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Hannah Stoveken Lum
Hannah Stoveken Lum
Senior Scientist, Bristol-Myers Squibb
Verified email at bms.com
Title
Cited by
Cited by
Year
Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist
HM Stoveken, AG Hajduczok, L Xu, GG Tall
Proceedings of the National Academy of Sciences 112 (19), 6194-6199, 2015
2322015
Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells
S Giera, R Luo, Y Ying, SD Ackerman, SJ Jeong, HM Stoveken, CJ Folts, ...
Elife 7, e33385, 2018
1102018
Structural basis for regulation of GPR56/ADGRG1 by its alternatively spliced extracellular domains
GS Salzman, SD Ackerman, C Ding, A Koide, K Leon, R Luo, ...
Neuron 91 (6), 1292-1304, 2016
1102016
GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force
J Yeung, R Adili, EN Stringham, R Luo, A Vizurraga, LK Rosselli-Murai, ...
Proceedings of the National Academy of Sciences 117 (45), 28275-28286, 2020
682020
Gedunin-and Khivorin-derivatives are small-molecule partial agonists for adhesion G protein-coupled receptors GPR56/ADGRG1 and GPR114/ADGRG5
HM Stoveken, SD Larsen, AV Smrcka, GG Tall
Molecular pharmacology 93 (5), 477-488, 2018
612018
Dihydromunduletone is a small-molecule selective adhesion G protein–coupled receptor antagonist
HM Stoveken, LL Bahr, MW Anders, AP Wojtovich, AV Smrcka, GG Tall
Molecular pharmacology 90 (3), 214-224, 2016
612016
G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3
S Mathiasen, T Palmisano, NA Perry, HM Stoveken, A Vizurraga, ...
Nature chemical biology 16 (12), 1343-1350, 2020
502020
Genetic behavioral screen identifies an orphan anti-opioid system
D Wang, HM Stoveken, S Zucca, M Dao, C Orlandi, C Song, I Masuho, ...
Science 365 (6459), 1267-1273, 2019
482019
A comprehensive mutagenesis screen of the adhesion GPCR latrophilin-1/ADGRL1
O Nazarko, A Kibrom, J Winkler, K Leon, H Stoveken, G Salzman, ...
IScience 3, 264-278, 2018
402018
Genetic variant in human PAR (Protease-Activated Receptor) 4 enhances thrombus formation resulting in resistance to antiplatelet therapeutics
BE Tourdot, H Stoveken, D Trumbo, J Yeung, Y Kanthi, LC Edelstein, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (7), 1632-1643, 2018
392018
The orphan receptor GPR139 signals via Gq/11 to oppose opioid effects
HM Stoveken, S Zucca, I Masuho, B Grill, KA Martemyanov
Journal of Biological Chemistry 295 (31), 10822-10830, 2020
192020
Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange
MM Papasergi-Scott, HM Stoveken, L MacConnachie, PY Chan, M Gabay, ...
Science Signaling 11 (532), eaap8113, 2018
172018
The role of orphan receptor GPR139 in neuropsychiatric behavior
M Dao, HM Stoveken, Y Cao, KA Martemyanov
Neuropsychopharmacology 47 (4), 902-913, 2022
152022
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking
N Maza, D Wang, C Kowalski, HM Stoveken, M Dao, OK Sial, AC Giles, ...
Nature neuroscience 25 (9), 1179-1190, 2022
122022
Identification of Potential Modulators of the RGS7/Gβ5/R7BP Complex
HM Stoveken, V Fernandez-Vega, BS Muntean, DN Patil, J Shumate, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (9), 1177-1188, 2021
22021
Publisher Correction: G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3
S Mathiasen, T Palmisano, NA Perry, HM Stoveken, A Vizurraga, ...
Nature Chemical Biology 16 (12), 1440-1440, 2020
2020
Activation of Adhesion G Protein-coupled Receptors by a Tethered Agonist: Mechanism of Action and Pharmacological Modulation
HM Stoveken
University of Rochester, 2016
2016
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