Follow
Javier Santos Aberturas
Javier Santos Aberturas
Postdoctoral Researcher, John Innes Centre
Verified email at unileon.es
Title
Cited by
Cited by
Year
PimM, a PAS domain positive regulator of pimaricin biosynthesis in Streptomyces natalensis
N Anton, J Santos-Aberturas, MV Mendes, SM Guerra, JF Martín, ...
Microbiology 153 (9), 3174-3183, 2007
1322007
Uncovering the unexplored diversity of thioamidated ribosomal peptides in Actinobacteria using the RiPPER genome mining tool
J Santos-Aberturas, G Chandra, L Frattaruolo, R Lacret, TH Pham, ...
Nucleic Acids Research 47 (9), 4624-4637, 2019
1172019
Biotechnological production and application of the antibiotic pimaricin: biosynthesis and its regulation
JF Aparicio, EG Barreales, TD Payero, CM Vicente, A de Pedro, ...
Applied microbiology and biotechnology 100 (1), 61-78, 2016
1112016
Fully automatized high‐throughput enzyme library screening using a robotic platform
M Dörr, MPC Fibinger, D Last, S Schmidt, J Santos‐Aberturas, D Böttcher, ...
Biotechnology and Bioengineering 113 (7), 1421-1432, 2016
1022016
Cholesterol oxidases act as signaling proteins for the biosynthesis of the polyene macrolide pimaricin
MV Mendes, E Recio, N Antón, SM Guerra, J Santos-Aberturas, JF Martín, ...
Chemistry & biology 14 (3), 279-290, 2007
822007
Dissecting bottromycin biosynthesis using comparative untargeted metabolomics
WJK Crone, NM Vior, J Santos‐Aberturas, LG Schmitz, FJ Leeper, ...
Angewandte Chemie 128 (33), 9791-9795, 2016
722016
Functional conservation of PAS–LuxR transcriptional regulators in polyene macrolide biosynthesis
J Santos-Aberturas, TD Payero, CM Vicente, SM Guerra, C Canibano, ...
Metabolic engineering 13 (6), 756-767, 2011
712011
Structure of cytochrome P450 PimD suggests epoxidation of the polyene macrolide pimaricin occurs via a hydroperoxoferric intermediate
PM Kells, H Ouellet, J Santos-Aberturas, JF Aparicio, LM Podust
Chemistry & biology 17 (8), 841-851, 2010
652010
Draft genome of Streptomyces tsukubaensis NRRL 18488, the producer of the clinically important immunosuppressant tacrolimus (FK506)
C Barreiro, C Prieto, A Sola-Landa, E Solera, M Martínez-Castro, ...
Journal of bacteriology 194 (14), 3756-3757, 2012
622012
Molecular control of polyene macrolide biosynthesis: direct binding of the regulator PimM to eight promoters of pimaricin genes and identification of binding boxes
J Santos-Aberturas, CM Vicente, SM Guerra, TD Payero, JF Martín, ...
Journal of biological chemistry 286 (11), 9150-9161, 2011
622011
FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis
D Goranovič, M Blažič, V Magdevska, J Horvat, E Kuščer, T Polak, ...
BMC microbiology 12, 1-15, 2012
562012
PimT, an amino acid exporter controls polyene production via secretion of the quorum sensing pimaricin-inducer PI-factor in Streptomyces natalensis
CM Vicente, J Santos-Aberturas, SM Guerra, TD Payero, JF Martín, ...
Microbial cell factories 8, 1-13, 2009
502009
PAS-LuxR transcriptional control of filipin biosynthesis in S. avermitilis
CM Vicente, J Santos-Aberturas, TD Payero, EG Barreales, A de Pedro, ...
Applied microbiology and biotechnology 98, 9311-9324, 2014
452014
In-depth high-throughput screening of protein engineering libraries by split-GFP direct crude cell extract data normalization
J Santos-Aberturas, M Dörr, GS Waldo, UT Bornscheuer
Chemistry & biology 22 (10), 1406-1414, 2015
442015
LAL Regulators SCO0877 and SCO7173 as Pleiotropic Modulators of Phosphate Starvation Response and Actinorhodin Biosynthesis in Streptomyces coelicolor
SM Guerra, A Rodriguez-Garcia, J Santos-Aberturas, CM Vicente, ...
PLoS One 7 (2), e31475, 2012
432012
Warhead biosynthesis and the origin of structural diversity in hydroxamate metalloproteinase inhibitors
F Leipoldt, J Santos-Aberturas, DP Stegmann, F Wolf, A Kulik, R Lacret, ...
Nature Communications 8 (1), 1965, 2017
382017
Hierarchical control on polyene macrolide biosynthesis: PimR modulates pimaricin production via the PAS-LuxR transcriptional activator PimM
J Santos-Aberturas, CM Vicente, TD Payero, L Martin-Sanchez, ...
PLoS One 7 (6), e38536, 2012
372012
Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives
TD Payero, CM Vicente, Á Rumbero, EG Barreales, J Santos-Aberturas, ...
Microbial Cell Factories 14, 1-14, 2015
362015
Activation of secondary metabolite gene clusters in Streptomyces clavuligerus by the PimM regulator of Streptomyces natalensis
Y Martínez-Burgo, J Santos-Aberturas, A Rodríguez-García, EG Barreales, ...
Frontiers in microbiology 10, 439633, 2019
312019
Macroamidine formation in bottromycins is catalyzed by a divergent YcaO enzyme
L Franz, S Adam, J Santos-Aberturas, AW Truman, J Koehnke
Journal of the American Chemical Society 139 (50), 18158-18161, 2017
312017
The system can't perform the operation now. Try again later.
Articles 1–20