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Santosh Kumar Jha
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Direct evidence for a dry molten globule intermediate during the unfolding of a small protein
SK Jha, JB Udgaonkar
Proceedings of the National Academy of Sciences 106 (30), 12289-12294, 2009
1412009
Continuous dissolution of structure during the unfolding of a small protein
SK Jha, D Dhar, G Krishnamoorthy, JB Udgaonkar
Biophysical Journal 96 (3), 81a, 2009
882009
Kinetic evidence for a two-stage mechanism of protein denaturation by guanidinium chloride
SK Jha, S Marqusee
Proceedings of the National Academy of Sciences 111 (13), 4856-4861, 2014
852014
Direct measurement of the protein response to an electrostatic perturbation that mimics the catalytic cycle in ketosteroid isomerase
SK Jha, M Ji, KJ Gaffney, SG Boxer
Proceedings of the National Academy of Sciences 108 (40), 16612-16617, 2011
542011
Exploring the cooperativity of the fast folding reaction of a small protein using pulsed thiol labeling and mass spectrometry
SK Jha, JB Udgaonkar
Journal of biological chemistry 282 (52), 37479-37491, 2007
492007
Evidence for dry molten globule-like domains in the pH-induced equilibrium folding intermediate of a multidomain protein
N Acharya, P Mishra, SK Jha
The Journal of Physical Chemistry Letters 7 (1), 173-179, 2016
352016
Free energy barriers in protein folding and unfolding reactions
SK Jha, JB Udgaonkar
Current Science, 457-475, 2010
342010
Identification of multiple folding pathways of monellin using pulsed thiol labeling and mass spectrometry
SK Jha, A Dasgupta, P Malhotra, JB Udgaonkar
Biochemistry 50 (15), 3062-3074, 2011
312011
Site-Specific Measurement of Water Dynamics in the Substrate Pocket of Ketosteroid Isomerase Using Time-Resolved Vibrational Spectroscopy
SK Jha, M Ji, KJ Gaffney, SG Boxer
The Journal of Physical Chemistry B 116 (37), 11414–11421, 2012
232012
The folding and aggregation energy landscapes of tethered RRM domains of human TDP-43 are coupled via a metastable molten globule-like oligomer
M Pillai, SK Jha
Biochemistry 58 (6), 608-620, 2018
202018
Early metastable assembly during the stress-induced formation of worm-like amyloid fibrils of nucleic acid binding domains of TDP-43
M Pillai, SK Jha
Biochemistry 59 (3), 315-328, 2020
182020
Slow motion protein dance visualized using red-edge excitation shift of a buried fluorophore
P Mishra, SK Jha
The Journal of Physical Chemistry B 123 (6), 1256-1264, 2019
152019
Protonation–deprotonation switch controls the amyloid-like misfolding of nucleic-acid-binding domains of TDP-43
D Patni, SK Jha
The Journal of Physical Chemistry B 125 (30), 8383-8394, 2021
122021
An alternatively packed dry molten globule-like Intermediate in the native state ensemble of a multidomain protein
P Mishra, SK Jha
The Journal of Physical Chemistry B 121 (40), 9336-9347, 2017
112017
Characterization of deamidation of barstar using electrospray ionization quadrupole time‐of‐flight mass spectrometry, which stabilizes an equilibrium unfolding intermediate
SK Jha, PD Deepalakshmi, JB Udgaonkar
Protein Science 21, 633-646, 2012
112012
Effect of In Vitro Solvation Conditions on Inter- and Intramolecular Assembly of Full-Length TDP-43
AA Doke, SK Jha
The Journal of Physical Chemistry B 126 (26), 4799-4813, 2022
82022
The native state conformational heterogeneity in the energy landscape of protein folding
P Mishra, SK Jha
Biophysical Chemistry 283, 106761, 2022
72022
A dry molten globule-like intermediate during the base-induced unfolding of a multidomain protein
N Acharya, P Mishra, SK Jha
Physical Chemistry Chemical Physics 19 (44), 30207-30216, 2017
72017
Dry molten globule-like intermediates in protein folding, function, and disease
N Acharya, SK Jha
The Journal of Physical Chemistry B 126 (43), 8614-8622, 2022
62022
Shapeshifter TDP-43: Molecular mechanism of structural polymorphism, aggregation, phase separation and their modulators
AA Doke, SK Jha
Biophysical Chemistry 295, 106972, 2023
52023
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