Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation L Plate, CB Cooley, JJ Chen, RJ Paxman, CM Gallagher, F Madoux, ... elife 5, e15550, 2016 | 209 | 2016 |
Oligocarbonate molecular transporters: oligomerization-based syntheses and cell-penetrating studies CB Cooley, BM Trantow, F Nederberg, MK Kiesewetter, JL Hedrick, ... Journal of the American Chemical Society 131 (45), 16401-16403, 2009 | 151 | 2009 |
Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells EI Geihe, CB Cooley, JR Simon, MK Kiesewetter, JA Edward, ... Proceedings of the National Academy of Sciences 109 (33), 13171-13176, 2012 | 129 | 2012 |
Restoration of Frequency-Dependent Depression of the H-Reflex by Passive Exercise in Spinal Rats NB Reese, RD Skinner, D Mitchell, C Yates, CN Barnes, TS Kiser, ... Spinal Cord 44, 28-34, 2006 | 107 | 2006 |
Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming JMD Grandjean, A Madhavan, L Cech, BO Seguinot, RJ Paxman, E Smith, ... Nature chemical biology 16 (10), 1052-1061, 2020 | 103 | 2020 |
Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain CB Cooley, LM Ryno, L Plate, GJ Morgan, JD Hulleman, JW Kelly, ... Proceedings of the National Academy of Sciences 111 (36), 13046-13051, 2014 | 93 | 2014 |
Beyond cell penetrating peptides: designed molecular transporters PA Wender, CB Cooley, EI Geihe Drug Discovery Today: Technologies 9 (1), e49-e55, 2012 | 58 | 2012 |
Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells MD Shoulders, LM Ryno, CB Cooley, JW Kelly, RL Wiseman Journal of the American Chemical Society 135 (22), 8129-8132, 2013 | 52 | 2013 |
Developmental Changes in Pedunculopontine Nucleus (PPN) Neurons T Kobayashi, C Good, J Biedermann, C Barnes, RD Skinner, E Garcia-Rill J. Neurophysiology 91, 1470-1481, 2004 | 25 | 2004 |
Fluorogenic atom transfer radical polymerization in aqueous media as a strategy for detection ZT Allen, JR Sackey-Addo, MP Hopps, D Tahseen, JT Anderson, TA Graf, ... Chemical Science 10 (4), 1017-1022, 2019 | 17 | 2019 |
Oligocarbonate molecular transporters C Cooley, JL Hedrick, M Kiesewetter, F Nederberg, B Trantow, ... US Patent 7,939,621, 2011 | 12 | 2011 |
Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. eLife 5 L Plate, CB Cooley, JJ Chen, RJ Paxman, CM Gallagher, F Madoux, ... | 9 | 2016 |
Reactive oxygen species (ROS)-Activatable prodrug for selective activation of ATF6 after ischemia/reperfusion injury JE Palmer, BM Brietske, TC Bate, EA Blackwood, M Garg, CC Glembotski, ... ACS Medicinal Chemistry Letters 11 (3), 292-297, 2019 | 7 | 2019 |
Infrared Reflection–Absorption Spectroscopy of α-Keto Acids at the Air–Water Interface: Effects of Chain Length and Headgroup on Environmentally Relevant Surfactant Films AM Deal, AE Smith, KM Oyala, GH Campolo, BE Rugeley, TA Mose, ... The Journal of Physical Chemistry A 127 (18), 4137-4151, 2023 | 4 | 2023 |
Amphipathic co-oligomers for the delivery of siRNA CB Cooley, EG Stanzl, RM Waymouth, P Wender US Patent 9,902,957, 2018 | 2 | 2018 |
Infrared Reflection-Absorption Spectroscopy of?-Keto Acids at the Air-Water Interface: Effects of Chain Length and Headgroup on Environmentally Relevant Surfactant Films AE Smith, KM Oyala, GH Campolo, BE Rugeley, TA Mose, DL Talley, ... JOURNAL OF PHYSICAL CHEMISTRY A 127 (18), 4137-4151, 2023 | | 2023 |
IRE1 activating compounds for use in therapy RL Wiseman, JW Kelly, JMD Grandjean, CB Cooley, L Plate, E Saez, ... US Patent 11,426,402, 2022 | | 2022 |
Fluorogenic monomer activation for protein-initiated atom transfer radical polymerization D Tahseen, JR Sackey-Addo, ZT Allen, JT Anderson, JB McMurry, ... Organic & Biomolecular Chemistry 20 (31), 6257-6262, 2022 | | 2022 |
Regulators of the Endoplasmic Reticulum Proteostasis Network C Cooley, JW Kelly, R Paxman, L Plate, RL Wiseman US Patent App. 17/445,483, 2021 | | 2021 |
Fluorogenic Atom Transfer Radical Polymerization as a Strategy for Biomolecular Detection D Tahseen, CB Cooley The FASEB Journal 33 (S1), 635.20-635.20, 2019 | | 2019 |