cellular Proteomics 18 (7), 1330-1344, 2019 | 9 | 2019 |
Engineering receptors in the secretory pathway for orthogonal signalling control M Mahameed, P Wang, S Xue, M Fussenegger Nature Communications 13 (1), 7350, 2022 | 5 | 2022 |
An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma O Darawshi, B Muz, SG Naamat, B Praveen, M Mahameed, K Goldberg, ... Cell death & disease 13 (11), 969, 2022 | 5 | 2022 |
Endoplasmic Reticulum Homeostasis Regulates TLR4 Expression and Signaling in Mast Cells S Boukeileh, O Darawshi, M Shmuel, M Mahameed, T Wilhelm, P Dipta, ... International Journal of Molecular Sciences 23 (19), 11826, 2022 | 4 | 2022 |
Towards enhancing therapeutic glycoprotein bioproduction: Interventions in the PI3K/AKT/mTOR Pathway M Mahameed, A Sulieman, D Alkam, B Tirosh Cell Structure and Function 44 (2), 75-83, 2019 | 4 | 2019 |
Engineering CHO cells with an oncogenic KIT improves cells growth, resilience to stress, and productivity M Mahameed, B Tirosh Biotechnology and Bioengineering 114 (11), 2560-2570, 2017 | 4 | 2017 |
Engineering autonomous closed-loop designer cells for disease therapy M Mahameed, M Fussenegger Iscience 25 (3), 2022 | 3 | 2022 |
Low concentrations of cadmium chloride promotes protein translation and improve cell line productivity M Mahameed, A Obiedat, G Beck, JC Johnson, B Tirosh Biotechnology and Bioengineering 116 (3), 569-580, 2019 | 3 | 2019 |
Dataset related to article: Aripiprazole cytotoxicity coincides with activation of the unfolded protein response in human hepatic cells F Forno, Y Maatuf, S Boukeileh, P Dipta, M Mahameed, O Darawshi, ... | | 2021 |
Erratum: Aripiprazole Cytotoxicity Coincides with Activation of the Unfolded Protein Response in Human Hepatic Cells (Journal of Pharmacology and Experimental Therapeutics … F Forno, Y Maatuf, S Boukeileh, P Dipta, M Mahameed, O Darawshi, ... Erratum: Aripiprazole Cytotoxicity Coincides with Activation of the Unfolded …, 2020 | | 2020 |