Nanobody conjugated PLGA nanoparticles for active targeting of African Trypanosomiasis JL Arias, JD Unciti-Broceta, J Maceira, T Del Castillo, J Hernández-Quero, ... Journal of Controlled Release 197, 190-198, 2015 | 95 | 2015 |
Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis JD Unciti-Broceta, JL Arias, J Maceira, M Soriano, M Ortiz-González, ... PLOS Pathogens 11 (6), 2015 | 77 | 2015 |
Number of Nanoparticles per Cell through a Spectrophotometric Method - A key parameter to Assess Nanoparticle-based Cellular Assays JD Unciti-Broceta, V Cano-Cortés, P Altea-Manzano, S Pernagallo, ... Scientific Reports 5 (10091), 2015 | 53 | 2015 |
Novel therapy based on camelid nanobodies JD Unciti-Broceta, T Del Castillo, M Soriano, S Magez, JA Garcia-Salcedo Therapeutic delivery 4 (10), 1321-1336, 2013 | 51 | 2013 |
A tissue-specific, activation-inducible, lentiviral vector regulated by human CD40L proximal promoter sequences Z Romero, S Torres, M Cobo, P Muñoz, JD Unciti, F Martín, IJ Molina Gene therapy 18 (4), 364-371, 2011 | 38 | 2011 |
New approaches to overcome transport related drug resistance in trypanosomatid parasites JA Garcia-Salcedo, JD Unciti-Broceta, J Valverde-Pozo, M Soriano Frontiers in pharmacology 7, 351, 2016 | 35 | 2016 |
Nicotinamide inhibits the lysosomal cathepsin b-like protease and kills African trypanosomes JD Unciti-Broceta, J Maceira, S Morales, A García-Pérez, ... Journal of Biological Chemistry 288 (15), 10548-10557, 2013 | 30 | 2013 |
Betulinic acid hydroxamate prevents colonic inflammation and fibrosis in murine models of inflammatory bowel disease ME Prados, A García-Martín, JD Unciti-Broceta, B Palomares, JA Collado, ... Acta Pharmacologica Sinica 42 (7), 1124-1138, 2021 | 24 | 2021 |
Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity L Casares, JD Unciti-Broceta, ME Prados, D Caprioglio, D Mattoteia, ... Redox Biology 37, 101689, 2020 | 24 | 2020 |
Identification and characterization of a bacterial hyaluronidase and its production in recombinant form L Messina, JA Gavira, S Pernagallo, JD Unciti‐Broceta, ... FEBS letters 590 (14), 2180-2189, 2016 | 20 | 2016 |
Synthesis of 6,8-9 Poly-substituted Purine Analogue Libraries as Pro-Apoptotic Inducers of Human Leukemic Lymphocytes and DAPK-1 Inhibitors MJ Pineda de las Infantas, S Torres-Rusillo, JD Unciti-Broceta, ... Organic & Biomolecular Chemistry, 2015 | 17 | 2015 |
(+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB1R antagonist/CB2R agonist that prevents diabetic nephropathy in mice I González-Mariscal, B Carmona-Hidalgo, M Winkler, JD Unciti-Broceta, ... Pharmacological Research 169, 105492, 2021 | 14 | 2021 |
Preclinical investigation in neuroprotective effects of the GPR55 ligand VCE-006.1 in experimental models of Parkinson’s disease and amyotrophic lateral sclerosis S Burgaz, C García, C Gonzalo-Consuegra, M Gómez-Almería, ... Molecules 26 (24), 7643, 2021 | 13 | 2021 |
Drug “Clicking” on Cell-Penetrating Fluorescent Nanoparticles for In Cellulo Chemical Proteomics T Valero, A Delgado-González, JD Unciti-Broceta, V Cano-Cortés, ... Bioconjugate chemistry 29 (9), 3154-3160, 2018 | 13 | 2018 |
Amide-controlled, one-pot synthesis of tri-substituted purines generates structural diversity and analogues with trypanocidal activity MJP de las Infantas y Villatoro, JD Unciti-Broceta, R Contreras-Montoya, ... Scientific Reports 5 (9139), 2015 | 13 | 2015 |
Tracking cell proliferation using a nanotechnology-based approach P Altea-Manzano, JD Unciti-Broceta, V Cano-Cortes, MP Ruiz-Blas, ... Nanomedicine 12 (13), 1591-1605, 2017 | 12 | 2017 |
Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2 E Prados, M. E., Correa-Sáez, A., Unciti-Broceta, J. D., Garrido-Rodríguez ... Neurotherapeutics: the journal of the American Society for Experimental …, 2021 | 11* | 2021 |
Safer vectors for gene therapy of primary immunodeficiencies Z Romero, MG Toscano, JD Unciti, IJ Molina, F Martin Current gene therapy 9 (4), 291-305, 2009 | 8 | 2009 |
Neuroprotective Efficacy of Betulinic Acid Hydroxamate, a B55α/PP2A Activator, in Acute Hypoxia–Ischemia-Induced Brain Damage in Newborn Rats L Silva, C Vargas, ME Prados, A Del Pozo, M Villa, M Martínez, L Alvarez, ... Translational Stroke Research 14 (3), 397-408, 2023 | 7 | 2023 |
An effective polymeric nanocarrier that allows for active targeting and selective drug delivery in cell coculture systems MV Cano-Cortes, P Altea-Manzano, JA Laz-Ruiz, JD Unciti-Broceta, ... Nanoscale 13 (6), 3500-3511, 2021 | 6 | 2021 |